Skip to main content
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging 11/2010

01.11.2010 | Editorial Commentary

A new PET probe, 18F-tetrafluoroborate, for the sodium/iodide symporter: possible impacts on nuclear medicine

verfasst von: Hyewon Youn, Jae Min Jeong, June-Key Chung

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 11/2010

Einloggen, um Zugang zu erhalten

Excerpt

As early as 1915, it was found that iodide is required in the thyroid gland for the production of thyroid hormones. Since then, radioiodines have been used as tracers in thyroid function tests and as agents for the treatment of hyperthyroidism and benign thyroid diseases. Furthermore, knowledge of the importance of the role played by iodine transport in thyroid cancer cells provides the rationale for the use of radioiodines to diagnose and treat thyroid cancer (1, 2). In fact, the clinical utilization of radioiodines led to the birth of nuclear medicine. …
Literatur
1.
Zurück zum Zitat Fernandes JK, Day TA, Richardson MS, Sharma AK. Overview of the management of differentiated thyroid cancer. Curr Treat Options Oncol 2005;6:47–57.CrossRefPubMed Fernandes JK, Day TA, Richardson MS, Sharma AK. Overview of the management of differentiated thyroid cancer. Curr Treat Options Oncol 2005;6:47–57.CrossRefPubMed
2.
Zurück zum Zitat Chung J-K, Youn HW, Kang JH, Lee HY, Kang KW. Sodium iodide symporter and the radioiodine treatment of thyroid carcinoma. Nucl Med Mol Imaging 2010;44:4–14.CrossRef Chung J-K, Youn HW, Kang JH, Lee HY, Kang KW. Sodium iodide symporter and the radioiodine treatment of thyroid carcinoma. Nucl Med Mol Imaging 2010;44:4–14.CrossRef
3.
Zurück zum Zitat Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature 1996;379:458–60.CrossRefPubMed Dai G, Levy O, Carrasco N. Cloning and characterization of the thyroid iodide transporter. Nature 1996;379:458–60.CrossRefPubMed
4.
Zurück zum Zitat Caillou B, Troalen F, Baudin E, Talbot M, Filetti S, Schlumberg M, et al. Na+/I- symporter distribution in human thyroid tissues: an immunohistochemical study. J Clin Endocrinol Metab 1998;83:4102–6.CrossRefPubMed Caillou B, Troalen F, Baudin E, Talbot M, Filetti S, Schlumberg M, et al. Na+/I- symporter distribution in human thyroid tissues: an immunohistochemical study. J Clin Endocrinol Metab 1998;83:4102–6.CrossRefPubMed
5.
Zurück zum Zitat Chung J-K. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med 2002;43:1188–200.PubMed Chung J-K. Sodium iodide symporter: its role in nuclear medicine. J Nucl Med 2002;43:1188–200.PubMed
6.
Zurück zum Zitat Van Sande J, Massart C, Beauwens R, Schoutens A, Costagliola S, Dumont JE, et al. Anion selectivity by the sodium iodide symporter. Endocrinology 2003;144:247–52.CrossRefPubMed Van Sande J, Massart C, Beauwens R, Schoutens A, Costagliola S, Dumont JE, et al. Anion selectivity by the sodium iodide symporter. Endocrinology 2003;144:247–52.CrossRefPubMed
7.
Zurück zum Zitat Anbar M, Guttmann S, Lewitus Z. Effect of monofluorosulphonate, difluorophosphate and fluoroborate ions on the iodine uptake of the thyroid gland. Nature 1959;183:1517–8.CrossRefPubMed Anbar M, Guttmann S, Lewitus Z. Effect of monofluorosulphonate, difluorophosphate and fluoroborate ions on the iodine uptake of the thyroid gland. Nature 1959;183:1517–8.CrossRefPubMed
8.
Zurück zum Zitat Anbar M, Guttmann S, Lewitus Z. The accumulation of fluoroborate ions in thyroid glands of rats. Endocrinology 1960;66:888–90.CrossRefPubMed Anbar M, Guttmann S, Lewitus Z. The accumulation of fluoroborate ions in thyroid glands of rats. Endocrinology 1960;66:888–90.CrossRefPubMed
9.
Zurück zum Zitat Lambrecht RM, Sajjad M, Qureshi MA, Al-Yanbawi SJ. Production of 124I. J Radioanal Nucl Chem Lett 1988;127:143–50.CrossRef Lambrecht RM, Sajjad M, Qureshi MA, Al-Yanbawi SJ. Production of 124I. J Radioanal Nucl Chem Lett 1988;127:143–50.CrossRef
10.
Zurück zum Zitat Jauregui-Osoro M, Sunassee K, Weeks AJ, Berry DJ, Paul RL, Cleij M, et al. Synthesis and biological evaluation of [18F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter. Eur J Nucl Med Mol Imaging 2010;doi:10.1007/s00259-010-1523-0 Jauregui-Osoro M, Sunassee K, Weeks AJ, Berry DJ, Paul RL, Cleij M, et al. Synthesis and biological evaluation of [18F]tetrafluoroborate: a PET imaging agent for thyroid disease and reporter gene imaging of the sodium/iodide symporter. Eur J Nucl Med Mol Imaging 2010;doi:10.​1007/​s00259-010-1523-0
11.
Zurück zum Zitat Eschmann SM, Reischl G, Bilger K, Kupferschläger J, Thelen MH, Dohmen BM, et al. Evaluation of dosimetry of radioiodine therapy in benign and malignant thyroid disorders by means of iodine-124 and PET. Eur J Nucl Med Mol Imaging 2002;29:760–7.CrossRefPubMed Eschmann SM, Reischl G, Bilger K, Kupferschläger J, Thelen MH, Dohmen BM, et al. Evaluation of dosimetry of radioiodine therapy in benign and malignant thyroid disorders by means of iodine-124 and PET. Eur J Nucl Med Mol Imaging 2002;29:760–7.CrossRefPubMed
12.
Zurück zum Zitat Sgouros G, Kolbert KS, Sheikh A, Pentlow KS, Mun EF, Barth A, et al. Patient-specific dosimetry for 131I thyroid cancer therapy using 124I PET and 3-dimensional-internal dosimetry (3D-ID) software. J Nucl Med 2004;45:1366–72.PubMed Sgouros G, Kolbert KS, Sheikh A, Pentlow KS, Mun EF, Barth A, et al. Patient-specific dosimetry for 131I thyroid cancer therapy using 124I PET and 3-dimensional-internal dosimetry (3D-ID) software. J Nucl Med 2004;45:1366–72.PubMed
13.
Zurück zum Zitat Freudenberg LS, Jentzen W, Görges R, Petrich T, Marlowe RJ, Knust J, et al. 124I-PET dosimetry in advanced differentiated thyroid cancer: therapeutic impact. Nuklearmedizin 2007;46:121–8.PubMed Freudenberg LS, Jentzen W, Görges R, Petrich T, Marlowe RJ, Knust J, et al. 124I-PET dosimetry in advanced differentiated thyroid cancer: therapeutic impact. Nuklearmedizin 2007;46:121–8.PubMed
14.
Zurück zum Zitat Filetti S, Bidart J-M, Arturi F, Caillou B, Russo D, Schlumberger M. Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism. Eur J Endocrinol 1999;141:443–57.CrossRefPubMed Filetti S, Bidart J-M, Arturi F, Caillou B, Russo D, Schlumberger M. Sodium/iodide symporter: a key transport system in thyroid cancer cell metabolism. Eur J Endocrinol 1999;141:443–57.CrossRefPubMed
15.
Zurück zum Zitat Min J-J, Chung J-K, Lee YJ, Jeong JM, Lee DS, Jang JJ, et al. Relationship between expression of the sodium/iodide symporter and 131I uptake in recurrent lesions of differentiated thyroid carcinoma. Eur J Nucl Med 2001;28:639–45.CrossRefPubMed Min J-J, Chung J-K, Lee YJ, Jeong JM, Lee DS, Jang JJ, et al. Relationship between expression of the sodium/iodide symporter and 131I uptake in recurrent lesions of differentiated thyroid carcinoma. Eur J Nucl Med 2001;28:639–45.CrossRefPubMed
16.
Zurück zum Zitat Chung J-K, Kang JH. Translational research using the sodium/iodide symporter in imaging and therapy. Eur J Nucl Med Mol Imaging 2004;31:799–802.CrossRefPubMed Chung J-K, Kang JH. Translational research using the sodium/iodide symporter in imaging and therapy. Eur J Nucl Med Mol Imaging 2004;31:799–802.CrossRefPubMed
Metadaten
Titel
A new PET probe, 18F-tetrafluoroborate, for the sodium/iodide symporter: possible impacts on nuclear medicine
verfasst von
Hyewon Youn
Jae Min Jeong
June-Key Chung
Publikationsdatum
01.11.2010
Verlag
Springer-Verlag
Erschienen in
European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 11/2010
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-010-1601-3

Weitere Artikel der Ausgabe 11/2010

European Journal of Nuclear Medicine and Molecular Imaging 11/2010 Zur Ausgabe