Erschienen in:
09.06.2021 | Review Article
Can we predict mediastinal lymph nodes metastasis in esophagogastric junction cancer? Results of a systematic review and meta-analysis
verfasst von:
Mohamed Maatouk, Yacine Ben Safta, Ghassen Hamdi Kbir, Aymen Mabrouk, Anis Ben Dhaou, Sami Daldoul, Sofien Sayari, Karim Haouet, Mounir Ben Moussa
Erschienen in:
General Thoracic and Cardiovascular Surgery
|
Ausgabe 8/2021
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Abstract
Purpose
The aim of this systematic review and meta-analysis was to define clinical indicator that predicts mediastinal lymph nodes metastasis (MLNM) in patients with Esophagogastric junction cancer (EGJC) to select patient population requiring esophagectomy.
Methods
A systematic and electronic search of several electronic databases was performed up to August 2020. Studies containing information on risk factors for MLNM in patients diagnosed with EJGC and who underwent curative surgery were included.
Results
Two predictors, including undifferentiated type (OR = 1.82, 95% CI = 1.07–3.10, p = 0.03) and esophageal invasion length (EIL) (OR = 10.95, 95% CI = 6.37–18.82, p < 0.00001) were identified as significant predictors for the risk of MLNM.
Conclusion
Knowledge of the associations of these clinicopathological features with MLNM can be useful in determining operative strategy for EGJC.