Background
Methods
Study population
Computed tomography
Echocardiography
Grade | Papillary muscle calcium | Mitral annular calcium | Aortic valve sclerosis | Aorta root calcium |
---|---|---|---|---|
0
| Absent | Absent | Absent | Absent |
1
| Present | Mild < 5 mm | Mild | Present |
2
| Moderate 5–10 mm | Moderate | ||
3
| Severe > 10 mm | Severe |
Statistical analysis
Results
Clinical characteristics, eCS and CCTA data in the entire study population
Entire population (n = 141) | CAD > 50% (n = 55) | No CAD > 50% (n = 86) | p | |
---|---|---|---|---|
Age, median (IQR) | 67 (58–75) | 71 (61–80) | 65 (55–73) | <0.01 |
Male gender (%) | 80 (57%) | 31 (56%) | 49 (57%) | ns |
Hypertension (%) | 93 (66%) | 46 (84%) | 47 (55%) | <0.01 |
Family history of CAD (%) | 47 (33%) | 22 | 25 | ns |
Smoking (%) | 43 (30%) | 17 | 26 | ns |
Hypercolesterolemia (%) | 77 (55%) | 32 | 45 | ns |
Diabetes (%) | 20 (14%) | 11 | 9 | ns |
Obesity (%) | 12 (8%) | 4 | 8 | ns |
n. of vessels CAD > 50% (0-1-2-3) | 86-32-13-11 | - | - | - |
eCS > 1 | 35 (25%) | 22 (40%) | 13 (15%) | <0.01 |
eCS, median, IQR, (range) | 1, 0–1, (0–6) | 1, 1–2, (0–6) | 1, 0–1, (0–5) | 0.015 |
CACS, median, IQR, (range) | 29, 0–294, (0–3316) | 294, 47–618, (0–3316) | 3, 0–46, (0–1109) | < 0.001 |
nCACS, median, IQR, (range) | 0, 0–97, (0–4377) | 54, 0–178, (0–4377) | 0, 0–65, (0–2936) | < 0.01 |
Reproducibility of eCS
Correlation data
Correlation, rho, p value | nCACS | CACS | Number of vessels > 50% | Number of vessels > 70% |
---|---|---|---|---|
eCS | 0.64, p < 0.0001 | 0.43, p < 0.0001 | ns | 0.28, p < 0.05 |
nCACS | - | - | ns | ns |
CACS | 0.51, p < 0.0001 | - | 0.44, p < 0.001 | 0.29, p < 0.05 |