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Erschienen in: International Journal of Hematology 3/2017

02.05.2017 | Original Article

Allogeneic hematopoietic stem cell transplantation for refractory mycosis fungoides (MF) and Sezary syndrome (SS)

verfasst von: Erden Atilla, Pinar Ataca Atilla, Sinem Civriz Bozdag, Meltem Kurt Yuksel, Selami Kocak Toprak, Pervin Topcuoglu, Bengu Nisa Akay, Hatice Sanli, Gunhan Gurman, Muhit Ozcan

Erschienen in: International Journal of Hematology | Ausgabe 3/2017

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Abstract

Cutaneous T cell lymphoma is a heterogeneous group of lymphoproliferative disorders with different clinical behavior and prognosis in which malignant T cells accumulate in the skin. In the relapsed/refractory stage, treatment strategy varies depending on clinical perspective. We retrospectively evaluated advanced stage relapse or refractory mycosis fungoides and Sezary syndrome patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) at our hospital. The overall response rate was 25%, while the disease progressed and relapsed after transplant in 38% of patients. Allo-HSCT may be a reasonable treatment option in the relapsed/refractory stage.
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Metadaten
Titel
Allogeneic hematopoietic stem cell transplantation for refractory mycosis fungoides (MF) and Sezary syndrome (SS)
verfasst von
Erden Atilla
Pinar Ataca Atilla
Sinem Civriz Bozdag
Meltem Kurt Yuksel
Selami Kocak Toprak
Pervin Topcuoglu
Bengu Nisa Akay
Hatice Sanli
Gunhan Gurman
Muhit Ozcan
Publikationsdatum
02.05.2017
Verlag
Springer Japan
Erschienen in
International Journal of Hematology / Ausgabe 3/2017
Print ISSN: 0925-5710
Elektronische ISSN: 1865-3774
DOI
https://doi.org/10.1007/s12185-017-2245-x

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