Erschienen in:
01.09.2020 | ASO Author Reflections
ASO Author Reflections: Sequential Decision Tree Analysis Reveals Pivotal Branch Points in Predicting Implant-Based Reconstruction Failure Outcomes
verfasst von:
Jie Jane Chen, MD, Kathleen C. Horst, MD
Erschienen in:
Annals of Surgical Oncology
|
Ausgabe 3/2021
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Excerpt
The incidence of postmastectomy breast reconstruction has increased steadily since 2000, with a shift in patient preferences from autologous tissue reconstruction to implant-based reconstruction.
1 Compared with autologous tissue reconstruction, implant-based reconstruction is associated with an increased risk of complications, such as capsular contracture, infection, and implant rupture.
2 Radiation therapy (RT) may further increase the risk of these complications.
3 While there have been significant breakthroughs and technological advances in surgical and RT techniques related to breast reconstruction and oncologic treatment, there has not been a similar trend of increased clarity surrounding the impacts of the timing of postmastectomy RT on reconstruction failure outcomes. Overall, predicting the risk of implant-based reconstruction is an imperfect science. To elucidate complications and predictors of postmastectomy implant-based reconstruction failure to help guide clinical decision making, we performed a retrospective cohort study and developed a decision tree to sequentially analyze risk for reconstruction failure.
4 …