Ausgabe 6/2009
Inhalt (25 Artikel)
Dual targeting of EGFR and HER-2 in colon cancer cell lines
Efstathia Giannopoulou, Anna Antonacopoulou, Konstantina Floratou, Athanasios G. Papavassiliou, Haralabos P. Kalofonos
Lack of toxicity of a STAT3 decoy oligonucleotide
Malabika Sen, Patricia J. Tosca, Christa Zwayer, Michael J. Ryan, Jerry D. Johnson, Katherine A. B. Knostman, Patricia C. Giclas, James O. Peggins, Joseph E. Tomaszewski, Timothy P. McMurray, Changyou Li, Michael S. Leibowitz, Robert L. Ferris, William E. Gooding, Sufi M. Thomas, Daniel E. Johnson, Jennifer R. Grandis
Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression
Hongli Liu, Shu-Ling Liang, Sheetal Kumar, Crystal M. Weyman, Wendy Liu, Aimin Zhou
Studies of structure–activity relationship on plant polyphenol-induced suppression of human liver cancer cells
Jacky Loa, Pierce Chow, Kai Zhang
Successful re-challenge with panitumumab in patients who developed hypersensitivity reactions to cetuximab: report of three cases and review of literature
Muhammad Wasif Saif, J. Peccerillo, Von Potter
Growth inhibitory activity of a novel lectin from Cliona varians against K562 human erythroleukemia cells
Alexandre F. S. Queiroz, Rodrigo A. Silva, Raniere M. Moura, Juliana L. Dreyfuss, Edgar J. Paredes-Gamero, Ana C. S. Souza, Ivarne L. S. Tersariol, Elizeu A. Santos, Helena B. Nader, Giselle Z. Justo, Maurício P. de Sales
Multiple-pool cell lifespan models for neutropenia to assess the population pharmacodynamics of unbound paclitaxel from two formulations in cancer patients
Jürgen B. Bulitta, Ping Zhao, Robert D. Arnold, Dean R. Kessler, Richard Daifuku, James Pratt, Gabriel Luciano, Axel-R. Hanauske, Hans Gelderblom, Ahmad Awada, William J. Jusko
Mechanistic population pharmacokinetics of total and unbound paclitaxel for a new nanodroplet formulation versus Taxol in cancer patients
Jürgen B. Bulitta, Ping Zhao, Robert D. Arnold, Dean R. Kessler, Richard Daifuku, James Pratt, Gabriel Luciano, Axel-R Hanauske, Hans Gelderblom, Ahmad Awada, William J. Jusko
Phase I study of cetuximab, erlotinib, and bevacizumab in patients with advanced solid tumors
Chia-Chi Lin, Emiliano Calvo, Kyriakos P. Papadopoulos, Amita Patnaik, John Sarantopoulos, Alain C. Mita, Glenn G. Preston, Monica M. Mita, Jordi Rodon, Theresa Mays, I-Tien Yeh, Pat O’Rourke, Chris H. Takimoto, Janet E. Dancey, Helen Chen, Anthony W. Tolcher
Phase I and pharmacokinetic study of mitomycin C and celecoxib as potential modulators of tumor resistance to irinotecan in patients with solid malignancies
Y. Xu, J. M. Kolesar, L. J. Schaaf, R. Drengler, W. Duan, G. Otterson, C. Shapiro, J. Kuhn, M. A. Villalona-Calero
A multi-center phase II study of S-1 plus paclitaxel as first-line therapy for patients with advanced or recurrent unresectable gastric cancer
Jae Jin Lee, Si-Young Kim, Hyun-Cheol Chung, Kyung-Hee Lee, Hong-Suk Song, Won-Ki Kang, Young-Seon Hong, In-Sil Choi, Young Yeul Lee, In-Sook Woo, Jin-Hyuk Choi
Cisplatin and weekly docetaxel with concurrent thoracic radiotherapy for locally advanced stage III non-small-cell lung cancer
Masaru Nakamura, Tomonobu Koizumi, Munehara Hayasaka, Masanori Yasuo, Kenji Tsushima, Keishi Kubo, Kotaro Gomi, Naoto Shikama
Experiences and practical conclusions concerning temsirolimus use and adverse event management in advanced renal cell carcinoma within a compassionate use program in Germany
Holger Gerullis, Lothar Bergmann, Luise Maute, Christoph Eimer, Thomas Otto
Role of BCRP as a biomarker for predicting resistance to 5-fluorouracil in breast cancer
Jianhui Yuan, Hui Lv, Bo Peng, Chengkun Wang, Yanhui Yu, Zhimin He
Multi-center phase II trial of chemo-radiotherapy with 5-fluorouracil, leucovorin and oxaliplatin in locally advanced esophageal cancer
Vanna Chiarion-Sileni, Roberto Innocente, Raffaele Cavina, Alberto Ruol, Luigi Corti, Jacopo Pigozzo, Paola Del Bianco, Uberto Fumagalli, Armando Santoro, Ermanno Ancona
Diverse cross-resistance phenotype to ET-743 and PM00104 in multi-drug resistant cell lines
Zhenfeng Duan, Edwin Choy, Jose Maria Jimeno, Carmen Del Maria Cuevas, Henry J. Mankin, Francis J. Hornicek
Cytotoxic diarylheptanoid induces cell cycle arrest and apoptosis via increasing ATF3 and stabilizing p53 in SH-SY5Y cells
Ze Tian, Ning An, Bin Zhou, Peigen Xiao, Isaac S. Kohane, Erxi Wu
Irinotecan monotherapy as second-line treatment in advanced pancreatic cancer
Seong Yoon Yi, Young Suk Park, Hyo Song Kim, Hyun Jung Jun, Kyoung Ha Kim, Myung Hee Chang, Min Jae Park, Ji Eun Uhm, Jeeyun Lee, Se Hoon Park, Joon Oh Park, Jong Kyun Lee, Kyu Taek Lee, Ho Yeong Lim, Won Ki Kang
A phase I study of Triapine® in combination with doxorubicin in patients with advanced solid tumors
William R. Schelman, Sherry Morgan-Meadows, Rebecca Marnocha, Fred Lee, Jens Eickhoff, Wei Huang, Marcia Pomplun, Zhisheng Jiang, Dona Alberti, Jill M. Kolesar, Percy Ivy, George Wilding, Anne M. Traynor
Extended survival of a HER-2-positive metastatic breast cancer patient with brain metastases also treated with intrathecal trastuzumab
Mariantonietta Colozza, Elisa Minenza, Stefania Gori, Daniela Fenocchio, Cristina Paolucci, Cynthia Aristei, Piero Floridi
Isolated molecular relapse in FIP1L1-PDGFRα hypereosinophilic syndrome after discontinuation and single weekly dose of imatinib: need of quantitative molecular procedures to modulate imatinib dose
Massimo Breccia, Daniela Cilloni, Laura Cannella, Caterina Stefanizzi, Agostino Tafuri, Angelo Fama, Michelina Santopietro, Giuseppe Saglio, Giuliana Alimena
Life-threatening toxicities in a patient with UGT1A1*6/*28 and SLCO1B1*15/*15 genotypes after irinotecan-based chemotherapy
Hiroshi Takane, Katsuyuki Kawamoto, Tomohiro Sasaki, Kuniaki Moriki, Kazuyo Moriki, Hiroya Kitano, Shun Higuchi, Kenji Otsubo, Ichiro Ieiri
Lenalidomide: in vitro evaluation of the metabolism and assessment of cytochrome P450 inhibition and induction
Gondi Kumar, Henry Lau, Oscar Laskin
Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile
Cedric Mercier, Charlotte Dupuis, Aurore Blesius, Raphaelle Fanciullino, Chen Guang Yang, Laetitia Padovani, Sarah Giacometti, Nicolas Frances, Athanassios Iliadis, Florence Duffaud, Joseph Ciccolini
5-FU pretreatment potentiates cisplatin-induced apoptosis through up-regulation of thrombospondin-1 in head and neck squamous cell carcinomas
Bei Xu, Peng Liu