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Erschienen in: Clinical Orthopaedics and Related Research® 4/2014

01.04.2014 | Clinical Research

Are Younger Patients Undergoing TKAs Appropriately Characterized As Active?

verfasst von: James A. Keeney, MD, Ryan M. Nunley, MD, Rick W. Wright, MD, Robert L. Barrack, MD, John C. Clohisy, MD

Erschienen in: Clinical Orthopaedics and Related Research® | Ausgabe 4/2014

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Abstract

Background

The use of TKAs in young patients is increasing. Demographic characteristics and activity levels among this patient group may affect implant selection, performance, and survivorship. Patient age (≤ 55 years) and preoperative diagnosis have been used to define this patient group, with the presumption that these patients are more active than older patients with similar indications for TKA.

Questions/purposes

We questioned whether (1) demographic features of young patients support high activity expectations after TKA, and (2) preoperative or postoperative functional activity measures support projections that young patients are active after TKA.

Methods

We retrospectively compared demographic characteristics (gender, BMI, diagnosis) and functional activity profile (as determined by preoperative and postoperative UCLA activity score and functional subscores of The Knee Society and WOMAC instruments) for 150 patients 55 years old or younger (181 TKAs) and 262 patients who were between 65 to 75 years old (314 TKAs) at the time of surgery.

Results

Younger patients having TKAs were significantly more likely than older patients to be female (74% versus 60%, p < 0.001) and to have diagnoses other than osteoarthritis (18% versus 3%, p < 0.001). BMI was significantly greater among younger female patients than among other age and gender combinations (35 kg/m2 versus 31 kg/m2, p < 0.001). Male patients had higher mean postoperative UCLA activity scores (5.5 versus 4.4, p < 0.001), Knee Society function subscores (80.2 versus 66.4, p < 0.001), and WOMAC function subscores (82.8 versus 74.2, p < 0.01) compared with female patients, but these were not different in older versus younger patients.

Conclusions

Sustained high activity levels are not likely to be a principal cause of revision TKAs among younger patients when considering age and diagnosis alone. Determining the effect of activity on survivorship of prosthetic designs and techniques should be based on measured functional activity instead of using age and diagnosis as surrogates for activity.

Level of Evidence

Level III, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.
Literatur
1.
Zurück zum Zitat Amstutz HC, Thomas BJ, Jinnah R, Kim W, Grogan T, Yale C. Treatment of primary osteoarthritis of the hip: a comparison of total joint and surface replacement arthroplasty. J Bone Joint Surg Am. 1984;66:228–241.PubMed Amstutz HC, Thomas BJ, Jinnah R, Kim W, Grogan T, Yale C. Treatment of primary osteoarthritis of the hip: a comparison of total joint and surface replacement arthroplasty. J Bone Joint Surg Am. 1984;66:228–241.PubMed
2.
Zurück zum Zitat Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15:1833–1840.PubMed Bellamy N, Buchanan WW, Goldsmith CH, Campbell J, Stitt LW. Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee. J Rheumatol. 1988;15:1833–1840.PubMed
3.
Zurück zum Zitat Bozic KJ, Kurtz SM, Lau E, Ong K, Chiu V, Vail TP, Rubash HE, Berry DJ. The epidemiology of revision total knee arthroplasty in the United States. Clin Orthop Relat Res. 2010; 468: 45–51.PubMedCentralPubMedCrossRef Bozic KJ, Kurtz SM, Lau E, Ong K, Chiu V, Vail TP, Rubash HE, Berry DJ. The epidemiology of revision total knee arthroplasty in the United States. Clin Orthop Relat Res. 2010; 468: 45–51.PubMedCentralPubMedCrossRef
4.
Zurück zum Zitat Clohisy JC, Kamath GV, Byrd GD, Steger-May K, Wright RW. Patient compliance with clinical follow-up after total joint arthroplasty. J Bone Joint Surg Am. 2008;90:1848–1854.PubMedCrossRef Clohisy JC, Kamath GV, Byrd GD, Steger-May K, Wright RW. Patient compliance with clinical follow-up after total joint arthroplasty. J Bone Joint Surg Am. 2008;90:1848–1854.PubMedCrossRef
5.
Zurück zum Zitat Crowder AR, Duffy GP, Trousdale RT. Long-term results of total knee arthroplasty in young patients with rheumatoid arthritis. J Arthroplasty. 2005;20(7 suppl 3):12–16.PubMedCrossRef Crowder AR, Duffy GP, Trousdale RT. Long-term results of total knee arthroplasty in young patients with rheumatoid arthritis. J Arthroplasty. 2005;20(7 suppl 3):12–16.PubMedCrossRef
6.
Zurück zum Zitat Dalury DF, Ewald FC, Christie MJ, Scott RD. Total knee arthroplasty in a group of patients less than 45 years of age. J Arthroplasty. 1995;10:598–602.PubMedCrossRef Dalury DF, Ewald FC, Christie MJ, Scott RD. Total knee arthroplasty in a group of patients less than 45 years of age. J Arthroplasty. 1995;10:598–602.PubMedCrossRef
7.
Zurück zum Zitat Diduch DR, Insall JN, Scott WN, Scuderi GR, Font-Rodriguez D. Total knee replacement in young, active patients: long-term follow-up and functional outcome. J Bone Joint Surg Am. 1997;79:575–582.PubMed Diduch DR, Insall JN, Scott WN, Scuderi GR, Font-Rodriguez D. Total knee replacement in young, active patients: long-term follow-up and functional outcome. J Bone Joint Surg Am. 1997;79:575–582.PubMed
8.
Zurück zum Zitat Dowsey MM, Choong PF. Obesity is a major risk factor for prosthetic infection after primary hip arthroplasty. Clin Orthop Relat Res. 2008;466:153–158.PubMedCentralPubMedCrossRef Dowsey MM, Choong PF. Obesity is a major risk factor for prosthetic infection after primary hip arthroplasty. Clin Orthop Relat Res. 2008;466:153–158.PubMedCentralPubMedCrossRef
9.
Zurück zum Zitat Duffy GP, Berry DJ, Rand JA. Cement versus cementless fixation in total knee arthroplasty. Clin Orthop Relat Res. 1998;356:66–72.PubMedCrossRef Duffy GP, Berry DJ, Rand JA. Cement versus cementless fixation in total knee arthroplasty. Clin Orthop Relat Res. 1998;356:66–72.PubMedCrossRef
10.
Zurück zum Zitat Duffy GP, Crowder AR, Trousdale RR, Berry DJ. Cemented total knee arthroplasty using a modern prosthesis in young patients with osteoarthritis. J Arthroplasty. 2007;22(6 suppl 2):67–70.PubMedCrossRef Duffy GP, Crowder AR, Trousdale RR, Berry DJ. Cemented total knee arthroplasty using a modern prosthesis in young patients with osteoarthritis. J Arthroplasty. 2007;22(6 suppl 2):67–70.PubMedCrossRef
11.
Zurück zum Zitat Ewald FC. The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clin Orthop Relat Res. 1989;248:9–12.PubMed Ewald FC. The Knee Society total knee arthroplasty roentgenographic evaluation and scoring system. Clin Orthop Relat Res. 1989;248:9–12.PubMed
12.
Zurück zum Zitat Gill GS, Chan KC, Mills DM. 5- to 18-year follow-up study of cemented total knee arthroplasty for patients 55 years old or younger. J Arthroplasty. 1997;12:49–54.PubMedCrossRef Gill GS, Chan KC, Mills DM. 5- to 18-year follow-up study of cemented total knee arthroplasty for patients 55 years old or younger. J Arthroplasty. 1997;12:49–54.PubMedCrossRef
13.
Zurück zum Zitat Gioe TJ, Novak C, Sinner P, Ma W, Mehle S. Knee arthroplasty in the young patient: survival in a community registry. Clin Orthop Relat Res. 2007;464:83–87.PubMed Gioe TJ, Novak C, Sinner P, Ma W, Mehle S. Knee arthroplasty in the young patient: survival in a community registry. Clin Orthop Relat Res. 2007;464:83–87.PubMed
14.
Zurück zum Zitat Harrysson OL, Robertsson O, Nayfeh JF. Higher cumulative revision rate of knee arthroplasties in younger patients with osteoarthritis. Clin Orthop Relat Res. 2004;421:162–168.PubMedCrossRef Harrysson OL, Robertsson O, Nayfeh JF. Higher cumulative revision rate of knee arthroplasties in younger patients with osteoarthritis. Clin Orthop Relat Res. 2004;421:162–168.PubMedCrossRef
15.
Zurück zum Zitat Himanen AK, Belt E, Nevalainen J, Hamalainen M, Lehto MU. Survival of the AGC total knee arthroplasty is similar for arthrosis and rheumatoid arthritis: Finnish Arthroplasty Register report on 8,467 operations carried out between 1985 and 1999. Acta Orthop. 2005;76:85–88.PubMedCrossRef Himanen AK, Belt E, Nevalainen J, Hamalainen M, Lehto MU. Survival of the AGC total knee arthroplasty is similar for arthrosis and rheumatoid arthritis: Finnish Arthroplasty Register report on 8,467 operations carried out between 1985 and 1999. Acta Orthop. 2005;76:85–88.PubMedCrossRef
16.
Zurück zum Zitat Hungerford DS, Krackow KA, Kenna RV. Cementless total knee replacement in patients 50 years old and under. Orthop Clin North Am. 1989;20:131–145.PubMed Hungerford DS, Krackow KA, Kenna RV. Cementless total knee replacement in patients 50 years old and under. Orthop Clin North Am. 1989;20:131–145.PubMed
17.
Zurück zum Zitat Jamsen E, Nevalainen P, Eskelinen A, Huotari K, Kalliovalkama J, Moilanen T. Obesity, diabetes, and preoperative hyperglycemia as predictors of periprosthetic joint infection: a single-center analysis of 7181 primary hip and knee replacements for osteoarthritis. J Bone Joint Surg Am. 2012;94:e101 1–9. Jamsen E, Nevalainen P, Eskelinen A, Huotari K, Kalliovalkama J, Moilanen T. Obesity, diabetes, and preoperative hyperglycemia as predictors of periprosthetic joint infection: a single-center analysis of 7181 primary hip and knee replacements for osteoarthritis. J Bone Joint Surg Am. 2012;94:e101 1–9.
18.
Zurück zum Zitat Hofmann AA, Heithoff SM, Camargo M. Cementless total knee arthroplasty in patients 50 years or younger. Clin Orthop Relat Res. 2002;404:102–107.PubMedCrossRef Hofmann AA, Heithoff SM, Camargo M. Cementless total knee arthroplasty in patients 50 years or younger. Clin Orthop Relat Res. 2002;404:102–107.PubMedCrossRef
19.
Zurück zum Zitat Keeney JA, Eunice S, Pashos G, Wright RW, Clohisy JC. What is the evidence for total knee arthroplasty in young patients?: a systematic review of the literature. Clin Orthop Relat Res. 2011;469:574–583.PubMedCentralPubMedCrossRef Keeney JA, Eunice S, Pashos G, Wright RW, Clohisy JC. What is the evidence for total knee arthroplasty in young patients?: a systematic review of the literature. Clin Orthop Relat Res. 2011;469:574–583.PubMedCentralPubMedCrossRef
20.
Zurück zum Zitat Koh IJ, Cho WS, Choi NY, Kim TK; The Kleos Korea Research Group. Causes, risk factors, and trends in failures after TKA in Korea over the past 5 years: a multicenter study. Clin Orthop Relat Res. 2013 Aug 28. [Epub ahead of print]. Koh IJ, Cho WS, Choi NY, Kim TK; The Kleos Korea Research Group. Causes, risk factors, and trends in failures after TKA in Korea over the past 5 years: a multicenter study. Clin Orthop Relat Res. 2013 Aug 28. [Epub ahead of print].
21.
Zurück zum Zitat Kurtz SM, Lau E, Ong K, Zhao K, Kelly M, Bozic KJ. Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030. Clin Orthop Relat Res. 2009;467:2606–2612.PubMedCentralPubMedCrossRef Kurtz SM, Lau E, Ong K, Zhao K, Kelly M, Bozic KJ. Future young patient demand for primary and revision joint replacement: national projections from 2010 to 2030. Clin Orthop Relat Res. 2009;467:2606–2612.PubMedCentralPubMedCrossRef
22.
Zurück zum Zitat Lonner JH, Hershman S, Mont M, Lotke PA. Total knee arthroplasty in patients 40 years of age and younger with osteoarthritis. Clin Orthop Relat Res. 2000;380:85–90.PubMedCrossRef Lonner JH, Hershman S, Mont M, Lotke PA. Total knee arthroplasty in patients 40 years of age and younger with osteoarthritis. Clin Orthop Relat Res. 2000;380:85–90.PubMedCrossRef
23.
Zurück zum Zitat Malinzak RA, Ritter MA, Berend ME, Meding JB, Olberding EM, Davis KE. Morbidly obese, diabetic, younger, and unilateral joint arthroplasty patients have elevated total joint arthroplasty infection rates. J Arthroplasty. 2009;24:84–88.PubMedCrossRef Malinzak RA, Ritter MA, Berend ME, Meding JB, Olberding EM, Davis KE. Morbidly obese, diabetic, younger, and unilateral joint arthroplasty patients have elevated total joint arthroplasty infection rates. J Arthroplasty. 2009;24:84–88.PubMedCrossRef
24.
Zurück zum Zitat Mont MA, Sayeed SA, Osuji O, Johnson AJ, Naziri Q, Delanois RE, Bonutti PM. Total knee arthroplasty in patients 40 years and younger. J Knee Surg. 2012;25:65–69.PubMedCrossRef Mont MA, Sayeed SA, Osuji O, Johnson AJ, Naziri Q, Delanois RE, Bonutti PM. Total knee arthroplasty in patients 40 years and younger. J Knee Surg. 2012;25:65–69.PubMedCrossRef
25.
Zurück zum Zitat Odland AN, Callaghan JJ, Liu SS, Wells CW. Wear and lysis is the problem in modular TKA in the young OA patient at 10 years. Clin Orthop Relat Res. 2011;469:41–47.PubMedCentralPubMedCrossRef Odland AN, Callaghan JJ, Liu SS, Wells CW. Wear and lysis is the problem in modular TKA in the young OA patient at 10 years. Clin Orthop Relat Res. 2011;469:41–47.PubMedCentralPubMedCrossRef
26.
Zurück zum Zitat Pennington DW, Swienckowski JJ, Lutes WB, Drake GN. Unicompartmental knee arthroplasty in patients sixty years of age or younger. J Bone Joint Surg Am. 2003;85:1968–1973.PubMed Pennington DW, Swienckowski JJ, Lutes WB, Drake GN. Unicompartmental knee arthroplasty in patients sixty years of age or younger. J Bone Joint Surg Am. 2003;85:1968–1973.PubMed
27.
Zurück zum Zitat Ranawat CS, Padgett DE, Ohashi Y. Total knee arthroplasty for patients younger than 55 years. Clin Orthop Relat Res. 1989;248:27–33.PubMed Ranawat CS, Padgett DE, Ohashi Y. Total knee arthroplasty for patients younger than 55 years. Clin Orthop Relat Res. 1989;248:27–33.PubMed
28.
Zurück zum Zitat Rand JA, Trousdale RT, Ilstrup DM, Harmsen WS. Factors affecting the durability of primary total knee prostheses. J Bone Joint Surg Am. 2003;85:259–265.PubMed Rand JA, Trousdale RT, Ilstrup DM, Harmsen WS. Factors affecting the durability of primary total knee prostheses. J Bone Joint Surg Am. 2003;85:259–265.PubMed
29.
Zurück zum Zitat Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME, Malinzak RA. The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am. 2011;93:1588–1596.PubMedCrossRef Ritter MA, Davis KE, Meding JB, Pierson JL, Berend ME, Malinzak RA. The effect of alignment and BMI on failure of total knee replacement. J Bone Joint Surg Am. 2011;93:1588–1596.PubMedCrossRef
30.
Zurück zum Zitat Ritter MA, Lutgring JD, Davis KE, Faris PM, Berend ME. Total knee arthroplasty effectiveness in patients 55 years old and younger: osteoarthritis vs. rheumatoid arthritis. Knee. 2007;14:9–11.PubMedCrossRef Ritter MA, Lutgring JD, Davis KE, Faris PM, Berend ME. Total knee arthroplasty effectiveness in patients 55 years old and younger: osteoarthritis vs. rheumatoid arthritis. Knee. 2007;14:9–11.PubMedCrossRef
31.
Zurück zum Zitat Sharkey PF, Hozack WJ, Rothman RH, Shastri S, Jacoby SM. Insall Award paper: Why are total knee arthroplasties failing today? Clin Orthop Relat Res. 2002;404:7–13.PubMedCrossRef Sharkey PF, Hozack WJ, Rothman RH, Shastri S, Jacoby SM. Insall Award paper: Why are total knee arthroplasties failing today? Clin Orthop Relat Res. 2002;404:7–13.PubMedCrossRef
32.
Zurück zum Zitat Stern SH, Bowen MK, Insall JN, Scuderi GR. Cemented total knee arthroplasty for gonarthrosis in patients 55 years old or younger. Clin Orthop Relat Res. 1990;260:124–129.PubMed Stern SH, Bowen MK, Insall JN, Scuderi GR. Cemented total knee arthroplasty for gonarthrosis in patients 55 years old or younger. Clin Orthop Relat Res. 1990;260:124–129.PubMed
33.
Zurück zum Zitat Stuart MJ, Rand JA. Total knee arthroplasty in young adults who have rheumatoid arthritis. J Bone Joint Surg Am. 1988;70:84–87.PubMed Stuart MJ, Rand JA. Total knee arthroplasty in young adults who have rheumatoid arthritis. J Bone Joint Surg Am. 1988;70:84–87.PubMed
34.
Zurück zum Zitat Tai CC, Cross MJ. Five- to 12-year follow-up of a hydroxyapatite-coated, cementless total knee replacement in young, active patients. J Bone Joint Surg Br. 2006;88:1158–1163.PubMedCrossRef Tai CC, Cross MJ. Five- to 12-year follow-up of a hydroxyapatite-coated, cementless total knee replacement in young, active patients. J Bone Joint Surg Br. 2006;88:1158–1163.PubMedCrossRef
36.
Zurück zum Zitat World Health Organization, Division of Noncommunicable Diseases, World Health Organization, Programme of Nutrition, Family and Reproductive Health. Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation on Obesity. Geneva, Switzerland; 1998:29. Available at: http://apps.who.int/iris/handle/10665/63854. Accessed October 30, 2013. World Health Organization, Division of Noncommunicable Diseases, World Health Organization, Programme of Nutrition, Family and Reproductive Health. Obesity: Preventing and Managing the Global Epidemic: Report of a WHO Consultation on Obesity. Geneva, Switzerland; 1998:29. Available at: http://​apps.​who.​int/​iris/​handle/​10665/​63854. Accessed October 30, 2013.
Metadaten
Titel
Are Younger Patients Undergoing TKAs Appropriately Characterized As Active?
verfasst von
James A. Keeney, MD
Ryan M. Nunley, MD
Rick W. Wright, MD
Robert L. Barrack, MD
John C. Clohisy, MD
Publikationsdatum
01.04.2014
Verlag
Springer US
Erschienen in
Clinical Orthopaedics and Related Research® / Ausgabe 4/2014
Print ISSN: 0009-921X
Elektronische ISSN: 1528-1132
DOI
https://doi.org/10.1007/s11999-013-3376-x

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