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25.05.2020 | Clinical trial

A comparison of two non-radioactive alternatives to wire for the localization of non-palpable breast cancers

verfasst von: Minna K. Lee, Yas Sanaiha, Amy M. Kusske, Carlie K. Thompson, Deanna J. Attai, Jennifer L. Baker, Cheryce P. Fischer, Maggie L. DiNome

Erschienen in: Breast Cancer Research and Treatment | Ausgabe 2/2020

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Abstract

Purpose

Multiple wire-free technologies for localization of non-palpable breast cancers have emerged as satisfactory alternatives to wire. However, no study has compared two non-radioactive wire-free approaches to one another. The purpose of this study was to compare outcomes among LOCalizer™ radiofrequency identification (RFID), SAVI Scout® (SAVI), and wire localization (WL).

Methods

This was a retrospective, cross-sectional cohort study of patients undergoing lumpectomy for non-palpable breast cancer at a single institution between August 2017 and February 2019. Patients were divided into three cohorts based on localization technique: RFID, SAVI or WL. Operative times and average tumor volumes were compared using one-way analysis of variance. Positive margin and re-excision rates were compared with Fisher’s exact test.

Results

Among 104 patients who underwent lumpectomy for non-palpable breast cancer, 33 patients (31.7%) had RFID, 21 (20.2%) had SAVI, and 50 (48.0%) had WL. Operative times were 79 min for RFID, 81 min for SAVI, and 78 min for WL (p = 0.91). Volume of tissue resected was 36.3 cm³, 31.7 cm³, and 35.3 cm³ for RFID, SAVI, and WL, respectively (p = 0.84). Positive margin rates (RFID 3.0% vs SAVI 9.5% vs WL 8.0%, p = 0.67) and re-excision rates (RFID 6.1% vs SAVI 9.5% vs WL 10.0%, p = 0.82) were similar across groups.

Conclusions

Wire-free localization technologies have been compared to WL demonstrating similar efficacy. Our study suggests that RFID and SAVI Scout also perform similarly to one another. Physicians and institutions may consider more nuanced features of each localization system rather than performance alone when choosing a wire-free alternative.

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Titel: A comparison of two non-radioactive alternatives to wire for the localization of non-palpable breast cancers
verfasst von: Minna K. Lee
Yas Sanaiha
Amy M. Kusske
Carlie K. Thompson
Deanna J. Attai
Jennifer L. Baker
Cheryce P. Fischer
Maggie L. DiNome
Publikationsdatum: 25.05.2020
Verlag: Springer US
Erschienen in: Breast Cancer Research and Treatment / Ausgabe 2/2020
Print ISSN: 0167-6806
Elektronische ISSN: 1573-7217
DOI: https://doi.org/10.1007/s10549-020-05707-1

Springer Medizin

A comparison of two non-radioactive alternatives to wire for the localization of non-palpable breast cancers