Erschienen in:
01.06.2012 | Original Article
A Comparative Evaluation of Early Stent Occlusion Among Biliary Conventional Versus Wing Stents
verfasst von:
Mouen A. Khashab, Susan Hutfless, Katherine Kim, Anne Marie Lennon, Marcia I. Canto, Sanjay B. Jagannath, Patrick I. Okolo III, Eun Ji Shin, Vikesh K. Singh
Erschienen in:
Digestive Diseases and Sciences
|
Ausgabe 6/2012
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Abstract
Background and Study Aims
Conventional plastic stents with a lumen typically have limited patency. The lumenless wing stent was engineered to overcome this problem. The objective of this study was to compare the incidence of early stent occlusion (symptomatic occlusion/cholangitis necessitating re-insertion within 90 days) for wing stents and conventional plastic stents.
Patients and Methods
Patients with biliary pathology treated with plastic biliary stenting during the period 2003–2009 comprised the study cohort. Patients who had at least one biliary wing stent placed comprised the wing stent group, whereas patients who underwent only conventional stent plastic placement comprised the conventional stent group. Patients were stratified by indication: benign biliary strictures (group 1), malignant biliary strictures (group 2), or benign biliary non-stricture pathology (group 3). The association of stent type with the occurrence of primary outcome by indication was analyzed by use of multivariable logistic regression.
Results
Three-hundred and forty-six patients underwent 612 ERCP procedures with placement of plastic biliary stent(s). On multivariate analysis, early stent occlusion did not differ between the wing and conventional groups in groups 1, 2, and 3. Among patients who achieved primary outcome in group 2, significantly fewer patients in the wing group had cholangitis (6.7% vs. 39.1%, P = 0.03). Among patients who achieved primary outcome in group 3, significantly fewer patients in the wing group had cholangitis (10% vs. 50%, P = 0.03).
Conclusions
Early stent occlusion was similar for wing stents and conventional plastic stents. Wing stents, however, were associated with a lower incidence of cholangitis in patients with malignant biliary obstruction and benign non-stricturing biliary pathology.