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Cancer Chemotherapy and Pharmacology

Ausgabe 1/2008

Inhalt (22 Artikel)

Original Article

A phase II study of irinotecan and docetaxel combination chemotherapy for patients with previously treated metastatic or recurrent advanced gastric cancer

Sun Jin Sym, Heung Moon Chang, Hye Jin Kang, Sung Sook Lee, Min-Hee Ryu, Jae-Lyun Lee, Tae-Won Kim, Jeong Hwan Yook, Sung Tae Oh, Byung Sik Kim, Yoon-Koo Kang

Original Article

Effectiveness of pharmacokinetic modulating chemotherapy combined with cisplatin as induction chemotherapy in resectable locally advanced head and neck cancer: phase II study

Peter Mu-Hsin Chang, Po-Min Chen, Pen-Yuan Chu, Ling-Wei Wang, Shyh-Kuan Tai, Tung-Lung Tsai, Jui-Lin Huang, Yi-Fen Wang, Shyue-Yih Chang, Muh-Hwa Yang

Original Article

Resveratrol analog trans 3,4,5,4′-tetramethoxystilbene (DMU-212) mediates anti-tumor effects via mechanism different from that of resveratrol

Zengshuan Ma, Ommoleila Molavi, Azita Haddadi, Raymond Lai, Robert A. Gossage, Afsaneh Lavasanifar

Original Article

Does saturable formation of gemcitabine triphosphate occur in patients?

Lai-San Tham, Ling-Zhi Wang, Ross A. Soo, How-Sung Lee, Soo-Chin Lee, Boon-Cher Goh, Nicholas H. G. Holford

Original Article

A phase I pharmacological and biological study of PI-88 and docetaxel in patients with advanced malignancies

Laura Q. M. Chow, Daniel L. Gustafson, Cindy L. O’Bryant, Lia Gore, Michele Basche, Scott N. Holden, Mark C. Morrow, Stacy Grolnic, Brian R. Creese, Kaye L. Roberts, Kat Davis, Russell Addison, S. Gail Eckhardt

Original Article

Population pharmacokinetics of aprepitant and dexamethasone in the prevention of chemotherapy-induced nausea and vomiting

Susumu Nakade, Tomoya Ohno, Junsaku Kitagawa, Yoshitaka Hashimoto, Masahiro Katayama, Hiroshi Awata, Yasuo Kodama, Yasuyuki Miyata

Original Article

High intratumoral dihydropyrimidine dehydrogenase mRNA levels in pancreatic cancer associated with a high rate of response to S-1

Hidekazu Kuramochi, Kazuhiko Hayashi, Kazumi Uchida, Go Nakajima, Takashi Hatori, Kathleen D. Danenberg, Peter V. Danenberg, Masakazu Yamamoto

Original Article

Gastrointestinal dysmotility in 5-fluorouracil-induced intestinal mucositis outlasts inflammatory process resolution

Pedro M. G. Soares, José Maurício S. C. Mota, Antoniella S. Gomes, Ricardo B. Oliveira, Ana Maria S. Assreuy, Gerly Anne C. Brito, Armênio A. Santos, Ronaldo A. Ribeiro, Marcellus H. L. P. Souza

Original Article

A phase I and pharmacologic study of the combination of bortezomib and pegylated liposomal doxorubicin in patients with refractory solid tumors

E. Claire Dees, Bert H. O’Neil, Celeste M. Lindley, Frances Collichio, Lisa A. Carey, Jason Collins, William J. Riordan, Anastasia Ivanova, Dixie Esseltine, Robert Z. Orlowski

Original Article

A phase I pharmacodynamic trial of bortezomib in combination with doxorubicin in patients with advanced cancer

Noelle K. LoConte, James P. Thomas, Dona Alberti, Jennifer Heideman, Kimberly Binger, Rebecca Marnocha, Kyle Utecht, Peter Geiger, Jens Eickhoff, George Wilding, Jill Kolesar

Original Article

Antitumor activity of noscapine in human non-small cell lung cancer xenograft model

Tanise Jackson, Mahavir B. Chougule, Nkechi Ichite, Ram R. Patlolla, Mandip Singh

Original Article

In vitro evaluation of dichloro-bis(pyrazole)palladium(II) and dichloro-bis(pyrazole)platinum(II) complexes as anticancer agents

Frankline K. Keter, Stonard Kanyanda, Sylvester S. L. Lyantagaye, James Darkwa, D. Jasper G. Rees, Mervin Meyer

Original Article

Epidermal growth factor receptor serum (sEGFR) level may predict response in patients with EGFR positive advanced colorectal cancer treated with gefitinib?

M. G. Zampino, E. Magni, L. Santoro, L. Zorzino, P. Dell’Orto, A. Sonzogni, N. Fazio, L. Monfardini, A. Chiappa, R. Biffi, F. de Braud

Original Article

Gemcitabine at fixed dose-rate in patients with advanced soft tissue sarcomas: a mono-institutional phase II study

Virginia Ferraresi, Mariangela Ciccarese, Maria Cecilia Cercato, Carmen Nuzzo, Massimo Zeuli, Franco Di Filippo, Diana Giannarelli, Francesco Cognetti

Open Access Original Article

Preclinical discovery of ixabepilone, a highly active antineoplastic agent

Francis Y. F. Lee, Robert Borzilleri, Craig R. Fairchild, Amrita Kamath, Richard Smykla, Robert Kramer, Gregory Vite

Clinical Trial Report

A phase I study of gemcitabine plus palliative radiation therapy for advanced lung cancer

Brian Choi, H. Ian Robins, Joan Schiller, Minesh Mehta

Clinical Trial Report

Phase I trial of weekly trabectedin (ET-743) and gemcitabine in patients with advanced solid tumors

Wells A. Messersmith, Antonio Jimeno, David Ettinger, Dan Laheru, Julie Brahmer, Dina Lansey, Yasmin Khan, Ross C. Donehower, Yusri Elsayed, Peter Zannikos, Manuel Hidalgo

Letter to the Editor

Response to taxanes in triple negative breast cancer

Nilufer Bulut, Sadettin Kilickap, Ebru Sari, Kadri Altundag

Adjuvante Immuntherapie verlängert Leben bei RCC

25.04.2024 Nierenkarzinom Nachrichten

Nun gibt es auch Resultate zum Gesamtüberleben: Eine adjuvante Pembrolizumab-Therapie konnte in einer Phase-3-Studie das Leben von Menschen mit Nierenzellkarzinom deutlich verlängern. Die Sterberate war im Vergleich zu Placebo um 38% geringer.

Alectinib verbessert krankheitsfreies Überleben bei ALK-positivem NSCLC

25.04.2024 NSCLC Nachrichten

Das Risiko für Rezidiv oder Tod von Patienten und Patientinnen mit reseziertem ALK-positivem NSCLC ist unter einer adjuvanten Therapie mit dem Tyrosinkinase-Inhibitor Alectinib signifikant geringer als unter platinbasierter Chemotherapie.

Bei Senioren mit Prostatakarzinom auf Anämie achten!

24.04.2024 DGIM 2024 Nachrichten

Patienten, die zur Behandlung ihres Prostatakarzinoms eine Androgendeprivationstherapie erhalten, entwickeln nicht selten eine Anämie. Wer ältere Patienten internistisch mitbetreut, sollte auf diese Nebenwirkung achten.

ICI-Therapie in der Schwangerschaft wird gut toleriert

Müssen sich Schwangere einer Krebstherapie unterziehen, rufen Immuncheckpointinhibitoren offenbar nicht mehr unerwünschte Wirkungen hervor als andere Mittel gegen Krebs.

Update Onkologie

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