Erschienen in:
01.03.2011 | Original Article
A comparative study of faecal occult blood kits in a colorectal cancer screening program in a cohort of healthy construction workers
verfasst von:
M. Shuhaibar, C. Walsh, F. Lindsay, N. Lee, P. Walsh, P. O’Gorman, G. Boran, R. McLoughlin, A. Qasim, N. Breslin, B. Ryan, H. O’Connor, C. O’Morain
Erschienen in:
Irish Journal of Medical Science (1971 -)
|
Ausgabe 1/2011
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Abstract
Background
The incidence of colorectal cancer (CRC) has been increasing. We evaluated uptake rates and outcomes of faecal immunochemical test (FIT) and Guaiac test (gFOBT) kits as part of a two-step CRC screening.
Methods
A 3-year CRC screening program for a defined population of construction workers was conducted. Those satisfying the inclusion criteria were provided with gFOBT or FIT kits. Individuals testing positive were invited for a colonoscopy.
Results
A total of 909 faecal testing kits were distributed. Age range was 53–60 years. Compliance rate was higher for FIT (58.3%) as compared to gFOBT (46.7%) (p = 0.0006). FIT detected adenomatous polyps and CRC in 37.5 and 25%, respectively, whereas; gFOBT detected 23.5 and 18%. Colonoscopies were normal in 53 and 25% tested positive by gFOBT and FIT, respectively (p = 0.016).
Conclusion
The FIT was more cost-effective when compared with gFOBT with higher return rate, sensitivity and specificity. A comparative study of faecal occult blood kits in a CRC screening program in a healthy cohort of construction workers.