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01.12.2016 | Report

Altered Resting-State Signals in Patients with Acute Stroke In or Under the Thalamus

verfasst von: Lijun Chen, Chuanfu Li, Jian Zhai, Anqin Wang, Qin Song, Ying Liu, Ru Ma, Long Han, Yamikani Ndasauka, Xiaoming Li, Hai Li, Xiaochu Zhang

Erschienen in: Neuroscience Bulletin | Ausgabe 6/2016

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Abstract

Previous studies have suggested that cortical functional reorganization is associated with motor recovery after stroke and that normal afferent sensory information is very important in that process. In this study, we selected patients who had a stroke in or under the thalamus, with potentially impaired afferent sensory information and analyzed the differences between these patients and healthy controls at three levels: brain regions, the functional connectivity between brain areas, and the whole-brain functional network. Compared with healthy controls, regional homogeneities in the left middle temporal gyrus decreased and functional connectivity between the left middle temporal gyrus and the stroke area increased in the patients. However, there was no significant change in the whole-brain functional network. By focusing on stroke located in or under the thalamus, our study contributes to wider inquiries into understanding and treating stroke.

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Varsou O, Macleod MJ, Schwarzbauer C. Functional connectivity magnetic resonance imaging in stroke: an evidence-based clinical review. Int J Stroke 2014, 9: 191–198.CrossRefPubMed

Li W, Han T, Qin W, Zhang J, Liu H, Li Y, et al. Altered functional connectivity of cognitive-related cerebellar subregions in well-recovered stroke patients. Neural Plast 2013, 2013. doi:10.1155/2013/452439.

Rosamond W, Flegal K, Friday G, Furie K, Go A, Greenlund K, et al. Heart disease and stroke statistics-2007 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2007, 115: e69–e171.CrossRefPubMed

Hosp JA, Luft AR. Cortical plasticity during motor learning and recovery after ischemic stroke. Neural Plast 2011, 2011. doi:10.1155/2011/871296.

Faralli A, Bigoni M, Mauro A, Rossi F, Carulli D. Noninvasive strategies to promote functional recovery after stroke. Neural Plast 2013, 2013. doi:10.1155/2013/854597.

Dijkhuizen RM, van der Marel K, Otte WM, Hoff EI, van der Zijden JP, van der Toorn A, et al. Functional MRI and diffusion tensor imaging of brain reorganization after experimental stroke. Transl Stroke Res 2012, 3: 36–43.CrossRefPubMedPubMedCentral

Tombari D, Loubinoux I, Pariente J, Gerdelat A, Albucher JF, Tardy J, et al. A longitudinal fMRI study: in recovering and then in clinically stable sub-cortical stroke patients. Neuroimage 2004, 23: 827–839.CrossRefPubMed

Shim YS, Kim JS, Shon YM, Chung YA, Ahn KJ, Yang DW. A serial study of regional cerebral blood flow deficits in patients with left anterior thalamic infarction: anatomical and neuropsychological correlates. J Neurol Sci 2008, 266: 84–91.CrossRefPubMed

Basso MA, Uhlrich D, Bickford ME. Cortical function: a view from the thalamus. Neuron 2005, 45: 485–488.CrossRefPubMed

10.

Behrens TEJ, Johansen-Berg H, Woolrich MW, Smith SM, Wheeler-Kingshott CAM, Boulby P A, et al. Non-invasive mapping of connections between human thalamus and cortex using diffusion imaging. Nat Neurosci 2003, 6: 750–757.CrossRefPubMed

11.

Park CH, Chang WH, Ohn SH, Kim ST, Bang OY, Pascual-Leone A, et al. Longitudinal changes of resting-state functional connectivity during motor recovery after stroke. Stroke 2011, 42: 1357–1362.CrossRefPubMedPubMedCentral

12.

Wang Z, Yuan Y, Bai F, Shu H, You J, Li L, et al. Altered functional connectivity networks of hippocampal subregions in remitted late-onset depression: a longitudinal resting-state study. Neurosci Bull 2015, 31: 13–21.CrossRefPubMed

13.

Wang P, Du H, Chen N, Guo J, Gong Q, Zhang J, et al. Regional homogeneity abnormalities in patients with tensiontype headache: a resting-state fMRI study. Neurosci Bull 2014, 30: 949–955.CrossRefPubMed

14.

Lei X, Yang T, Wu T. Functional neuroimaging of extraversion-introversion. Neurosci Bull 2015, 31: 663–675.CrossRefPubMed

15.

Zang Y, Jiang T, Lu Y, He Y, Tian L. Regional homogeneity approach to fMRI data analysis. Neuroimage 2004, 22: 394–400.CrossRefPubMed

16.

Tsai YH, Yuan R, Huang YC, Yeh MY, Lin CP, Biswal BB. Disruption of brain connectivity in acute stroke patients with early impairment in consciousness. Front Psychol 2014, 4: 956.CrossRefPubMedPubMedCentral

17.

Yin D, Luo Y, Song F, Xu D, Peterson BS, Sun L, et al. Functional reorganization associated with outcome in hand function after stroke revealed by regional homogeneity. Neuroradiology 2013, 55: 761–770.CrossRefPubMed

18.

Zhang Y, Liu H, Wang L, Yang J, Yan R, Zhang J, et al. Relationship between functional connectivity and motor function assessment in stroke patients with hemiplegia: a resting-state functional MRI study. Neuroradiology 2016, 58: 503–511.CrossRefPubMed

19.

Liao W, Zhang Z, Pan Z, Mantini D, Ding J, Duan X, et al. Altered functional connectivity and small-world in mesial temporal lobe epilepsy. PLoS One 2010, 5: e8525.CrossRefPubMedPubMedCentral

20.

Liu Y, Liang M, Zhou Y, He Y, Hao Y, Song M, et al. Disrupted small-world networks in schizophrenia. Brain 2008, 131: 945–961.CrossRefPubMed

21.

Yin D, Song F, Xu D, Sun L, Men W, Zang L, et al. Altered topological properties of the cortical motor-related network in patients with subcortical stroke revealed by graph theoretical analysis. Hum Brain Mapp 2014, 35: 3343–3359.CrossRefPubMed

22.

Wang L, Zhu C, He Y, Zang Y, Cao Q, Zhang H, et al. Altered small-world brain functional networks in children with attention-deficit/hyperactivity disorder. Hum Brain Mapp 2009, 30: 638–649.CrossRefPubMed

23.

Xu C, Li C, Wu H, Wu Y, Hu S, Zhu Y, et al. Gender differences in cerebral regional homogeneity of adult healthy volunteers: A resting-state fMRI study. Biomed Res Int 2015, 2015. doi:10.1155/2015/183074.

24.

Tzourio-Mazoyer N, Landeau B, Papathanassiou D, Crivello F, Etard O, Delcroix N, et al. Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain. Neuroimage 2002, 15: 273–289.CrossRefPubMed

25.

He Y, Chen Z, Evans A. Structural insights into aberrant topological patterns of large-scale cortical networks in Alzheimer’s disease. J Neurosci 2008, 28: 4756–4766.CrossRefPubMed

26.

Achard S, Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Comput Biol 2007, 3: e17.CrossRefPubMedPubMedCentral

27.

Stam CJ, Jones BF, Nolte G, Breakspear M, Scheltens P. Small-world networks and functional connectivity in Alzheimer’s disease. Cereb Cortex 2007, 17: 92–99.CrossRefPubMed

28.

Bassett DS, Bullmore ED. Small-world brain networks. Neuroscientist 2006, 12: 512–523.CrossRefPubMed

29.

Achard S, Salvador R, Whitcher B, Suckling J, Bullmore ED. A resilient, low-frequency, small-world human brain functional network with highly connected association cortical hubs. J Neurosci 2006, 26: 63–72.CrossRefPubMed

30.

Bing D, Chen L. Clinical Neuroanatomy. 1th ed. Beijing: People’s Medical Publishing House, 2007: 349–362.

31.

Raettig T, Kotz SA. Auditory processing of different types of pseudo-words: an event-related fMRI study. Neuroimage 2008, 39: 1420–1428.CrossRefPubMed

32.

Zhou B, Liu Y, Zhang Z, An N, Yao H, Wang P, et al. Impaired functional connectivity of the thalamus in Alzheimer’s disease and mild cognitive impairment: a resting-state fMRI study. Curr Alzheimer Res 2013, 10: 754–766.CrossRefPubMed

33.

Johansen-Berg H, Behrens TE, Sillery E, Ciccarelli O, Thompson AJ, Smith SM, et al. Functional-anatomical validation and individual variation of diffusion tractography-based segmentation of the human thalamus. Cereb Cortex 2005; 15: 31–39.CrossRefPubMed

34.

Zhang D, Snyder AZ, Fox MD, Sansbury MW, Shimony JS, Raichle ME. Intrinsic functional relations between human cerebral cortex and thalamus. J Neurophysiol 2008, 100: 1740–1748.CrossRefPubMedPubMedCentral

35.

Zhang D, Snyder AZ, Shimony JS, Fox MD, Raichle ME. Noninvasive functional and structural connectivity mapping of the human thalamocortical system. Cereb Cortex 2010, 20: 1187–1194.CrossRefPubMed

Titel: Altered Resting-State Signals in Patients with Acute Stroke In or Under the Thalamus
verfasst von: Lijun Chen
Chuanfu Li
Jian Zhai
Anqin Wang
Qin Song
Ying Liu
Ru Ma
Long Han
Yamikani Ndasauka
Xiaoming Li
Hai Li
Xiaochu Zhang
Publikationsdatum: 01.12.2016
Verlag: Springer Singapore
Erschienen in: Neuroscience Bulletin / Ausgabe 6/2016
Print ISSN: 1673-7067
Elektronische ISSN: 1995-8218
DOI: https://doi.org/10.1007/s12264-016-0064-3

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