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Techniques in Coloproctology
Erschienen in: Techniques in Coloproctology 4/2020

15.02.2020 | Review

Abnormal gut motility in inflammatory bowel disease: an update

verfasst von: G. Bassotti, E. Antonelli, V. Villanacci, R. Nascimbeni, M. P. Dore, G. M. Pes, G. Maconi

Erschienen in: Techniques in Coloproctology | Ausgabe 4/2020

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Abstract

Background

There is substantial evidence linking disturbed gastrointestinal motility to inflammation. Thus, it is not surprising that abnormalities of gastrointestinal motility play a role in inflammatory bowel disease (IBD), affecting patient outcomes. We performed a review of the literature to investigate the relationship between abnormal gut motility and IBD.

Methods

With an extensive literature search, we retrieved the pertinent articles linking disturbed gut motility to IBD in various anatomical districts.

Results

The evidence in the literature suggests that abnormal gastrointestinal motility plays a role in the clinical setting of IBD and may confuse the clinical picture.

Conclusions

Abnormal gut motility may be important in the clinical setting of IBD. However, additional data obtained with modern techniques (e.g., magnetic resonance imaging) are needed to individuate in a more precise manner gastrointestinal motor dysfunctions, to understand the nature of clinical manifestations and properly tailor the treatment of patients.
Literatur
1.
Spiller R, Major G (2016) IBS and IBD—separate entities or on a spectrum? Nat Rev Gastroenterol Hepatol 13:613–621PubMed
2.
Bassotti G, Antonelli E, Villanacci V et al (2014) Gastrointestinal motility disorders in inflammatory bowel diseases. World J Gastroenterol 20:37–44PubMedPubMedCentral
3.
Villanacci V, Bassotti G, Nascimbeni R, Salemme M, Coppola M, Annese V (2008) Enteric nervous system abnormalities in inflammatory bowel diseases. Neurogastroenterol Motil 20:1009–1016PubMed
4.
Bassotti G, Villanacci V, Nascimbeni R et al (2009) Enteric neuroglial apoptosis in inflammatory bowel diseases. J Crohns Colitis 3:264–270PubMed
5.
Ohman L, Simrén M (2010) Pathogenesis of IBS: role of inflammation, immunity and neuroimmune interactions. Nat Rev Gastroenterol Hepatol 7:163–173PubMed
6.
Abdalla SM, Kalra G, Moshiree B (2016) Motility evaluation in the patient with inflammatory bowel disease. Gastrointest Endosc Clin N Am 26:719–738PubMed
7.
Halpin SJ, Ford AC (2012) Prevalence of symptoms meeting criteria for irritable bowel syndrome in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol 107:1474–1482PubMed
8.
Lazarev M, Huang C, Bitton A et al (2013) Relationship between proximal Crohn's disease location and disease behavior and surgery: a cross-sectional study of the IBD Genetics Consortium. Am J Gastroenterol 108:106–112PubMed
9.
Usai P, Bassotti G, Usai Satta P et al (1995) Oesophageal motility in adult coeliac disease. Neurogastroenterol Motil 7:239–244PubMed
10.
Knoblauch C, Netzer P, Scheurer U, Seibold F (2002) Dysphagia in Crohn's disease: a diagnostic challenge. Dig Liver Dis 34:660–664PubMed
11.
Kelly OB, O'Donnell S, O'Moráin CA (2010) A case of achalasia diagnosed first on capsule endoscopy: find that hard to swallow? Eur J Gastroenterol Hepatol 22:1013–1314PubMed
12.
Treem WR, Ragsdale BD (1988) Crohn's disease of the esophagus: a case report and review of the literature. J Pediatr Gastroenterol Nutr 7:451–455PubMed
13.
Katz J, Shenkman A, Stavropoulos F, Melzer E (2003) Oral signs and symptoms in relation to disease activity and site of involvement in patients with inflammatory bowel disease. Oral Dis 9:34–40PubMed
14.
Barratt SM, Leeds JS, Robinson K et al (2011) Reflux and irritable bowel syndrome are negative predictors of quality of life in coeliac disease and inflammatory bowel disease. Eur J Gastroenterol Hepatol 23:159–165PubMed
15.
Sonnenberg A, Turner KO, Genta RM (2018) Decreased risk for microscopic colitis and inflammatory bowel disease among patients with reflux disease. Colorect Dis 20:813–820
16.
Danelius M, Ost A, Lapidus AB (2009) Inflammatory bowel disease-related lesions in the duodenal and gastric mucosa. Scand J Gastroenterol 44:441–445PubMed
17.
Gryboski JD, Burger J, McCallum R, Lange R (1992) Gastric emptying in childhood inflammatory bowel disease: nutritional and pathologic correlates. Am J Gastroenterol 87:1148–1153PubMed
18.
Grill BB, Lange R, Markowitz R, Hillemeier AC, McCallum RW, Gryboski JD (1985) Delayed gastric emptying in children with Crohn's disease. J Clin Gastroenterol 7:216–226PubMed
19.
Rao SS, Read NW (1990) Gastrointestinal motility in patients with ulcerative colitis. Scand J Gastroenterol Suppl 172:22–28PubMed
20.
Nóbrega AC, Ferreira BR, Oliveira GJ et al (2012) Dyspeptic symptoms and delayed gastric emptying of solids in patients with inactive Crohn's disease. BMC Gastroenterol 12:175PubMedPubMedCentral
21.
Dew MJ, Harries AD, Rhodes M, Rhodes J, Leach KG (1983) Gastric emptying after intestinal resection in Crohn's disease. Br J Surg 70:92–93PubMed
22.
Annese V, Bassotti G, Napolitano G et al (1995) Gastric emptying of solids in patients with nonobstructive Crohn's disease is sometimes delayed. J Clin Gastroenterol 21:279–282PubMed
23.
Keller J, Binnewies U, Rösch M et al (2015) Gastric emptying and disease activity in inflammatory bowel disease. Eur J Clin Invest 45:1234–1242PubMed
24.
Sharma P, Makharia G, Yadav R, Dwivedi SN, Deepak KK (2015) Gastric myoelectrical activity in patients with inflammatory bowel disease. J Smooth Muscle Res 51:50–57PubMedPubMedCentral
25.
Lin J, Shen B, Lee HJ, Goldblum JR (2012) Histopathological characterization of cholecystectomy specimens in patients with inflammatory bowel disease. J Crohns Colitis 6:895–989PubMed
26.
Masclee AA, Vu MK (2003) Gallbladder motility in inflammatory bowel diseases. Dig Liver Dis 35(Suppl 3):S35–38PubMed
27.
Stolk MF, Van Erpecum KJ, Hiemstra G, Jansen JB, Van Berge-Henegouwen GP (1994) Gallbladder motility and cholecystokinin release during long-term enteral nutrition in patients with Crohn's disease. Scand J Gastroenterol 29:934–939PubMed
28.
Ledeboer M, Masclee AA, Biemond I, Lamers CB (1997) Gallbladder motility and cholecystokinin secretion during continuous enteral nutrition. Am J Gastroenterol 92:2274–2279PubMed
29.
Vu MK, Gielkens HA, van Hogezand RA, van Oostayen JA, Lamers CB, Masclee AA (2000) Gallbladder motility in Crohn disease: influence of disease localization and bowel resection. Scand J Gastroenterol 35:1157–1162PubMed
30.
Annese V, Bassotti G, Napolitano G et al (1993) Most patients with inactive Crohn’s disease have gastrointestinal motility disorders. Gastroenterology 104(suppl):A470
31.
Wouters MM, Boeckxstaens GE (2011) Neuroimmune mechanisms in functional bowel disorders. Neth J Med 69:55–61PubMed
32.
Mourad FH, Barada KA, Saade NE (2017) Impairment of small intestinal function in ulcerative colitis: role of enteric innervation. J Crohns Colitis 11:369–377PubMed
33.
Al-Saffar A, Hellström PM (2001) Contractile responses to natural tachykinins and selective tachykinin analogs in normal and inflamed ileal and colonic muscle. Scand J Gastroenterol 36:485–493PubMed
34.
Peuhkuri K, Vapaatalo H, Korpela R (2010) Even low-grade inflammation impacts on small intestinal function. World J Gastroenterol 16:1057–1062PubMedPubMedCentral
35.
Straub RH, Antoniou E, Zeuner M, Gross V, Schölmerich J, Andus T (1997) Association of autonomic nervous hyperreflexia and systemic inflammation in patients with Crohn's disease and ulcerative colitis. J Neuroimmunol 80:149–157PubMed
36.
Jonefjäll B, Strid H, Ohman L, Svedlund J, Bergstedt A, Simren M (2013) Characterization of IBS-like symptoms in patients with ulcerative colitis in clinical remission. Neurogastroenterol Motil 25:756–e578PubMed
37.
Mavroudis G, Simren M, Jonefjäll B, Öhman L, Strid H (2019) Symptoms compatible with functional bowel disorders are common in patients with quiescent ulcerative colitis and influence the quality of life but not the course of the disease. Therap Adv Gastroenterol 12:1756284819827689PubMedPubMedCentral
38.
Ananthakrishnan AN, Issa M, Barboi A et al (2010) Impact of autonomic dysfunction on inflammatory bowel disease. J Clin Gastroenterol 44:272–279PubMed
39.
Camilleri M, Lasch K, Zhou W (2012) Irritable bowel syndrome: methods, mechanisms, and pathophysiology. The confluence of increased permeability, inflammation, and pain in irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol 303:G775–G785PubMed
40.
Berrill JW, Green JT, Hood K, Campbell AK (2013) Symptoms of irritable bowel syndrome in patients with inflammatory bowel disease: examining the role of sub-clinical inflammation and the impact on clinical assessment of disease activity. Aliment Pharmacol Ther 38:44–51PubMed
41.
Serra J, Villoria A, Azpiroz F et al (2010) Impaired intestinal gas propulsion in manometrically proven dysmotility and in irritable bowel syndrome. Neurogastroenterol Motil 22:401–446PubMed
42.
Lahiff C, Safaie P, Awais A et al (2013) The Crohn's disease activity index (CDAI) is similarly elevated in patients with Crohn's disease and in patients with irritable bowel syndrome. Aliment Pharmacol Ther 37:786–794PubMed
43.
Nemakayala DR, Cash BD (2019) Excluding irritable bowel syndrome in the inflammatory bowel disease patient: how far to go? Curr Opin Gastroenterol 35:58–62PubMed
44.
Malagelada C, Malagelada JR (2017) Small bowel motility. Curr Gastroenterol Rep 19:26PubMed
45.
Haase AM, Gregersen T, Christensen LA et al (2016) Regional gastrointestinal transit times in severe ulcerative colitis. Neurogastroenterol Motil 28:217–224PubMed
46.
Fischer M, Siva S, Wo JM, Fadda HM (2017) Assessment of small intestinal transit times in ulcerative colitis and Crohn's disease patients with different disease activity using video capsule endoscopy. AAPS PharmSciTech 18:404–409PubMed
47.
James SL, van Langenberg DR, Taylor KM, Gibson PR (2018) Characterization of ulcerative colitis-associated constipation syndrome (proximal constipation). JGH Open 2:217–222PubMedPubMedCentral
48.
Manousos ON, Salem SN (1965) Abnormal motility of the small intestine in ulcerative colitis. Gastroenterologia 104:249–257PubMed
49.
Ritchie JA, Salem SN (1965) Upper intestinal motility in ulcerative colitis, idiopathic steatorrhoea, and the irritable colon syndrome. Gut 6:325–337PubMedPubMedCentral
50.
Stryker SJ, Borody TJ, Phillips SF, Kelly KA, Dozois RR, Beart RW (1985) Motility of the small intestine after proctocolectomy and ileal pouch-anal anastomosis. Ann Surg 201:351–356PubMedPubMedCentral
51.
Chaussade S, Merite F, Hautefeuille M, Valleur P, Hautefeuille P, Couturier D (1989) Motility of the jejunum after proctocolectomy and ileal pouch anastomosis. Gut 30:371–375PubMedPubMedCentral
52.
Bassotti G, Castagnoli G, Trancanelli V, Pelli MA, Morelli A (1991) Patients with ileal-pouch anal anastomosis display contractile abnormalities of the reservoir and of upper ileum. Dig Surg 8:10–14
53.
Summers RW, Anuras S, Green J (1983) Jejunal manometry patterns in health, partial intestinal obstruction, and pseudoobstruction. Gastroenterology 85:1290–1300PubMed
54.
Bassotti G, Stanghellini V, Chiarioni G et al (1996) Upper gastrointestinal motor activity in patients with slow-transit constipation. Further evidence for an enteric neuropathy. Dig Dis Sci 41:1999–2005PubMed
55.
De Giorgio R, Stanghellini V, Barbara G et al (2000) Primary enteric neuropathies underlying gastrointestinal motor dysfunction. Scand J Gastroenterol 35:114–122PubMed
56.
Ducrotte P, Koning E, Guillemot F et al (1989) Jejunal motility during cyclic total parenteral nutrition in patients with Crohn's disease. Gut 30:815–819PubMedPubMedCentral
57.
Annese V, Bassotti G, Napolitano G, Usai P, Andriulli A, Vantrappen G (1997) Gastrointestinal motility disorders in patients with inactive Crohn's disease. Scand J Gastroenterol 32:1107–1117PubMed
58.
59.
Gollifer RM, Menys A, Makanyanga J et al (2018) Relationship between MRI quantified small bowel motility and abdominal symptoms in Crohn's disease patients-a validation study. Br J Radiol 91:20170914PubMedPubMedCentral
60.
Menys A, Puylaert C, Tutein Nolthenius CE et al (2018) Quantified terminal ileal motility during MR enterography as a biomarker of Crohn disease activity: prospective multi-institution study. Radiology 289:428–435PubMed
61.
Åkerman A, Månsson S, Fork FT et al (2016) Computational postprocessing quantification of small bowel motility using magnetic resonance images in clinical practice: an initial experience. J Magn Reson Imaging 44:277–287PubMed
62.
Rao SS, Camilleri M, Hasler WL et al (2011) Evaluation of gastrointestinal transit in clinical practice: position paper of the American and European Neurogastroenterology and Motility Societies. Neurogastroenterol Motil 23:8–23PubMed
63.
Yung D, Douglas S, Hobson AR, Giannakou A, Plevris JN, Koulaouzidis A (2016) Morpho-functional evaluation of small bowel using wireless motility capsule and video capsule endoscopy in patients with known or suspected Crohn's disease: pilot study. Endosc Int Open 4:E480–486PubMedPubMedCentral
64.
Laus F, Fratini M, Paggi E et al (2017) Effects of single-dose prucalopride on intestinal hypomotility in horses: preliminary observations. Sci Rep 7:41526PubMedPubMedCentral
65.
Bassotti G, Antonelli E, Villanacci V, Baldoni M, Dore MP (2014) Colonic motility in ulcerative colitis. United Eur Gastroenterol J 2:457–462
66.
Neunlist M, Aubert P, Toquet C et al (2003) Changes in chemical coding of myenteric neurones in ulcerative colitis. Gut 52:84–90PubMedPubMedCentral
67.
Verma-Gandhu M, Verdu EF, Bercik P et al (2007) Visceral pain perception is determined by the duration of colitis and associated neuropeptide expression in the mouse. Gut 56:358–364PubMed
68.
La JH, Kim TW, Sung TS (2003) Visceral hypersensitivity and altered colonic motility after subsidence of inflammation in a rat model of colitis. World J Gastroenterol 9:2791–2795PubMedPubMedCentral
69.
Choi K, Chen J, Mitra S, Sarna SK (2011) Impaired integrity of DNA after recovery from inflammation causes persistent dysfunction of colonic smooth muscle. Gastroenterology 141:1293–1301PubMedPubMedCentral
70.
Villanacci V, Antonelli E, Geboes K, Casella G, Bassotti G (2013) Histological healing in inflammatory bowel disease: a still unfulfilled promise. World J Gastroenterol 19:968–978PubMedPubMedCentral
71.
Mazzuoli S, Guglielmi FW, Antonelli E, Salemme M, Bassotti G, Villanacci V (2013) Definition and evaluation of mucosal healing in clinical practice. Dig Liver Dis 45:969–977PubMed
72.
Vivinus-Nébot M, Frin-Mathy G, Bzioueche H et al (2014) Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation. Gut 63:744–752PubMed
73.
Bassotti G, Villanacci V, Antonelli E, Morelli A, Salerni B (2007) Enteric glial cells: new players in gastrointestinal motility? Lab Invest 87:628–632PubMed
74.
Morales-Soto W, Gulbransen BD (2019) Enteric glia: a new player in abdominal pain. Cell Mol Gastroenterol Hepatol 7:433–445PubMed
75.
Ippolito C, Colucci R, Segnani C et al (2016) Fibrotic and vascular remodelling of colonic wall in patients with active ulcerative colitis. J Crohns Colitis 10:1194–1204PubMed
76.
Kern F, Almy TP, Abbot FK, Bogdonoff MD (1951) The motility of the distal colon in nonspecific ulcerative colitis. Gastroenterology 19:492–503PubMed
77.
Spriggs EA, Code CF, Bargen JA, Curtiss RK, Hightower NC (1951) Motility of the pelvic colon and rectum of normal persons and patients with ulcerative colitis. Gastroenterology 19:480–491PubMed
78.
Connell AM (1962) The motility of the pelvic colon. II. Paradoxical motility in diarrhoea and constipation. Gut 3:342–348PubMedPubMedCentral
79.
Jalan KN, Walker RJ, Prescott RJ, Butterworth ST, Smith AN, Sircus W (1970) Faecal stasis and diverticular disease in ulcerative colitis. Gut 11:688–696PubMedPubMedCentral
80.
Reddy SN, Bazzocchi G, Chan S et al (1991) Colonic motility and transit in health and ulcerative colitis. Gastroenterology 101:1289–1297PubMed
81.
Bassotti G, de Roberto G, Chistolini F, Sietchiping-Nzepa F, Morelli O, Morelli A (2004) Twenty-four-hour manometric study of colonic propulsive activity in patients with diarrhea due to inflammatory (ulcerative colitis) and non-inflammatory (irritable bowel syndrome) conditions. Int J Colorectal Dis 19:493–497PubMed
82.
Bassotti G, Gaburri M, Imbimbo BP, Morelli A, Whitehead WE (1994) Distension-stimulated propagated contractions in human colon. Dig Dis Sci 39:1955–1960PubMed
83.
Bassotti G, Villanacci V, Mazzocchi A et al (2006) Colonic propulsive and postprandial motor activity in patients with ulcerative colitis in remission. Eur J Gastroenterol Hepatol 18:507–510PubMed
84.
Dinakaran V, Mandape SN, Shuba K et al (2019) Identification of specific oral and gut pathogens in full thickness colon of colitis patients: implications for colon motility. Front Microbiol 9:3220PubMedPubMedCentral
85.
Nigam GB, Limdi JK, Vasant DH (2018) Current perspectives on the diagnosis and management of functional anorectal disorders in patients with inflammatory bowel disease. Therap Adv Gastroenterol 11:1756284818816956PubMedPubMedCentral
86.
Perera LP, Ananthakrishnan AN, Guilday C et al (2013) Dyssynergic defecation: a treatable cause of persistent symptoms when inflammatory bowel disease is in remission. Dig Dis Sci 58:3600–3605PubMed
87.
Chrysos E, Athanasakis E, Tsiaoussis J et al (2001) Rectoanal motility in Crohn's disease patients. Dis Colon Rectum 44:1509–1513PubMed
88.
Mueller MH, Kreis ME, Gross ML, Becker HD, Zittel TT, Jehle EC (2002) Anorectal functional disorders in the absence of anorectal inflammation in patients with Crohn's disease. Br J Surg 89:1027–1031PubMed
89.
Kangas E, Hiltunen KM, Matikainen M (1992) Anorectal function in Crohn's disease. Ann Chir Gynaecol 81:43–47PubMed
90.
Papathanasopoulos A, Van Oudenhove L, Katsanos K, Christodoulou D, Tack J, Tsianos EV (2013) Severity of fecal urgency and incontinence in inflammatory bowel disease: clinical, manometric and sonographic predictors. Inflamm Bowel Dis 19:2450–2456PubMed
91.
Keighley MR, Buchmann P, Lee JR (1982) Assessment of anorectal function in selection of patients for ileorectal anastomosis in Crohn's colitis. Gut 23:102–107PubMedPubMedCentral
92.
Rao SS, Read NW, Davison PA, Bannister JJ, Holdsworth CD (1987) Anorectal sensitivity and responses to rectal distention in patients with ulcerative colitis. Gastroenterology 93:1270–1275PubMed
93.
Rao SS, Read NW, Stobart JA, Haynes WG, Benjamin S, Holdsworth CD (1988) Anorectal contractility under basal conditions and during rectal infusion of saline in ulcerative colitis. Gut 29:769–777PubMedPubMedCentral
94.
Brochard C, Siproudhis L, Ropert A, Mallak A, Bretagne JF, Bouguen G (2015) Anorectal dysfunction in patients with ulcerative colitis: impaired adaptation or enhanced perception? Neurogastroenterol Motil 27:1032–1037PubMed
95.
Heppell J, Taylor BM, Beart RW, Dozois RR, Kelly KA (1983) Predicting outcome after endorectal ileoanal anastomosis. Can J Surg 26:132–134PubMed
96.
Holdsworth PJ, Sagar PM, Lewis WG, Williamson M, Johnston D (1994) Internal anal sphincter activity after restorative proctocolectomy for ulcerative colitis: a study using continuous ambulatory manometry. Dis Colon Rectum 37:32–36PubMed
97.
Saigusa N, Belin BM, Choi HJ et al (2003) Recovery of the rectoanal inhibitory reflex after restorative proctocolectomy: does it correlate with nocturnal continence? Dis Colon Rectum 46:168–172PubMed
98.
Rink AD, Kneist W, Radinski I, Guinot-Barona A, Lang H, Vestweber KH (2010) Differences in ano-neorectal physiology of ileoanal and coloanal reconstructions for restorative proctectomy. Colorectal Dis 12:342–350PubMed
99.
Colombel JF, Shin A, Gibson PR (2019) AGA Clinical practice update on functional gastrointestinal symptoms in patients with inflammatory bowel disease: expert review. Clin Gastroenterol Hepatol 17:380–390PubMed
100.
Ishihara S, Kawashima K, Fukuba N et al (2019) Irritable bowel syndrome-like symptoms in ulcerative colitis patients in clinical remission: association with residual colonic inflammation. Digestion 99:46–51PubMed
Metadaten
Titel
Abnormal gut motility in inflammatory bowel disease: an update
verfasst von
G. Bassotti
E. Antonelli
V. Villanacci
R. Nascimbeni
M. P. Dore
G. M. Pes
G. Maconi
Publikationsdatum
15.02.2020
Verlag
Springer International Publishing
Erschienen in
Techniques in Coloproctology / Ausgabe 4/2020
Print ISSN: 1123-6337
Elektronische ISSN: 1128-045X
DOI
https://doi.org/10.1007/s10151-020-02168-y

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