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01.02.2009 | Review

Bench-to-bedside review: Ventilatory abnormalities in sepsis

verfasst von: Sheldon Magder

Erschienen in: Critical Care | Ausgabe 1/2009

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Abstract

In septic patients increased central drive and increased metabolic demands combine to increase energy demands on the ventilatory muscles. This occurs at a time when energy supplies are limited and energy production hindered, and it leads to an energy supply-demand imbalance and often ventilatory failure. Problems related to contractile function of the ventilatory muscles also contribute, especially when the clinical course is prolonged. The increased ventilatory activity increases interactions between the ventilatory and cardiovascular systems, and when ventilatory muscles fail and mechanical ventilatory support is required a new set of problems emerges. In this review I discuss factors related to ventilatory muscle failure, giving emphasis to mechanical and supply demand aspects. I also review the implications of changes in ventilatory patterns for heart-lung interactions.

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Titel: Bench-to-bedside review: Ventilatory abnormalities in sepsis
verfasst von: Sheldon Magder
Publikationsdatum: 01.02.2009
Verlag: BioMed Central
Erschienen in: Critical Care / Ausgabe 1/2009
Elektronische ISSN: 1364-8535
DOI: https://doi.org/10.1186/cc7116

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Novel polymorphism of interleukin-18 associated with greater inflammation after cardiac surgery

Extending the role of lactate measurement into the prehospital environment

Computer says 2.5 litres – how best to incorporate intelligent software into clinical decision making in the intensive care unit?

Neu im Fachgebiet AINS

Hinter dieser Appendizitis steckte ein Erreger

Ärztliche Empathie hilft gegen Rückenschmerzen

Mehr Schaden als Nutzen durch präoperatives Aussetzen von GLP-1-Agonisten?

S3-Leitlinie zu Pankreaskrebs aktualisiert

Update AINS