Erschienen in:
01.12.2015 | Original Paper
Arterial stiffness as a predictor of recovery of left ventricular systolic function after acute myocardial infarction treated with primary percutaneous coronary intervention
verfasst von:
Egidio Imbalzano, Marco Vatrano, Giuseppe Mandraffino, Lorenzo Ghiadoni, Sebastiano Gangemi, Rosa Maria Bruno, Vincenzo Antonio Ciconte, Nevena Paunovic, Rossella Costantino, Enrico Maria Mormina, Roberto Ceravolo, Antonino Saitta, Giuseppe Dattilo
Erschienen in:
The International Journal of Cardiovascular Imaging
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Ausgabe 8/2015
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Abstract
Left ventricular ejection fraction (LVEF) and pulse wave velocity (PWV) are acknowledged as independent risk factors in different high-risk populations. We investigated the effects of arterial stiffness on LV function at 3 and 6 months after acute myocardial infarction. Changes in LVEF were evaluated in 136 consecutive patients who were diagnosed with ST-segment elevation coronary syndrome and treated with primary percutaneous coronary intervention. Doppler guided by 2D ultrasound was used to measure carotid-femoral PWV. According to tertiles of arterial stiffness, a significant correlation between higher PWV and worse recovery in LVEF was found (3 months EF change: 9.9 ± 5.0 % vs 5.9 ± 3.4 vs 3.8 ± 1.6; p < 0.001 and 6 months EF change: 18.5 ± 7.0 % vs 11.5 ± 5.2 vs 7.3 ± 3.0; p = 0.002). In the multivariate analysis PWV showed the ability to predict the outcome in terms of EF recovery at 3 and 6 months also after any correction for age and other variables (β = −0.566, p < 0.001). Arterial stiffening may result in a less effective recovery of LV function after acute myocardial infarction.