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Journal of Natural Medicines

Journal of Natural Medicines OnlineFirst articles

09.01.2019 | Original Paper

Anti-proliferative effect of auriculataoside A on B16 melanoma 4A5 cells by suppression of Cdc42–Rac1–RhoA signaling protein levels

Auriculataoside A, an anthracenone dimer glycoside isolated from Cassia auriculata seed, shows anti-proliferative effects on cell line B16 melanoma 4A5 cells with an IC50 value of 0.82 μM. However, it shows no such effect on normal human dermal …

07.01.2019 | Original Paper

Andrographolide impairs alpha-naphthylisothiocyanate-induced cholestatic liver injury in vivo

To investigate if andrographolide impairs cholestatic liver injury. All rats were randomly divided into six groups—(1) control (n = 6), (2) control + 200 mg/kg andrographolide (n = 6), (3) alpha-naphthylisothiocyanate (ANIT)-control (n = 6), (4) …

01.01.2019 | Original Paper

Simultaneous quantitative analysis of 11 flavonoid derivatives with a single marker in persimmon leaf extraction and evaluation of their myocardium protection activity

An improved, reliable and comprehensive method for assessing the quality of the ethyl acetate extract from persimmon leaves (EAPL) and its commercial preparation, Naoxinqing (Brain and Heart Clear capsules), has been developed and validated. Based …

14.12.2018 | Note

Endophyte composition and Cinchona alkaloid production abilities of Cinchona ledgeriana cultivated in Japan

New eight endophytic filamentous fungi were isolated from the young stems of Cinchona ledgeriana (Rubiaceae) cultivated in Japan. They were classified into four genera based on phylogenetic analysis of the nucleotide sequences of the internal …

13.12.2018 | Original Paper Open Access

Identification of potential genes involved in triterpenoid saponins biosynthesis in Gleditsia sinensis by transcriptome and metabolome analyses

Gleditsia sinensis is widely used as a medicinal plant in Asia, especially in China. Triterpenes, alkaloids, and sterols were isolated from Gleditsia species. Among them, triterpenoid saponins are very important metabolites owing to their various …

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The Journal of Natural Medicines is an international journal presenting original research in naturally occurring medicines and their related foods and cosmetics. It covers

chemistry of natural products; biochemistry of medicinal plants; pharmacology of natural products and herbs, including Kampo formulas and traditional herbs; botanical anatomy; cultivation of medicinal plants.

The journal publishes Reviews, Mini-Reviews, Original Papers, Notes, Rapid Communications and Natural Resource Letters.

Of the papers published in each volume of the Journal of Natural Medicines, approximately three will be chosen by members of the Selection Committee for honors as the Journal of Natural Medicines Award.

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