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Journal of Natural Medicines

Erschienen in:

01.10.2008 | Note

Anti-inflammatory effect of Pinus sibirica oil extract in animal models

verfasst von: Alexander N. Shikov, Olga N. Pozharitskaya, Valery G. Makarov, Marina N. Makarova

Erschienen in: Journal of Natural Medicines | Ausgabe 4/2008

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Abstract

The anti-inflammatory effect of the oil extract of seeds of Pinus sibirica Du Tour was evaluated and compared with phenylbutazone. Oral administration of this extract at a dose of 300 mg/kg showed anti-inflammatory activity in the carrageenin-induced edema test in rats. In addition, P. sibirica oil extract showed analgesic properties in the hot-plate test and antipyretic properties in adjuvant-induced local hyperthermia, both in rats. In conclusion, these results provide evidence for the potential usefulness of P. sibirica oil extract, a defined mixture of long-chain polyunsaturated fatty acids, sterols, tocopherols and polyphenols, in inflammatory disorders.

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Titel: Anti-inflammatory effect of Pinus sibirica oil extract in animal models
verfasst von: Alexander N. Shikov
Olga N. Pozharitskaya
Valery G. Makarov
Marina N. Makarova
Publikationsdatum: 01.10.2008
Verlag: Springer Japan
Erschienen in: Journal of Natural Medicines / Ausgabe 4/2008
Print ISSN: 1340-3443
Elektronische ISSN: 1861-0293
DOI: https://doi.org/10.1007/s11418-008-0254-z

Springer Medizin

Abstract

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