Introduction
PROMISE
PROMISE | SCOT-HEART | CAPP | Min et al. | |
---|---|---|---|---|
Recruiting centres | 193 | 12 | 1 | 1 |
Study groups | CCTA vs functional testing (ETT, stress echo or radionucleotide perfusion imaging) | CCTA and standard care vs standard care alone | CCTA vs ETT | CCTA vs MPS |
Primary endpoint | Composite of all-cause mortality, myocardial infarction, hospitalisation for unstable angina, and major complications of cardiovascular procedures or diagnostic testing | Proportion of patients diagnosed with angina pectoris secondary to coronary heart disease at 6 weeks | Difference in symptoms from baseline to 3 months | Angina-specific health status |
Follow-up duration (months) | 25 | 20 | 12 | 55 days |
PROMISE | SCOT-HEART | CAPP | Min et al. | ||
---|---|---|---|---|---|
Number | 10,003 | 4146 | 448 | 180 | |
Age (years) | 61 | 57 | 59 | 56, 59 | |
Female (%) | 53 | 44 | 45 | 44 | |
Pre-test probability (%) | 53 | 47 | 45, 48 | – | |
Chest pain (%) | Typical angina | 12 | 35 | 34 | 32 |
Atypical angina | 78 | 24 | 8 | 23 | |
Non-anginal chest pain | 11 | 41 | 67 | 27 |