Ausgabe 3/2011
Inhalt (30 Artikel)
The role of Tau protein in resistance to paclitaxel
Marta Smoter, Lubomir Bodnar, Renata Duchnowska, Rafał Stec, Bartłomiej Grala, Cezary Szczylik
Involvement of RhoA and RalB in geranylgeranyltransferase I inhibitor-mediated inhibition of proliferation and migration of human oral squamous cell carcinoma cells
Masakazu Hamada, Tetsuei Miki, Soichi Iwai, Hidetaka Shimizu, Yoshiaki Yura
Enhancing cytotoxic agent activity in experimental pancreatic cancer through EMAP II combination therapy
Niranjan Awasthi, Margaret A. Schwarz, Roderich E. Schwarz
Induction of fetal hemoglobin and ABCB1 gene expression in 9-β-D-arabinofuranosylguanine-resistant MOLT-4 cells
Anna Fyrberg, Curt Peterson, Bertil Kågedal, Kourosh Lotfi
Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats
Izet M. Kapetanovic, Miguel Muzzio, Zhihua Huang, Thomas N. Thompson, David L. McCormick
Modulatory effects of curcumin on multi-drug resistance-associated protein 5 in pancreatic cancer cells
Yan Li, Jezrael L. Revalde, Glen Reid, James W Paxton
Phase II study of sequential treatment with S-1 and cisplatin for metastatic gastric cancer
Eishi Baba, Taito Esaki, Hiroshi Ariyama, Kenji Mitsugi, Tatsuma Morikita, Hiromitsu Fujishima, Hitoshi Kusaba, Shuji Nakano, Koichi Akashi
Cytochrome P450 ω-hydroxylase promotes angiogenesis and metastasis by upregulation of VEGF and MMP-9 in non-small cell lung cancer
Wei Yu, Li Chen, Yu-Qing Yang, John R. Falck, Austin M. Guo, Ying Li, Jing Yang
A two-part Phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics
Claire L. Mitchell, J. P. B. O’Connor, C. Roberts, Y. Watson, A. Jackson, S. Cheung, J. Evans, J. Spicer, A. Harris, C. Kelly, S. Rudman, M. Middleton, A. Fielding, J. Tessier, H. Young, G. J. M. Parker, G. C. Jayson
A phase I study of imatinib mesylate in combination with chlorambucil in previously treated chronic lymphocytic leukemia patients
Jonathan Hebb, Sarit Assouline, Caroline Rousseau, Pierre DesJardins, Stephen Caplan, Merrill J. Egorin, Lilian Amrein, Raquel Aloyz, Lawrence Panasci
Pharmacokinetics of aprepitant and dexamethasone after administration of chemotherapeutic agents and effects of plasma substance P concentration on chemotherapy-induced nausea and vomiting in Japanese cancer patients
Toshiaki Takahashi, Yukiko Nakamura, Asuka Tsuya, Haruyasu Murakami, Masahiro Endo, Nobuyuki Yamamoto
Primary tumor and patient characteristics in breast cancer as predictors of adjuvant therapy regimen: a regression model
Valerie Francescutti, Forough Farrokhyar, Richard Tozer, Barbara Heller, Peter Lovrics, Graham Jansz, Kamyar Kahnamoui
Over-expression of MDR1 in amrubicinol-resistant lung cancer cells
Osamu Takakuwa, Tetsuya Oguri, Hiroaki Ozasa, Takehiro Uemura, Daishi Kasai, Mikinori Miyazaki, Ken Maeno, Shigeki Sato
Prospective multicenter study to investigate the introduction rate of second-line S-1 in gemcitabine-refractory unresectable pancreatic cancer
Hiroki Kawashima, Akihiro Itoh, Eizaburo Ohno, Masanao Nakamura, Ryoji Miyahara, Naoki Ohmiya, Kazuo Hara, Akira Kanamori, Terutomo Itoh, Tomoyuki Taki, Takanori Hirai, Senju Hashimoto, Kinichi Takeda, Hidemi Goto, Yoshiki Hirooka
Effects of endurance training on combined goserelin acetate and doxorubicin treatment–induced cardiac dysfunction
David S. Hydock, Traci L. Parry, Brock T. Jensen, Chia-Ying Lien, Carole M. Schneider, Reid Hayward
Evaluation of a non cystatin-C-based novel algorithm to calculate individual glomerular filtration rate in cancer patients receiving carboplatin
Karin Holweger, Hans-Peter Lipp, Jos H. Beijnen, Carsten Bokemeyer, Joerg Thomas Hartmann
Sunitinib in combination with paclitaxel plus carboplatin in patients with advanced solid tumors: phase I study results
Elisabeth I. Heath, George R. Blumenschein Jr, Roger B. Cohen, Patricia M. LoRusso, Noelle K. LoConte, Sindy T. Kim, Ana Ruiz-Garcia, Richard C. Chao, George Wilding
Role of platelet-activating factor in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice
Pedro M. G. Soares, Roberto C. P. Lima-Junior, José Maurício S. C. Mota, Priscilla F. C. Justino, Gerly Anne C. Brito, Ronaldo A. Ribeiro, Fernando Q. Cunha, Marcellus H. L. P. Souza
Effect of radiation on the penetration of irinotecan in rat cerebrospinal fluid
Amit Khatri, M. Waleed Gaber, Richard C. Brundage, Michael D. Naimark, Suzan K. Hanna, Clinton F. Stewart, Mark N. Kirstein
Phase 1 study of conatumumab, a pro-apoptotic death receptor 5 agonist antibody, in Japanese patients with advanced solid tumors
T. Doi, H. Murakami, A. Ohtsu, N. Fuse, T. Yoshino, N. Yamamoto, N. Boku, Y. Onozawa, C-P. Hsu, K. S. Gorski, G. Friberg, T. Kawaguchi, T. Sasaki
Thymidylate synthase and thymidine phosphorylase as predictive markers of capecitabine monotherapy in patients with anthracycline- and taxane-pretreated metastatic breast cancer
Su Jin Lee, Yoon La Choi, Yeon Hee Park, Seung Tae Kim, Eun Yoon Cho, Jin Seok Ahn, Young-Hyuck Im
Potential candidate biomarkers for heterogeneity in triple-negative breast cancer (TNBC)
Eun Yoon Cho, Myung Hee Chang, Yoon La Choi, Jeong Eon Lee, Seok Jin Nam, Jung-Hyun Yang, Yeon Hee Park, Jin Seok Ahn, Young-Hyuck Im
Circulating endothelial cells predict for response to bevacizumab-based chemotherapy in metastatic colorectal cancer
Satoshi Matsusaka, Mitsukuni Suenaga, Yuji Mishima, Koichi Takagi, Yasuhito Terui, Nobuyuki Mizunuma, Kiyohiko Hatake
Weekly paclitaxel in patients with recurrent or metastatic head and neck cancer
M. Tahara, H. Minami, Y. Hasegawa, K. Tomita, A. Watanabe, K. Nibu, M. Fujii, Y. Onozawa, Y. Kurono, D. Sagae, T. Seriu, M. Tsukuda
Pharmacokinetics, pharmacodynamics and metabolism of the dimeric pyrrolobenzodiazepine SJG-136 in rats
Joel M. Reid, Sarah A. Buhrow, Mary J. Kuffel, Lee Jia, Victoria J. Spanswick, John A. Hartley, David E. Thurston, Joseph E. Tomaszewski, Matthew M. Ames
Preoperative radiotherapy with capecitabine and mitomycin C in locally advanced rectal carcinoma
Suzana Stojanovic, Ivan Popov, Ljiljana Radosevic-Jelic, Marjan Micev, Nenad Borojevic, Vladimir Nikolic, Zoran Krivokapic, Dragutin Kecmanovic, Dusica Gavrilovic, Iva Kezic
The slow cell death response when screening chemotherapeutic agents
Joseph Blois, Adam Smith, Lee Josephson
Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor
Paul Hamberg, Margaret M. Woo, Lin-Chi Chen, Jaap Verweij, Maria Grazia Porro, Lily Zhao, Wenkui Li, Diane van der Biessen, Sunil Sharma, Thomas Hengelage, Maja de Jonge
Methylseleninic acid inhibits HDAC activity in diffuse large B-cell lymphoma cell lines
Shireen Kassam, Heidi Goenaga-Infante, Lenushka Maharaj, Crispin T. Hiley, Simone Juliger, Simon P. Joel
5-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases
Pierre-Yves Cordier, André Nau, Joseph Ciccolini, Manuela Oliver, Cédric Mercier, Bruno Lacarelle, Eric Peytel