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Journal of Clinical Psychology in Medical Settings

Erschienen in:

01.03.2010

Changes in Pediatric Health-Related Quality of Life in Cystic Fibrosis After IV Antibiotic Treatment for Pulmonary Exacerbations

verfasst von: Avani C. Modi, Crystal S. Lim, Kimberly A. Driscoll, Carrie Piazza-Waggoner, Alexandra L. Quittner, Jamie Wooldridge

Erschienen in: Journal of Clinical Psychology in Medical Settings | Ausgabe 1/2010

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Abstract

Intravenous (IV) antibiotic therapy for pulmonary exacerbations (PE) has been shown to improve pulmonary functioning for patients with cystic fibrosis (CF); however, little is known about its effects on pediatric health-related quality of life (HRQOL). This prospective study assessed the impact of IV treatment of a PE on generic and CF-specific HRQOL for children and adolescents with CF. Participants included 52 children and adolescents with CF experiencing a PE (M _age = 13.6 years; 54% males; \( M_{{{\text{FEV}}_{1\% } }} \) predicted = 58.8%). HRQOL, pulmonary functioning, and body mass index were assessed before and after IV antibiotic treatment. Results of this prospective, observational study indicated significant improvements on CFQ-R Respiratory (M _{change score} = 11.7; 95% CI = 6.3–17.1; p < .0001) and Weight (M _{change score} = 15.9; 95% CI = 7.9–23.8; p < .0001) scales. The CF-specific measure was more sensitive to changes in HRQOL than the generic instrument. These data suggest that CF-specific HRQOL improves with treatment for a PE with IV antibiotics. The noted statistically and clinically significant changes in the CFQ-respiratory scale indicate that the measure may be beneficial to pulmonary health care teams.

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Titel: Changes in Pediatric Health-Related Quality of Life in Cystic Fibrosis After IV Antibiotic Treatment for Pulmonary Exacerbations
verfasst von: Avani C. Modi
Crystal S. Lim
Kimberly A. Driscoll
Carrie Piazza-Waggoner
Alexandra L. Quittner
Jamie Wooldridge
Publikationsdatum: 01.03.2010
Verlag: Springer US
Erschienen in: Journal of Clinical Psychology in Medical Settings / Ausgabe 1/2010
Print ISSN: 1068-9583
Elektronische ISSN: 1573-3572
DOI: https://doi.org/10.1007/s10880-009-9179-2

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