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Erschienen in: Pediatric Cardiology 3/2004

01.06.2004

Cardiovascular Embryology

verfasst von: R. Abdulla, G. A. Blew, M. J. Holterman

Erschienen in: Pediatric Cardiology | Ausgabe 3/2004

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Abstract

During the first 20 days of development, the human embryo has no cardiovascular structure. Over the next month, the heart and great vessels complete their development and look very much like they will at full gestation. This amazing process transforms isolated angiogenic cell islets into a complex, four-chambered structure. During this transformation, the single heart tube begins to beat at 23 days of development and by 30 days blood circulates through the embryo.
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Literatur
2.
Zurück zum Zitat Anderson, RH 1986Description of ventricular septal defect—or how long is a piece of string?Int J Cardiol13267278CrossRefPubMed Anderson, RH 1986Description of ventricular septal defect—or how long is a piece of string?Int J Cardiol13267278CrossRefPubMed
3.
Zurück zum Zitat Anderson, RH 1991Simplifying the understanding of congenital malformation of the heart.Int J Cardiol32131142CrossRefPubMed Anderson, RH 1991Simplifying the understanding of congenital malformation of the heart.Int J Cardiol32131142CrossRefPubMed
4.
Zurück zum Zitat Anderson, RH, Wilkinson, JL, Rosenquist, GC, Bergsma, D 1978The bulbus cordis.Morphogenesis and Malformation of the Cardiovascular System.LissNew York128 Anderson, RH, Wilkinson, JL, Rosenquist, GC, Bergsma, D 1978The bulbus cordis.Morphogenesis and Malformation of the Cardiovascular System.LissNew York128
5.
Zurück zum Zitat Anderson, PAW 1995The molecular genetics of cardiovascular disease.Curr Opin Cardiol103343PubMed Anderson, PAW 1995The molecular genetics of cardiovascular disease.Curr Opin Cardiol103343PubMed
6.
Zurück zum Zitat Bartelings, MM 1989The outflow tract of the heart—embryologic and morphologic correlations.Int J Cardiol22289300CrossRefPubMed Bartelings, MM 1989The outflow tract of the heart—embryologic and morphologic correlations.Int J Cardiol22289300CrossRefPubMed
7.
Zurück zum Zitat Bartelings, MM 1990The Outflow Tract of the Heart - embryologic and morphholayre correlations. Fnt. J Condcol22289300 Bartelings, MM 1990The Outflow Tract of the Heart - embryologic and morphholayre correlations. Fnt. J Condcol22289300
8.
Zurück zum Zitat Bartelings, MM, Gittenberger-deGroot, AC 1988The arterial orifice level in the early human embryo.Anat Embryol177537542PubMed Bartelings, MM, Gittenberger-deGroot, AC 1988The arterial orifice level in the early human embryo.Anat Embryol177537542PubMed
9.
Zurück zum Zitat Bartelings, MM, et al. 1986Contribution of the aortopulmonary septum to the muscular outlet septum in the human heart.Acta Morphol Neerl-Scand24181192PubMed Bartelings, MM,  et al. 1986Contribution of the aortopulmonary septum to the muscular outlet septum in the human heart.Acta Morphol Neerl-Scand24181192PubMed
10.
Zurück zum Zitat Becker, AE, Anderson, RH 1984Cardiac embryology.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York339358 Becker, AE, Anderson, RH 1984Cardiac embryology.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York339358
11.
Zurück zum Zitat Benson, DW, et al. 1996New understanding in the genetics of congenital heart disease.Curr Opin Pediatr8505511PubMed Benson, DW,  et al. 1996New understanding in the genetics of congenital heart disease.Curr Opin Pediatr8505511PubMed
12.
Zurück zum Zitat Bockman, ED 1987Effect of neural crest on the development of the heart and arch arteries in the chick.Am J Anat180332341PubMed Bockman, ED 1987Effect of neural crest on the development of the heart and arch arteries in the chick.Am J Anat180332341PubMed
13.
Zurück zum Zitat Bolender, D, Holterman, ML 2001Animated thoughts on teaching human development.FASEB J15Abstract 793.1 Bolender, D, Holterman, ML 2001Animated thoughts on teaching human development.FASEB J15Abstract 793.1
14.
Zurück zum Zitat Burn, J, Goodship, J 1996Developmental genetics of the heart.Curr Opin Genet Dev6322326CrossRefPubMed Burn, J, Goodship, J 1996Developmental genetics of the heart.Curr Opin Genet Dev6322326CrossRefPubMed
15.
Zurück zum Zitat Clark, EB 1984Hemodynamic control of the chick embryo cardiovascular system.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York337386 Clark, EB 1984Hemodynamic control of the chick embryo cardiovascular system.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York337386
16.
Zurück zum Zitat Colvin, EV 1998Cardiac embryology.Garson, A Jr eds. The Science and Practice of Pediatric Cardiology, 2nd edn.Williams & WilkinsBaltimore91126 Colvin, EV 1998Cardiac embryology.Garson, A Jr eds. The Science and Practice of Pediatric Cardiology, 2nd edn.Williams & WilkinsBaltimore91126
17.
Zurück zum Zitat Creazzo, TL, et al. 1998Role of cardiac neural crest in cardiovascular development.Ann Rev Physiol60267286CrossRef Creazzo, TL,  et al. 1998Role of cardiac neural crest in cardiovascular development.Ann Rev Physiol60267286CrossRef
18.
Zurück zum Zitat Hay, DA 1978Development and fusion of the endocardial cushion.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York6990 Hay, DA 1978Development and fusion of the endocardial cushion.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York6990
19.
Zurück zum Zitat Holterman MJ, et al (1999) The Visible Embryo Project: new approaches to embryology education [abstract]. American Academy of Pediatrics Surgical section meeting, Washington DC Holterman MJ, et al (1999) The Visible Embryo Project: new approaches to embryology education [abstract]. American Academy of Pediatrics Surgical section meeting, Washington DC
20.
Zurück zum Zitat Holterman MJ, Blew G, Bolender D, Abdulla R (2001) Clinical education development using multimedia [abstract]. Biannual meeting of the American Association of Clinical Anatomists and the British Association of Clinical Anatomists, Cambridge, UK Holterman MJ, Blew G, Bolender D, Abdulla R (2001) Clinical education development using multimedia [abstract]. Biannual meeting of the American Association of Clinical Anatomists and the British Association of Clinical Anatomists, Cambridge, UK
21.
Zurück zum Zitat Holterman, MJ, Oladapo, A, Abdulla, R 1999Clinically relevant embryology: new approach to education [abstract].American Academy of PediatricsWashington, DC Holterman, MJ, Oladapo, A, Abdulla, R 1999Clinically relevant embryology: new approach to education [abstract].American Academy of PediatricsWashington, DC
22.
Zurück zum Zitat Kathiriya, IS, Srivastava, D 2000Left–right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease.Am J Med Genet97271279CrossRefPubMed Kathiriya, IS, Srivastava, D 2000Left–right asymmetry and cardiac looping: implications for cardiac development and congenital heart disease.Am J Med Genet97271279CrossRefPubMed
23.
Zurück zum Zitat Kirby, ML 1989Plasticity and predetermination of mesencephalic and trunk neural crest transplanted into the region of the cardiac neural crest.Dev Biol134402412PubMed Kirby, ML 1989Plasticity and predetermination of mesencephalic and trunk neural crest transplanted into the region of the cardiac neural crest.Dev Biol134402412PubMed
24.
Zurück zum Zitat Kirby, ML, Waldo, KL 1990Role of neural crest in congenital heart disease.Circulation82232340 Kirby, ML, Waldo, KL 1990Role of neural crest in congenital heart disease.Circulation82232340
25.
Zurück zum Zitat Larsen, WJ 1997aHuman Embryology, 2nd edn.Churchill LivingstoneNew York4961 Larsen, WJ 1997aHuman Embryology, 2nd edn.Churchill LivingstoneNew York4961
26.
Zurück zum Zitat Larsen, WJ 1997bHuman Embryology, 2nd edn.Churchill LivingstoneNew York151188 Larsen, WJ 1997bHuman Embryology, 2nd edn.Churchill LivingstoneNew York151188
27.
Zurück zum Zitat Los, JA 1978Cardiac septation and development of the aorta, pulmonary trunk, and pulmonary veins.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York109138 Los, JA 1978Cardiac septation and development of the aorta, pulmonary trunk, and pulmonary veins.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York109138
28.
Zurück zum Zitat McBride, RE 1981Development of the outflow tract and closure of the interventricular septum.Am J Anat106309331 McBride, RE 1981Development of the outflow tract and closure of the interventricular septum.Am J Anat106309331
29.
Zurück zum Zitat McGowan Jr, FX 1992Cardiovascular and airway interactions.Int Anesthesiol Clin302144PubMed McGowan Jr, FX 1992Cardiovascular and airway interactions.Int Anesthesiol Clin302144PubMed
30.
Zurück zum Zitat Moorman, AF, de Jong, F, Denyn, MM, et al. 1998Development of the cardiac conduction system.Circ Res82629644PubMed Moorman, AF, de Jong, F, Denyn, MM,  et al. 1998Development of the cardiac conduction system.Circ Res82629644PubMed
31.
Zurück zum Zitat Morse, DE 1978Scanning electron microscopy of the developing septa in the chick heart.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York91107 Morse, DE 1978Scanning electron microscopy of the developing septa in the chick heart.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformations of the Cardiovascular System.LissNew York91107
32.
Zurück zum Zitat Nadal-Ginard, B, Mahdavi, V 1993Basic mechanism of cardiac gene expression.Eur Heart J14211 Nadal-Ginard, B, Mahdavi, V 1993Basic mechanism of cardiac gene expression.Eur Heart J14211
33.
Zurück zum Zitat Nora, J, Berg, K, Nora, AH 1991Cardiovascular Disease: Genetics, Epidemiology and Prevention.Oxford University PressNew York Nora, J, Berg, K, Nora, AH 1991Cardiovascular Disease: Genetics, Epidemiology and Prevention.Oxford University PressNew York
34.
Zurück zum Zitat Olson, EN, Srivastava, D 1996Molecular pathways controlling heart development.Science272671675PubMed Olson, EN, Srivastava, D 1996Molecular pathways controlling heart development.Science272671675PubMed
35.
Zurück zum Zitat Pensky, B 1982Review of Medical Embryology.McMillanNew York291355 Pensky, B 1982Review of Medical Embryology.McMillanNew York291355
36.
Zurück zum Zitat Pexieder, T 1978Development of the outflow tract of the embryonic heart.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformation of the Cardiovascular System.LissNew York2968 Pexieder, T 1978Development of the outflow tract of the embryonic heart.Rosenquist, GCBergsma, D eds. Morphogenesis and Malformation of the Cardiovascular System.LissNew York2968
37.
Zurück zum Zitat Pexieder, T, Janecek, P 1984Organogenesis of the human embryonic and early fetal heart as studied by microdissection and SEM.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York401422 Pexieder, T, Janecek, P 1984Organogenesis of the human embryonic and early fetal heart as studied by microdissection and SEM.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York401422
38.
Zurück zum Zitat Srivastava, D 2001Genetic assembly of the heart: implications for congenital heart disease.Annu Rev Physiol63451469CrossRefPubMed Srivastava, D 2001Genetic assembly of the heart: implications for congenital heart disease.Annu Rev Physiol63451469CrossRefPubMed
39.
Zurück zum Zitat Steding, G, Seidl, W 1984Cardiac septation in normal development.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York481500 Steding, G, Seidl, W 1984Cardiac septation in normal development.Nora, JJTalao, A eds. Congenital Heart Disease: Causes and Processes.FuturaNew York481500
40.
Zurück zum Zitat Thompson, RP 1985Morphogenesis of human cardiac outflow.Anat Rec213578586PubMed Thompson, RP 1985Morphogenesis of human cardiac outflow.Anat Rec213578586PubMed
41.
Zurück zum Zitat Van Mierop, LHS 1979Morphological development of the heart.Berne, RM eds. Handbook of Physiology, the Cardiovascular System.American Physiology SocietyBethesda, MD128 Van Mierop, LHS 1979Morphological development of the heart.Berne, RM eds. Handbook of Physiology, the Cardiovascular System.American Physiology SocietyBethesda, MD128
42.
Zurück zum Zitat Van Mierop, LHS 1986Cardiovascular anomalies in DiGeorge syndrome and importance of neural crest as a possible pathogenetic factor.Am J Cardiol58133137CrossRefPubMed Van Mierop, LHS 1986Cardiovascular anomalies in DiGeorge syndrome and importance of neural crest as a possible pathogenetic factor.Am J Cardiol58133137CrossRefPubMed
44.
Zurück zum Zitat Wenink, ACG, Gittenberger-deGroot, AC 1985The role of atrioventricular endocardial cushion in the septation of the heart.Int J Cardiol82544CrossRefPubMed Wenink, ACG, Gittenberger-deGroot, AC 1985The role of atrioventricular endocardial cushion in the septation of the heart.Int J Cardiol82544CrossRefPubMed
45.
Zurück zum Zitat Whiten, S, Smart, SD, McLachlan, JC, Aiton, JF 1998Computer-aided interactive three-dimensional reconstruction of the embryonic human heart.J Anat193337345CrossRefPubMed Whiten, S, Smart, SD, McLachlan, JC, Aiton, JF 1998Computer-aided interactive three-dimensional reconstruction of the embryonic human heart.J Anat193337345CrossRefPubMed
Metadaten
Titel
Cardiovascular Embryology
verfasst von
R. Abdulla
G. A. Blew
M. J. Holterman
Publikationsdatum
01.06.2004
Erschienen in
Pediatric Cardiology / Ausgabe 3/2004
Print ISSN: 0172-0643
Elektronische ISSN: 1432-1971
DOI
https://doi.org/10.1007/s00246-003-0585-1

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