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Zeitschrift

Cancer and Metastasis Reviews

Cancer and Metastasis Reviews OnlineFirst articles

16.08.2018

Preface

15.08.2018

Bioactive lipid metabolism in platelet “first responder” and cancer biology

Platelets can serve as “first responders” in cancer and metastasis. This is partly due to bioactive lipid metabolism that drives both platelet and cancer biology. The two primary eicosanoid metabolites that maintain platelet rapid response …

10.08.2018

Evaluation of oncogenic cysteinyl leukotriene receptor 2 as a therapeutic target for uveal melanoma

Uveal melanoma is a rare, but deadly, form of eye cancer that arises from melanocytes within the uveal tract. Although advances have emerged in treatment of the primary tumour, patients are still faced with vision loss, eye enucleation and lethal …

10.08.2018

The roles of the COX2/PGE2/EP axis in therapeutic resistance

Therapeutic resistance has been and remains to be the major challenge in developing successful treatments for different cancers and therefore, understanding the underlying mechanisms in the development of therapeutic resistance is crucial in …

10.08.2018

Triumph and tumult of matrix metalloproteinases and their crosstalk with eicosanoids in cancer

Cancer development and metastasis are associated to perturbation in metabolic functions of tumor cells and surrounding inflammatory and stromal cell responses. Eicosanoids and lipid mediators, in this regard, attract potential attention during …

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Über diese Zeitschrift

The transformation of biology from a descriptive, phenomenological discipline to one in which the regulatory principles are understood and predictably manipulated brings new opportunities to the study of cancer and the search for effective therapeutic modalities. Cancer and Metastasis Reviews offers a forum for critical review and discussion of these challenges.
Each issue presents five to seven different contributions on a single theme or topic, with an introductory essay from a distinguished individual in the field. Special emphasis is placed on subjects of relevance to the molecular and cellular biology of cancer metastasis and tumor progression, as well as to the treatment of metastatic disease. Occasional issues will be devoted to an in-depth clinical and biological analysis of a particular type of cancer.
The journal also reviews important recent developments in the biology and treatment of malignant disease, and highlights promising new directions.

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