Skip to main content
Erschienen in: European Spine Journal 5/2013

01.05.2013 | Original Article

Bone union rate with autologous iliac bone versus local bone graft in posterior lumbar interbody fusion (PLIF): a multicenter study

verfasst von: Zenya Ito, Shiro Imagama, Tokumi Kanemura, Yudo Hachiya, Yasushi Miura, Mitsuhiro Kamiya, Yasutsugu Yukawa, Yoshihito Sakai, Yoshito Katayama, Norimitsu Wakao, Yukihiro Matsuyama, Naoki Ishiguro

Erschienen in: European Spine Journal | Ausgabe 5/2013

Einloggen, um Zugang zu erhalten

Abstract

Purpose

The purpose of this study is to compare bone union rate between autologous iliac bone and local bone graft in patients treated by posterior lumbar interbody fusion (PLIF) using carbon cage for single level interbody fusion.

Methods

The subjects were 106 patients whose course could be observed for at least 2 years. The diagnosis was lumbar spinal canal stenosis in 46 patients, herniated lumbar disk in 12 patients and degenerative spondylolisthesis in 51 patients. Single interbody PLIF was done using iliac bone graft in 53 patients and local bone graft in 56 patients. Existence of pseudo-arthrosis on X-P (AP and lateral view) was investigated during the same follow up period.

Results

No significant differences were found in operation time and blood loss. Significant differences were also not observed in fusion grade at any follow up period or in fusion progression between the two groups. Donor site pain continued for more than 3 months in five cases (9 %). The final fusion rate was 96.3 versus 98.3 %.

Conclusions

Almost the same results in fusion were obtained from both the local bone group and the autologous iliac bone group. Fusion progression was almost the same. Complications at donor sites were seen in 19 % of the cases. From the above results, it was concluded that local bone graft is as beneficial as autologous iliac bone graft for PLIF at a single level.
Literatur
1.
Zurück zum Zitat An HS, Lynch K, Toth J (1995) Prospective comparison of autograft vs. allograft for adult posterolateral lumbar spine fusion: differences among freeze-dried, frozen, and mixed grafts. J Spinal Disord 8:131–135PubMedCrossRef An HS, Lynch K, Toth J (1995) Prospective comparison of autograft vs. allograft for adult posterolateral lumbar spine fusion: differences among freeze-dried, frozen, and mixed grafts. J Spinal Disord 8:131–135PubMedCrossRef
2.
Zurück zum Zitat Le Huec JC, Lesprit E, Delavigne C et al (1997) Tri-calcium phosphate ceramics and allografts as bone substitutes for spinal fusion in idiopathic scoliosis: comparative clinical results at four years. Acta Orthop Belg 63:202–211PubMed Le Huec JC, Lesprit E, Delavigne C et al (1997) Tri-calcium phosphate ceramics and allografts as bone substitutes for spinal fusion in idiopathic scoliosis: comparative clinical results at four years. Acta Orthop Belg 63:202–211PubMed
3.
Zurück zum Zitat Frenkel SR, Moskovich R, Spivak J et al (1993) Demineralized bone matrix. Enhancement of spinal fusion. Spine 18:1634–1639PubMedCrossRef Frenkel SR, Moskovich R, Spivak J et al (1993) Demineralized bone matrix. Enhancement of spinal fusion. Spine 18:1634–1639PubMedCrossRef
4.
Zurück zum Zitat Holliger EH, Trawick RH, Boden SD et al (1996) Morphology of the lumbar intertransverse process fusion mass in the rabbit model: a comparison between two bone graft materials-rhBMP-2 and autograft. J Spinal Disord 9:125–128PubMedCrossRef Holliger EH, Trawick RH, Boden SD et al (1996) Morphology of the lumbar intertransverse process fusion mass in the rabbit model: a comparison between two bone graft materials-rhBMP-2 and autograft. J Spinal Disord 9:125–128PubMedCrossRef
5.
Zurück zum Zitat Tay BK, Le AX, Heilman M et al (1998) Use of a collagen-hydroxyapatite matrix in spinal fusion. A rabbit model. Spine 23:2276–2281PubMedCrossRef Tay BK, Le AX, Heilman M et al (1998) Use of a collagen-hydroxyapatite matrix in spinal fusion. A rabbit model. Spine 23:2276–2281PubMedCrossRef
6.
Zurück zum Zitat Younger EM, Chapman MW (1989) Morbidity at bone graft donor sites. J Orthop Trauma 3:192–195PubMedCrossRef Younger EM, Chapman MW (1989) Morbidity at bone graft donor sites. J Orthop Trauma 3:192–195PubMedCrossRef
7.
Zurück zum Zitat Keller EE, Triplett WW (1987) Iliac bone grafting: review of 160 consecutive cases. J Oral Maxillofac Surg 45:11–14PubMedCrossRef Keller EE, Triplett WW (1987) Iliac bone grafting: review of 160 consecutive cases. J Oral Maxillofac Surg 45:11–14PubMedCrossRef
8.
Zurück zum Zitat Summers BN, Eisenstein SM (1989) Donor site pain from the ilium: a complication of lumbar spine fusion. J Bone Joint Surg Br 71:677–680PubMed Summers BN, Eisenstein SM (1989) Donor site pain from the ilium: a complication of lumbar spine fusion. J Bone Joint Surg Br 71:677–680PubMed
9.
Zurück zum Zitat Violas P, Chapuis M, Bracq H (2004) Local autograft bone in the surgical management of adolescent idiopathic scoliosis. Spine 29:189–192PubMedCrossRef Violas P, Chapuis M, Bracq H (2004) Local autograft bone in the surgical management of adolescent idiopathic scoliosis. Spine 29:189–192PubMedCrossRef
10.
Zurück zum Zitat Miura Y, Imagama S, Yoda M et al (2003) Is local bone viable as a source of bone graft in posterior lumbar interbody fusion? Spine 28:2386–2389PubMedCrossRef Miura Y, Imagama S, Yoda M et al (2003) Is local bone viable as a source of bone graft in posterior lumbar interbody fusion? Spine 28:2386–2389PubMedCrossRef
11.
Zurück zum Zitat Hashimoto T, Oha F, Shigenobu K et al (2001) Mid-term clinical results of Graf stabilization for lumbar degenerative pathologies: a minimum 2-year follow-up. Spine J 1:283–289PubMedCrossRef Hashimoto T, Oha F, Shigenobu K et al (2001) Mid-term clinical results of Graf stabilization for lumbar degenerative pathologies: a minimum 2-year follow-up. Spine J 1:283–289PubMedCrossRef
12.
Zurück zum Zitat Tsuchiya K, Bridwell KH, Kuklo TR et al (2006) Minimum 5-year analysis of L5-S1 fusion using sacropelvic fixation (bilateral S1 and iliac screws) for spinal deformity. Spine 31(3):303–308 Tsuchiya K, Bridwell KH, Kuklo TR et al (2006) Minimum 5-year analysis of L5-S1 fusion using sacropelvic fixation (bilateral S1 and iliac screws) for spinal deformity. Spine 31(3):303–308
13.
Zurück zum Zitat Ito Z, Matsuyama Y, Sakai Y et al (2010) Bone union rate with autologous iliac bone versus local bone graft in posterior lumbar interbody fusion. Spine 35(21):E1101–E1105 Ito Z, Matsuyama Y, Sakai Y et al (2010) Bone union rate with autologous iliac bone versus local bone graft in posterior lumbar interbody fusion. Spine 35(21):E1101–E1105
14.
Zurück zum Zitat Brantigan JW, Steffee AD, Lewis ML et al (2000) Lumbar interbody fusion using the Brantigan I/F cage for posterior lumbar interbody fusion and the variable pedicle screw placement system: two-year results from a Food and Drug Administration investigational device exemption clinical trial. Spine 25:1437–1446PubMedCrossRef Brantigan JW, Steffee AD, Lewis ML et al (2000) Lumbar interbody fusion using the Brantigan I/F cage for posterior lumbar interbody fusion and the variable pedicle screw placement system: two-year results from a Food and Drug Administration investigational device exemption clinical trial. Spine 25:1437–1446PubMedCrossRef
15.
Zurück zum Zitat Agazzi S, Reverdin A, May D (1999) Posterior lumbar interbody fusion with cages: an independent review of 71 cases. J Neurosurg 91:186–192PubMed Agazzi S, Reverdin A, May D (1999) Posterior lumbar interbody fusion with cages: an independent review of 71 cases. J Neurosurg 91:186–192PubMed
16.
Zurück zum Zitat Christensen FB, Hansen ES, Eiskjaer SP et al (2002) Circumferential lumbar spinal fusion with Brantigan cage versus posterolateral fusion with titanium Cotrel-Dubousset instrumentation: a prospective, randomized clinical study of 146 patients. Spine 27:2674–2683PubMedCrossRef Christensen FB, Hansen ES, Eiskjaer SP et al (2002) Circumferential lumbar spinal fusion with Brantigan cage versus posterolateral fusion with titanium Cotrel-Dubousset instrumentation: a prospective, randomized clinical study of 146 patients. Spine 27:2674–2683PubMedCrossRef
17.
Zurück zum Zitat Hashimoto T, Shigenobu K, Kanayama M et al (2002) Clinical results of single-level posterior lumbar interbody fusion using the Brantigan I/F carbon cage filled with a mixture of local morselized bone and bioactive ceramic granules. Spine 27:258–262PubMedCrossRef Hashimoto T, Shigenobu K, Kanayama M et al (2002) Clinical results of single-level posterior lumbar interbody fusion using the Brantigan I/F carbon cage filled with a mixture of local morselized bone and bioactive ceramic granules. Spine 27:258–262PubMedCrossRef
18.
Zurück zum Zitat Kim KS, Ki YT, Lee JC (2005) Radiological changes in the bone fusion site after posterior lumbar interbody fusion using carbon cages impacted with laminar bone chips: follow-up study over more than 4 years. Spine 30:655–660PubMedCrossRef Kim KS, Ki YT, Lee JC (2005) Radiological changes in the bone fusion site after posterior lumbar interbody fusion using carbon cages impacted with laminar bone chips: follow-up study over more than 4 years. Spine 30:655–660PubMedCrossRef
19.
Zurück zum Zitat Diedrich O, Perlick L, Schmitt O et al (2001) Radiographic characteristics on conventional radiographs after posterior lumbar interbody fusion: comparative study between radiotranslucent and radiopaque cages. J Spinal Disord 14:522–532PubMedCrossRef Diedrich O, Perlick L, Schmitt O et al (2001) Radiographic characteristics on conventional radiographs after posterior lumbar interbody fusion: comparative study between radiotranslucent and radiopaque cages. J Spinal Disord 14:522–532PubMedCrossRef
20.
Zurück zum Zitat Banwart JC, Asher MA, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity: a statistical evaluation. Spine 20:1055–1060 Banwart JC, Asher MA, Hassanein RS (1995) Iliac crest bone graft harvest donor site morbidity: a statistical evaluation. Spine 20:1055–1060
21.
Zurück zum Zitat Robertson PA, Wray AC (2001) Natural history of posterior iliac crest bone graft donation for spinal surgery: a prospective analysis of morbidity. Spine 26:1473–1476PubMedCrossRef Robertson PA, Wray AC (2001) Natural history of posterior iliac crest bone graft donation for spinal surgery: a prospective analysis of morbidity. Spine 26:1473–1476PubMedCrossRef
22.
Zurück zum Zitat Sengupta DK, Truumees E, Patel CK et al (2006) Outcome of local bone versus autogenous iliac crest bone graft in the instrumented posterolateral fusion of the lumbar spine. Spine 31:985–991 Sengupta DK, Truumees E, Patel CK et al (2006) Outcome of local bone versus autogenous iliac crest bone graft in the instrumented posterolateral fusion of the lumbar spine. Spine 31:985–991
Metadaten
Titel
Bone union rate with autologous iliac bone versus local bone graft in posterior lumbar interbody fusion (PLIF): a multicenter study
verfasst von
Zenya Ito
Shiro Imagama
Tokumi Kanemura
Yudo Hachiya
Yasushi Miura
Mitsuhiro Kamiya
Yasutsugu Yukawa
Yoshihito Sakai
Yoshito Katayama
Norimitsu Wakao
Yukihiro Matsuyama
Naoki Ishiguro
Publikationsdatum
01.05.2013
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe 5/2013
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-012-2593-4

Weitere Artikel der Ausgabe 5/2013

European Spine Journal 5/2013 Zur Ausgabe

Arthropedia

Grundlagenwissen der Arthroskopie und Gelenkchirurgie. Erweitert durch Fallbeispiele, Videos und Abbildungen. 
» Jetzt entdecken

Notfall-TEP der Hüfte ist auch bei 90-Jährigen machbar

26.04.2024 Hüft-TEP Nachrichten

Ob bei einer Notfalloperation nach Schenkelhalsfraktur eine Hemiarthroplastik oder eine totale Endoprothese (TEP) eingebaut wird, sollte nicht allein vom Alter der Patientinnen und Patienten abhängen. Auch über 90-Jährige können von der TEP profitieren.

Arthroskopie kann Knieprothese nicht hinauszögern

25.04.2024 Gonarthrose Nachrichten

Ein arthroskopischer Eingriff bei Kniearthrose macht im Hinblick darauf, ob und wann ein Gelenkersatz fällig wird, offenbar keinen Unterschied.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Ärztliche Empathie hilft gegen Rückenschmerzen

23.04.2024 Leitsymptom Rückenschmerzen Nachrichten

Personen mit chronischen Rückenschmerzen, die von einfühlsamen Ärzten und Ärztinnen betreut werden, berichten über weniger Beschwerden und eine bessere Lebensqualität.

Update Orthopädie und Unfallchirurgie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.