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Erschienen in: Pediatric Cardiology 2/2013

01.02.2013 | Original Article

Beneficial Effects of Residual Right Ventricular Outflow Tract Obstruction on Right Ventricular Volume and Function in Patients After Repair of Tetralogy of Fallot

verfasst von: Heiner Latus, Kerstin Gummel, Stefan Rupp, Klaus Valeske, Hakan Akintuerk, Christian Jux, Juergen Bauer, Dietmar Schranz, Christian Apitz

Erschienen in: Pediatric Cardiology | Ausgabe 2/2013

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Abstract

Preservation of the pulmonary valve, even at the expense of a mild residual stenosis, is the current surgical policy for the management of patients with tetralogy of Fallot (TOF). This study aimed to assess the long-term effect of a residual right ventricular outflow tract obstruction (RVOTO) on RV dimension and function. This study prospectively assessed 53 children (mean age, 13.4 ± 6.4 years) after repair of TOF using cardiovascular magnetic resonance imaging. Residual RVOTO on echocardiography was defined as a peak systolic RVOT gradient of 25 mmHg or higher. Patients with RVOTO (n = 29) had significantly less pulmonary regurgitation (25.2 ± 10.6 %) than patients without RVOTO (30.8 ± 9.3 %; p = 0.05) (n = 24). Compared with patients who had no RVOTO, children with RVOTO had significantly smaller RV end-diastolic volume (94.0 ± 2.6 vs 104.0 ± 20.7 ml/m2; p < 0.05) and end-systolic volume (42.9 ± 20.0 vs 48.9 ± 13.2 ml/m2; p < 0.05), whereas RV ejection fraction did not differ significantly between the two groups (55.5 ± 8.4 vs 54.0 ± 6.6 %). Restrictive physiology, assessed by late diastolic forward flow in the main pulmonary artery, was equally distributed within the two groups (31 vs 25 %; nonsignificant difference). According to the study data, residual RVOTO after repair of TOF does not affect RV function, whereas RV dimensions and the degree of pulmonary regurgitation are more favorable in the long-term follow-up evaluation of those patients. These results confirm the beneficial effects of the current strategy for repair of TOF.
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Metadaten
Titel
Beneficial Effects of Residual Right Ventricular Outflow Tract Obstruction on Right Ventricular Volume and Function in Patients After Repair of Tetralogy of Fallot
verfasst von
Heiner Latus
Kerstin Gummel
Stefan Rupp
Klaus Valeske
Hakan Akintuerk
Christian Jux
Juergen Bauer
Dietmar Schranz
Christian Apitz
Publikationsdatum
01.02.2013
Verlag
Springer-Verlag
Erschienen in
Pediatric Cardiology / Ausgabe 2/2013
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-012-0476-4

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