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Erschienen in: Irish Journal of Medical Science (1971 -) 1/2011

01.03.2011 | Original Article

A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers

verfasst von: M. Shuhaibar, C. Walsh, F. Lindsay, N. Lee, P. Walsh, P. O’Gorman, G. Boran, R. McLoughlin, A. Qasim, N. Breslin, B. Ryan, H. O’Connor, C. O’Morain

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 1/2011

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Abstract

Background

The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening.

Methods

A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy.

Results

A total of 909 faecal testing kits were distributed. Age range was 53–60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polyps and CRC in 37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016).

Conclusion

The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.
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Metadaten
Titel
A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers
verfasst von
M. Shuhaibar
C. Walsh
F. Lindsay
N. Lee
P. Walsh
P. O’Gorman
G. Boran
R. McLoughlin
A. Qasim
N. Breslin
B. Ryan
H. O’Connor
C. O’Morain
Publikationsdatum
01.03.2011
Verlag
Springer-Verlag
Erschienen in
Irish Journal of Medical Science (1971 -) / Ausgabe 1/2011
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-010-0605-0

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