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Breast Cancer Research and Treatment

Breast Cancer Research and Treatment OnlineFirst articles

15.11.2017 | Brief Report

Validation of the 8th AJCC prognostic staging system for breast cancer in a population-based setting

More than 1.5 million patients were estimated to be affected with breast cancer in 2012 (according to globocan) [ 1 ]. This made breast cancer the second most common cancer in the world as well as the most common cancer among women. Moreover …

14.11.2017 | Clinical trial Open Access

Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial

Adjuvant chemotherapy improves survival and decreases the risk of recurrence of breast cancer [ 1 ]. However, the treatment is associated with considerable side effects that negatively impact an individual’s health-related quality of life (HRQoL) [ …2

11.11.2017 | Preclinical study Open Access

Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer

The majority of breast tumors are dependent on estrogen signaling for proliferation and survival. Approximately 25% of endocrine-treated breast cancers develop resistance during the course of treatment [ 1 ]. The phosphatidylinositol …

11.11.2017 | Brief Report Open Access

Discordance between oncotype DX recurrence score and RSPC for predicting residual risk of recurrence in ER-positive breast cancer

Breast cancer is the most commonly diagnosed invasive cancer in women worldwide. Its incidence rate varies from 19 per 100,000 women in Eastern Africa to 90 per 100,000 women in Western Europe [ 1 ]. In the UK, it currently represents 31% of all …

11.11.2017 | Clinical trial

21-Gene Recurrence Score for prognosis and prediction of taxane benefit after adjuvant chemotherapy plus endocrine therapy: results from NSABP B-28/NRG Oncology

Gene expression profiling is useful for assessing risk of distant recurrence in patients with early-stage breast cancer and provides additional information to that obtained from traditional histopathologic factors and biomarkers [ 1 – 6 ]. Several …

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