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Erschienen in: Archives of Virology 2/2016

01.02.2016 | Brief Report

A new genotype of border disease virus with implications for molecular diagnostics

verfasst von: Simone Peletto, Claudio Caruso, Francesco Cerutti, Paola Modesto, Simona Zoppi, Alessandro Dondo, Pier Luigi Acutis, Loretta Masoero

Erschienen in: Archives of Virology | Ausgabe 2/2016

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Abstract

Border disease virus (BDV) is a (+) single-stranded RNA pestivirus affecting mainly sheep and goats worldwide. Genetic typing of BDV has led to the identification of at least seven major genotypes. This study reports the detection of a BDV strain from a goat in northwestern Italy during routine investigations. Sequence analysis revealed mutations in the 5’-UTR of the virus with implications for BDV molecular diagnostics. Moreover, subsequent phylogenetic analysis based on the combined 5’-UTR and Npro/partial C genes, showed divergence from known BDV genotypes, revealing the detection of a novel pestivirus group, for which we propose the name BDV genotype 8.
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Metadaten
Titel
A new genotype of border disease virus with implications for molecular diagnostics
verfasst von
Simone Peletto
Claudio Caruso
Francesco Cerutti
Paola Modesto
Simona Zoppi
Alessandro Dondo
Pier Luigi Acutis
Loretta Masoero
Publikationsdatum
01.02.2016
Verlag
Springer Vienna
Erschienen in
Archives of Virology / Ausgabe 2/2016
Print ISSN: 0304-8608
Elektronische ISSN: 1432-8798
DOI
https://doi.org/10.1007/s00705-015-2696-4

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