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Current Bladder Dysfunction Reports

Erschienen in:

31.05.2021 | Reconstructed Bladder Function & Dysfunction (M Kaufman, Section Editor)

Cannabinoid Therapy in Female Pelvic Medicine and Reconstructive Surgery: Current Evidence and Future Directions

verfasst von: Jocelyn Stairs, Finlay Maguire, Christian Lehmann, Ashley Cox

Erschienen in: Current Bladder Dysfunction Reports | Ausgabe 3/2021

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Abstract

Purpose of Review

In this review, we examine the current literature regarding the use of cannabinoids in several areas of female pelvic medicine and reconstructive surgery (FPMRS) including overactive bladder, interstitial cystitis/bladder pain syndrome, and chronic pelvic pain.

Recent Findings

Animal models support the role of the endocannabinoid system in the pathophysiology of these disorders and several drug targets have been identified. However, clinical studies remain limited. Palmitoylethanolamine (PEA) is emerging as a possible therapy for pain in this context.

Summary

There is currently insufficient evidence to support cannabinoid therapy in disorders related to FPMRS and many of the clinical studies to date have limitations in terms of size and study design.

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Titel: Cannabinoid Therapy in Female Pelvic Medicine and Reconstructive Surgery: Current Evidence and Future Directions
verfasst von: Jocelyn Stairs
Finlay Maguire
Christian Lehmann
Ashley Cox
Publikationsdatum: 31.05.2021
Verlag: Springer US
Erschienen in: Current Bladder Dysfunction Reports / Ausgabe 3/2021
Print ISSN: 1931-7212
Elektronische ISSN: 1931-7220
DOI: https://doi.org/10.1007/s11884-021-00632-5

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