Background
Methods
Study design and subjects
Measurement of TCM constitution types
Determination of clinical data and laboratory parameters
Determination of serum cytokines levels
Statistical analysis
Results
Characteristics of the patients
TCM constitutional types
Age | Male (%) | BMI (Kg/m2) | FPI (mu/L) | TC (mmol/L) | TG (mmol/L) | Scr (μmol/L) | BUN (mg/dL) | |
---|---|---|---|---|---|---|---|---|
Qi-deficiency | ||||||||
Yes (n = 39) | 52 (49–54) | 18 (46.2) | 27.7 (26.3–28.9) | 14.3 (13.1–16.3) | 5.3 (4.8–5.8) | 2.5 (2.3–2.7) | 113 (96–133) | 14.0 (12.6–15.7) |
No (n = 267) | 52 (49–55) | 147 (55.1) | 26.9 (25.4–28.1) | 13.5 (11.8–15.9) | 4.8 (4.1–5.5) | 2.3 (1.8–2.8) | 110 (93–126) | 113.8 (12.9–15.1) |
P value | 0.825 | 0.308 | 0.026 | 0.030 | 0.002 | 0.011 | 0.482 | 0.627 |
Phlegm-damp | ||||||||
Yes (n = 57) | 52 (49–55) | 34 (59.6) | 27.3 (26.0–28.8) | 14.7 (12.6–16.5) | 5.2 (4.6–5.6) | 2.5 (2.2–2.8) | 117 (100–137) | 14.6 (13.4–15.5) |
No (n = 249) | 52 (49–55) | 131 (52.6) | 26.9 (25.4–28.1) | 13.6 (11.8–15.8) | 4.8 (4.1–5.5) | 2.3 (1.8–2.7) | 109 (92–125) | 13.8 (12.8–14.9) |
P value | 0.640 | 0.378 | 0.029 | 0.054 | 0.014 | 0.029 | 0.024 | 0.013 |
Damp-heat | ||||||||
Yes (n = 52) | 51 (48–54) | 31 (59.6) | 27.6 (26.5–28.6) | 14.9 (13.1–16.4) | 5.3 (4.6–5.7) | 2.5 (2.2–2.9) | 118 (109–135) | 14.7 (13.2–15.5) |
No (n = 254) | 52 (49–55) | 134 (52.8) | 26.8 (25.3–28.2) | 13.5 (11.8–15.8) | 4.8 (4.1–5.5) | 2.3 (1.8–2.7) | 108 (89–125) | 13.8 (12.8–14.9) |
P value | 0.081 | 0.446 | 0.013 | 0.021 | 0.029 | 0.010 | 0.001 | 0.018 |
Associations of body constitution with insulin resistance factors
Incidence of diabetes in IGR patients according to body constitution
Diabetes | Nondiabetes | P value | |
---|---|---|---|
Qi-deficiency | |||
Yes (n = 39) | 8 (20.5%) | 31 (79.5%) | 0.662 |
No (n = 267) | 48 (18.0%) | 219 (82.0%) | |
Phlegm-damp | |||
Yes (n = 57) | 18 (31.6%) | 39 (68.4%) | 0.007 |
No (n = 249) | 38 (15.3%) | 211 (84.75) | |
Damp-heat | |||
Yes (n = 52) | 17 (32.7%) | 35 (67.3%) | 0.005 |
No (n = 254) | 39 (15.4%) | 215 (84.6%) |
TCM body constitution may be a predictive factor for diabetes
Variable | Odds Ratio | 95% Confidence Interval | P value |
---|---|---|---|
FPI | 1.133 | 1.016 to 1.264 | 0.025 |
TC | 1.430 | 1.017 to 2.011 | 0.039 |
Scr | 1.014 | 1.001 to 1.026 | 0.032 |
Phlegm-damp | 2.846 | 1.345 to 6.022 | 0.006 |
Damp-heat | 3.080 | 1.443 to 6.574 | 0.004 |