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Journal of Nuclear Cardiology

Erschienen in:

01.02.2017 | Editorial

Anthracycline-induced cardiomyopathy: The search continues

verfasst von: Agnes S. Kim, MD, PhD, Steven R. Bergmann, MD, PhD

Erschienen in: Journal of Nuclear Cardiology | Ausgabe 1/2017

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Excerpt

Anthracyclines are not only some of the most effective, but also the most toxic, chemotherapeutic agents. Their use is associated with a dose-dependent, progressive, dilated cardiomyopathy. To date, there is no specific laboratory or imaging approach to proactively identify patients who will develop anthracycline-induced cardiotoxicity. Echocardiography and radionuclide ventriculography have been employed to measure left ventricular ejection fraction as chemotherapy progresses, and once decreases in function are identified, chemotherapy dosage or frequency is modified, or the chemotherapy is stopped. Unfortunately, overt cardiomyopathy is a late manifestation of injury due to anthracyclines,1 and thus prediction of which patients may develop anthracycline-induced cardiac toxicity is an important goal, especially since these agents are frequently used in children and young adults. …

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Titel: Anthracycline-induced cardiomyopathy: The search continues
verfasst von: Agnes S. Kim, MD, PhD
Steven R. Bergmann, MD, PhD
Publikationsdatum: 01.02.2017
Verlag: Springer US
Erschienen in: Journal of Nuclear Cardiology / Ausgabe 1/2017
Print ISSN: 1071-3581
Elektronische ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-015-0352-8

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