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International Journal of Public Health

Erschienen in:

01.09.2015 | Original Article

Cardiovascular disease among people with drug use disorders

verfasst von: Birgitte Thylstrup, Thomas Clausen, Morten Hesse

Erschienen in: International Journal of Public Health | Ausgabe 6/2015

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Abstract

Objectives

To present the prevalence and incidence of cardiovascular disease (CVD) in a national cohort of patients seeking treatment for drug use disorders (DUD).

Methods

This is a longitudinal record linkage study of consecutive DUD treatment admissions between 2000 and 2006 from Denmark.

Results

Of 17,642 patients seeking treatment for DUD, 828 individuals (4.53 %) had a history of CVD at treatment entry. Among the remaining patients, 16,820 were traced and 1535 new incident cases of CVD were observed during a mean follow-up time of 7.5 years. The incidence of CVD was associated with intravenous drug use [subhazard ratio (SHR) = 1.41, p < 0.001], not responding to injection question (SHR = 1.23, p = 0.005), older age (SHR = 1.04 per year, p = 0.000), use of prescription methadone (SHR = 1.32, p < 0.001), use of benzodiazepines (SHR = 1.21, p = 0.005), and being referred to methadone treatment (SHR = 1.15, p = 0.022). The use of amphetamines was negatively associated with the risk of CVD within this cohort (SHR = 0.75, p = 0.001).

Conclusions

Patients injecting drugs using prescribed methadone were at elevated risk for cardiovascular disease and should be monitored for CVD. Opioid medications should be evaluated in terms of their cardiovascular sequelae.

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Titel: Cardiovascular disease among people with drug use disorders
verfasst von: Birgitte Thylstrup
Thomas Clausen
Morten Hesse
Publikationsdatum: 01.09.2015
Verlag: Springer Basel
Erschienen in: International Journal of Public Health / Ausgabe 6/2015
Print ISSN: 1661-8556
Elektronische ISSN: 1661-8564
DOI: https://doi.org/10.1007/s00038-015-0698-3

Springer Medizin

Abstract

Objectives

Methods

Results

Conclusions

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