Erschienen in:
01.07.2010 | Case Report
An unusual association: anti-Jo1 and anti-SRP antibodies in the serum of a patient with polymyositis
verfasst von:
Melinda Vincze, Peter A. Molnár, Judit Tumpek, Lászlóné Szőllősi, Ágnes Gyetvai, Anikó Kapitány, Katalin Dankó
Erschienen in:
Clinical Rheumatology
|
Ausgabe 7/2010
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Abstract
The idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by chronic inflammation, resulting in the progressive weakness of the proximal muscles. Myositis-specific or myositis-associated autoantibodies can often be found in serum of polymyositis and dermatomyositis patients. This autoantibody presence may play a significant role in patient diagnosis and classification. We present a female polymyositis patient characterized with serious muscle weakness and lung involvement. Anti-Jo1 antibodies were detected in the patient’s serum at the time of diagnosis. After 5 years of treatment and surveillance, recent laboratory analysis showed the presence anti-SRP antibody in her serum.