Erschienen in:
23.04.2019 | ASO Author Reflections
ASO Author Reflections: Splenic Hilar Nodal Dissection for Proximal Advanced Gastric Cancer
verfasst von:
Masahiro Yura, MD, Takaki Yoshikawa, MD, PhD
Erschienen in:
Annals of Surgical Oncology
|
Sonderheft 3/2019
Einloggen, um Zugang zu erhalten
Excerpt
Globally, D2 gastrectomy is an accepted surgical procedure for locally advanced gastric cancer. In Japan, total gastrectomy with splenectomy is performed for complete removal of the splenic hilar lymph nodes (LNs), defined as the #10 station according to the classification used by the Japanese Gastric Cancer Association (JGCA).
1 Recently, the Japan Clinical Oncology Group conducted a phase 3 study (JCOG0110) that compared splenectomy with spleen-preserving surgery and confirmed the survival noninferiority of spleen-preserving surgery versus splenectomy for advanced proximal gastric cancers not invading the greater curvature.
2 However, the optimal surgery for tumors involving the greater curvature remains unclear. The therapeutic efficacy of splenic hilar nodal dissection has not been fully evaluated, and the Japanese guideline states that the effect of splenectomy on advanced proximal gastric cancer invading the greater curvature is unknown. …