Background
Methods
Study population
Multi Slice CT protocol and MSCT data analysis
Quantification of abdominal aortic calcification
Statistical analysis
Results
All (n = 90) | No CAD (n = 44) | CAD (n = 46) | |
---|---|---|---|
Age, yrs | 67 ± 7 | 65 ± 7 | 69 ± 7* |
Male gender, nr.(%) | 64 (71%) | 27 (61%) | 37 (80%) |
Hemodialysis, nr.(%) | 62 (69%) | 29 (66%) | 33 (72%) |
Dialysis Vintage, months | 18 [9, 29] | 17 [9, 33] | 18 [8, 25] |
BMI | 26.8 ± 4.4 | 26.8 ± 4.5 | 26.8 ± 4.3 |
Hypertension, nr (%) | 70 (77%) | 32 (73%) | 38 (83%) |
Diabetes, nr (%) | 26 (29%) | 12 (27%) | 14 (30%) |
History of smoking, nr (%) | 60 (67%) | 28 (64%) | 32 (70%) |
Beta-Blocker, nr (%) | 45 (50%) | 23 (52%) | 22 (48%) |
ACEi/ARB, nr (%) | 48 (53%) | 21 (48%) | 27 (59%) |
Statin, nr (%) | 45 (50%) | 21 (48%) | 24 (52%) |
Troponin I (ng/L) | 12 [7–22] | 12 [6–24] | 13 [7–17] |
Troponin T (ng/L) | 48 [32–75] | 42 [29–71] | 55 [35–81] |
LV Ejection Fraction (%) | 54% ± 6% | 54% ± 7% | 53% ± 6% |
LVMi (g/m2) | 125 ± 40 | 128 ± 45 | 122 ± 34 |
CACS | 690 [133, 2085] | 279 [20, 1691] | 912 [441, 2217]* |
AAC-score | 8.2 ± 5.1 | 6.3 ± 4.6 | 10.1 ± 4.9* |
Coronary artery disease
Prediction of the presence of coronary artery disease
Univariate | Multivariate | |
---|---|---|
Age | 1.06 (1.00–1.13), p < 0.05 | 1.02 (0.95–1.09), p = 0.64 |
Male gender | 2.59 (1.00–6.68), p < 0.05 | 2.73 (0.95–7.82), p = 0.062 |
Hemodialysis | 1.31 (0.54–3.20), p = 0.55 | |
Dialysis vintage | 1.0 (0.99–1.00), p = 0.42 | |
AACscore (per point) | 1.19 (1.07–1.30), p < 0.05 | 1.18 (1.06–1.32), p < 0.01 |
Diabetes | 1.17 (0.47–2.90), p = 0.74 | |
History of smoking | 1.31 (0.54–3.14), p = 0.55 | |
Hypertension | 1.78 (0.65–4.89), p = 0.26 | |
BMI | 1.0 (0.91–1.10), p = 0.95 |
Sensitivity and Specificity
CAD | No CAD | ||
---|---|---|---|
AACscore ≥6.5 | 39 | 19 |
PPV : 67% |
AACscore <6.5 | 7 | 25 |
NPV : 78% |
Sensitivity : 85% |
Specificity : 57% |