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World Journal of Surgery

Erschienen in:

09.05.2019 | Scientific Review

Chronic Postoperative Opioid Use: A Systematic Review

verfasst von: Ashley Hinther, Omar Abdel-Rahman, Winson Y. Cheung, May Lynn Quan, Joseph C. Dort

Erschienen in: World Journal of Surgery | Ausgabe 9/2019

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Abstract

Background

There are a number of studies in the literature that describe the prevalence, causes, and factors associated with chronic postoperative opioid use, but there is a lack of synthesis of the literature to guide clinicians in optimally managing postoperative pain while avoiding opioid dependence. Thus, the goal of this study was to perform a systematic review of the literature to investigate the prevalence of chronic postoperative opioid use and the associated risk factors.

Materials and methods

A systematic search was performed using Ovid Medline and Embase according to PRISMA guidelines. Data were collected on the following outcomes of interest: prevalence of opioid use at 3, 6, and 12 months postoperatively, and risk factors associated with chronic postoperative opioid use.

Results

Forty-three articles were included in the final analysis. The mean prevalence of chronic postoperative opioid use in all populations at 3, 6, and 12 months postoperatively was 30.5%, 25.6%, and 25.2%, respectively. The prevalence of patients who developed chronic opioid use at 3, 6, and 12 months postoperatively was 10.4%, 8.5%, and 9.8%, respectively. Forty of the articles analyzed risk factors associated with chronic postoperative opioid use. The most common associated risk factor identified was preoperative opioid use with 27 articles demonstrating a significant association with chronic postoperative opioid use.

Discussion

The current opioid crisis is in part secondary to the prevalence of chronic opioid use following surgery. This study identified associated risk factors with chronic postoperative opioid use, which may help identify patients at risk for developing chronic postoperative opioid use.

Manchikanti L, Helm S, Fellows B et al (2012) Opioid epidemic in the United States. Pain Physician 15:ES9–38PubMed

Rudd RA, Aleshire N, Zibbell JE, Gladden RM (2016) Increases in drug and opioid overdose deaths—United States, 2000–2014. Am J Transpl 16:1323–1327. https://doi.org/10.1111/ajt.13776 CrossRef

Giraudon I, Lowitz K, Dargan PI et al (2013) Prescription opioid abuse in the UK. Br J Clin Pharmacol 76:823–824. https://doi.org/10.1111/bcp.12133 CrossRefPubMedPubMedCentral

Pain Society Quality of Care Committee (1995) Quality improvement guidelines for the treatment of acute pain and cancer pain. American Pain Society Quality of Care Committee. J Am Med Assoc 274:1874–1880. https://doi.org/10.1001/jama.274.23.1874 CrossRef

American Society of Anesthesiologists Task Force on Pain Management (1995) Practice guidelines for acute pain management in the perioperative setting. A report by the American Society of Anesthesiologists Task Force on Pain Management. Acute Pain Section. Anesthesiology 82:1071–1081

Lin DH, Lucas E, Murimi IB et al (2017) Financial conflicts of interest and the centers for disease control and prevention's 2016 guideline for prescribing opioids for chronic pain. JAMA Intern Med 177:427–428. https://doi.org/10.1001/jamainternmed.2016.8471 CrossRefPubMed

Pizzo PA, Clark NM (2012) Alleviating suffering 101—pain relief in the United States. N Engl J Med 366:197–199. https://doi.org/10.1056/NEJMp1109084 CrossRefPubMed

Lanser P, Gesell S (2001) Pain management: the fifth vital sign. Healthc Benchmarks 8:68–70PubMed

Dowell D, Haegerich TM, Chou R (2016) CDC guideline for prescribing opioids for chronic pain—United States, 2016. JAMA 315:1624–1645. https://doi.org/10.1001/jama.2016.1464 CrossRefPubMedPubMedCentral

10.

Porter J, Jick H (1980) Addiction rare in patients treated with narcotics. N Engl J Med 302:123PubMed

11.

Portenoy RK, Foley KM (1986) Chronic use of opioid analgesics in non-malignant pain: report of 38 cases. Pain 25:171–186CrossRefPubMed

12.

Volkow ND, McLellan TA, Cotto JH et al (2011) Characteristics of opioid prescriptions in 2009. JAMA 305:1299–1301. https://doi.org/10.1001/jama.2011.401 CrossRefPubMedPubMedCentral

13.

Menendez ME, Ring D, Bateman BT (2015) Preoperative opioid misuse is associated with increased morbidity and mortality after elective orthopaedic surgery. Clin Orthop Relat Res 473:2402–2412. https://doi.org/10.1007/s11999-015-4173-5 CrossRefPubMedPubMedCentral

14.

Levy B, Paulozzi L, Mack KA, Jones CM (2015) Trends in opioid analgesic-prescribing rates by specialty, U.S., 2007–2012. Am J Prev Med 49:409–413. https://doi.org/10.1016/j.amepre.2015.02.020 CrossRefPubMedPubMedCentral

15.

Inacio MC, Pratt NL, Roughead EE et al (2016) Opioid use after total hip arthroplasty surgery is associated with revision surgery. BMC Musculoskelet Disord 17:122. https://doi.org/10.1186/s12891-016-0970-6 CrossRefPubMedPubMedCentral

16.

Inacio MC, Hansen C, Pratt NL et al (2016) Risk factors for persistent and new chronic opioid use in patients undergoing total hip arthroplasty: a retrospective cohort study. BMJ Open 6:e010664. https://doi.org/10.1136/bmjopen-2015-010664 CrossRefPubMedPubMedCentral

17.

Clarke H, Soneji N, Ko DT et al (2014) Rates and risk factors for prolonged opioid use after major surgery: population based cohort study. BMJ 348:g1251. https://doi.org/10.1136/bmj.g1251 CrossRefPubMedPubMedCentral

18.

Alam A, Gomes T, Zheng H et al (2012) Long-term analgesic use after low-risk surgery: a retrospective cohort study. Arch Intern Med 172:425–430. https://doi.org/10.1001/archinternmed.2011.1827 CrossRefPubMed

19.

Centers for Disease Control and Pre (2016) Guideline for prescribing opioids for chronic pain. J Pain Palliat Care Pharmacother 30:138–140. https://doi.org/10.3109/15360288.2016.1173761 CrossRef

20.

McCarthy M (2015) Opioids should be last resort to treat chronic pain, says draft CDC guideline. BMJ 351:h6905. https://doi.org/10.1136/bmj.h6905 CrossRefPubMed

21.

Canada H Opioid Wisely. In: httpschoosingwiselycanada.orgcampaignopioid-wisely. Accessed 5 Jan 2019

22.

Raebel MA, Newcomer SR, Bayliss EA et al (2014) Chronic opioid use emerging after bariatric surgery. Pharmacoepidemiol Drug Saf 23:1247–1257. https://doi.org/10.1002/pds.3625 CrossRefPubMed

23.

Baldini A, Korff Von M, Lin EHB (2012) A review of potential adverse effects of long-term opioid therapy: a practitioner’s guide. Prim Care Companion CNS Disord. https://doi.org/10.4088/PCC.11m01326

24.

White AG, Birnbaum HG, Mareva MN et al (2015) Direct costs of opioid abuse in an insured population in the United States. J Manag Care Pharm 11:469–479. https://doi.org/10.18553/jmcp.2005.11.6.469 CrossRef

25.

Wells G (2004) The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analysis. https://www.ohri.ca/programs/clinical_epidemiology.oxford.htm

26.

Lee MM, Pain MSS (2011) A comprehensive review of opioid-induced hyperalgesia. researchgate.net

27.

Armaghani SJ, Lee DS, Bible JE et al (2014) Preoperative opioid use and its association with perioperative opioid demand and postoperative opioid independence in patients undergoing spine surgery. Spine 39:E1524–E1530. https://doi.org/10.1097/BRS.0000000000000622 CrossRefPubMed

28.

Carroll I, Barelka P, Wang CK et al (2012) A pilot cohort study of the determinants of longitudinal opioid use after surgery. Anesth Analg 115:694–702. https://doi.org/10.1213/ANE.0b013e31825c049f CrossRefPubMed

29.

Mudumbai SC, Oliva EM, Lewis ET et al (2016) Time-to-cessation of postoperative opioids: a population-level analysis of the veterans affairs health care system. Pain Med 17:1732–1743. https://doi.org/10.1093/pm/pnw015 CrossRefPubMed

30.

Brummett CM, Waljee JF, Goesling J et al (2017) New persistent opioid use after minor and major surgical procedures in US adults. JAMA Surg 152:e170504. https://doi.org/10.1001/jamasurg.2017.0504 CrossRefPubMedPubMedCentral

31.

Capdevila X, Barthelet Y, Biboulet P et al (1999) Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery. Anesthesiology 91:8–15CrossRefPubMed

32.

Halawi MJ, Grant SA, Bolognesi MP (2015) Multimodal analgesia for total joint arthroplasty. Orthopedics 38:e616–e625. https://doi.org/10.3928/01477447-20150701-61 CrossRefPubMed

33.

Wick EC, Grant MC, Wu CL (2017) Postoperative multimodal analgesia pain management with nonopioid analgesics and techniques: a review. JAMA Surg 152:691–697. https://doi.org/10.1001/jamasurg.2017.0898 CrossRefPubMed

34.

Hartford LB, Van Koughnett JAM, Murphy PB et al (2019) Standardization of outpatient procedure (STOP) narcotics: a prospective non-inferiority study to reduce opioid use in outpatient general surgical procedures. J Am Coll Surg 228:81–88.e1. https://doi.org/10.1016/j.jamcollsurg.2018.09.008 CrossRefPubMed

35.

Cook CE, Rhon DI, Lewis BD, George SZ (2017) Post-operative opioid pain management patterns for patients who receive hip surgery. Subst Abuse Treat Prev Policy 12:14. https://doi.org/10.1186/s13011-017-0094-5 CrossRefPubMedPubMedCentral

36.

Ahn J, Bohl DD, Elboghdady I et al (2015) Postoperative narcotic consumption in workman's compensation patients following a minimally invasive transforaminal lumbar interbody fusion. Spine 40:1284–1288. https://doi.org/10.1097/BRS.0000000000000994 CrossRefPubMed

37.

Dabbagh Al Z, Jansson KA, Stiller CO et al (2016) Long-term pattern of opioid prescriptions after femoral shaft fractures. Acta Anaesthesiol Scand 60:634–641. https://doi.org/10.1111/aas.12666 CrossRef

38.

Anderson JT, Haas AR, Percy R et al (2015) Chronic opioid therapy after lumbar fusion surgery for degenerative disc disease in a workers' compensation setting. Spine 40:1775–1784. https://doi.org/10.1097/BRS.0000000000001054 CrossRefPubMed

39.

Anthony CA, Westermann RW, Bedard N et al (2017) Opioid demand before and after anterior cruciate ligament reconstruction. Am J Sports Med 45:3098–3103. https://doi.org/10.1177/0363546517719226 CrossRefPubMed

40.

Bateman BT, Franklin JM, Bykov K et al (2016) Persistent opioid use following cesarean delivery: patterns and predictors among opioid-naive women. Am J Obstet Gynecol 215:353.e1–353.e18. https://doi.org/10.1016/j.ajog.2016.03.016 CrossRef

41.

Bedard NA, DeMik DE, Dowdle SB, Callaghan JJ (2018) Trends and risk factors for prolonged opioid use after unicompartmental knee arthroplasty. Bone Joint J 100-B:62–67. https://doi.org/10.1302/0301-620X.100B1.BJJ-2017-0547.R1

42.

Bedard NA, Pugely AJ, Westermann RW et al (2017) Opioid use after total knee arthroplasty: trends and risk factors for prolonged use. J Arthroplasty 32:2390–2394. https://doi.org/10.1016/j.arth.2017.03.014 CrossRefPubMed

43.

Brat GA, Agniel D, Beam A et al (2018) Postsurgical prescriptions for opioid naive patients and association with overdose and misuse: retrospective cohort study. BMJ 360:j5790. https://doi.org/10.1136/bmj.j5790 CrossRefPubMedPubMedCentral

44.

Connolly J, Javed Z, Raji MA et al (2017) Predictors of long-term opioid use following lumbar fusion surgery. Spine 42:1405–1411. https://doi.org/10.1097/BRS.0000000000002133 CrossRefPubMedPubMedCentral

45.

Deyo RA, Hallvik SE, Hildebran C, et al (2018) Use of prescription opioids before and after an operation for chronic pain (lumbar fusion surgery). Pain. https://doi.org/10.1097/j.pain.0000000000001202

46.

Goesling J, Moser SE, Zaidi B et al (2016) Trends and predictors of opioid use after total knee and total hip arthroplasty. Pain 157:1259–1265. https://doi.org/10.1097/j.pain.0000000000000516 CrossRefPubMedPubMedCentral

47.

Hansen CA, Inacio MCS, Pratt NL et al (2017) Chronic use of opioids before and after total knee arthroplasty: a retrospective cohort study. J Arthroplasty 32:811–817.e1. https://doi.org/10.1016/j.arth.2016.09.040 CrossRefPubMed

48.

Hernandez NM, Parry JA, Taunton MJ (2017) Patients at risk: large opioid prescriptions after total knee arthroplasty. J Arthroplasty 32:2395–2398. https://doi.org/10.1016/j.arth.2017.02.060 CrossRefPubMed

49.

Holman JE, Stoddard GJ, Higgins TF (2013) Rates of prescription opiate use before and after injury in patients with orthopaedic trauma and the risk factors for prolonged opiate use. J Bone Joint Surg Am 95:1075–1080. https://doi.org/10.2106/JBJS.L.00619 CrossRefPubMed

50.

Huang A, Azam A, Segal S et al (2016) Chronic postsurgical pain and persistent opioid use following surgery: the need for a transitional pain service. Pain Manag 6:435–443. https://doi.org/10.2217/pmt-2016-0004 CrossRefPubMed

51.

Johnson SP, Chung KC, Zhong L et al (2016) Risk of prolonged opioid use among opioid-naive patients following common hand surgery procedures. J Hand Surg 41:947–957.e3. https://doi.org/10.1016/j.jhsa.2016.07.113 CrossRef

52.

Kim N, Matzon JL, Abboudi J et al (2016) A prospective evaluation of opioid utilization after upper-extremity surgical procedures: identifying consumption patterns and determining prescribing guidelines. J Bone Joint Surg Am 98:e89CrossRefPubMed

53.

Kulshrestha S, Barrantes F, Samaniego M, Luan FL (2014) Chronic opioid analgesic usage post-kidney transplantation and clinical outcomes. Clin Transpl 28:1041–1046. https://doi.org/10.1111/ctr.12414 CrossRef

54.

Mahowald ML, Singh JA, Majeski P (2005) Opioid use by patients in an orthopedics spine clinic. Arthritis Rheum 52:312–321. https://doi.org/10.1002/art.20784 CrossRefPubMed

55.

Marcusa DP, Mann RA, Cron DC et al (2017) Prescription opioid use among opioid-naive women undergoing immediate breast reconstruction. Plast Reconstr Surg 140:1081–1090. https://doi.org/10.1097/PRS.0000000000003832 CrossRefPubMed

56.

Massey GM, Dodds HN, Roberts CS et al (2005) Toxicology screening in orthopedic trauma patients predicting duration of prescription opioid use. J Addict Dis 24:31–41CrossRefPubMed

57.

Namba RS, Singh A, Paxton EW, Inacio MCS (2018) Patient factors associated with prolonged postoperative opioid use after total knee arthroplasty. J Arthroplasty 33:2449–2454. https://doi.org/10.1016/j.arth.2018.03.068 CrossRefPubMed

58.

Pang J, Tringale KR, Tapia VJ et al (2017) Chronic opioid use following surgery for oral cavity cancer. JAMA Otolaryngol Head Neck Surg 143:1187–1194. https://doi.org/10.1001/jamaoto.2017.0582 CrossRefPubMedPubMedCentral

59.

Politzer CS, Kildow BJ, Goltz DE et al (2018) Trends in opioid utilization before and after total knee arthroplasty. J Arthroplasty 33:S147–S153.e1. https://doi.org/10.1016/j.arth.2017.10.060

60.

Raebel MA, Newcomer SR, Reifler LM et al (2013) Chronic use of opioid medications before and after bariatric surgery. JAMA 310:1369–1376. https://doi.org/10.1001/jama.2013.278344 CrossRefPubMed

61.

Rosenbloom BN, McCartney CJL, Canzian S et al (2017) Predictors of prescription opioid use 4 months after traumatic musculoskeletal injury and corrective surgery: a prospective study. J Pain 18:956–963. https://doi.org/10.1016/j.jpain.2017.03.006 CrossRefPubMed

62.

Rozet I, Nishio I, Robbertze R et al (2014) Prolonged opioid use after knee arthroscopy in military veterans. Anesth Analg 119:454–459. https://doi.org/10.1213/ANE.0000000000000292 CrossRefPubMed

63.

Schoenfeld AJ, Nwosu K, Jiang W et al (2017) Risk factors for prolonged opioid use following spine surgery, and the association with surgical intensity, among opioid-naive patients. J Bone Joint Surg Am 99:1247–1252. https://doi.org/10.2106/JBJS.16.01075 CrossRefPubMed

64.

Soneji N, Clarke HA, Ko DT, Wijeysundera DN (2016) Risks of developing persistent opioid use after major surgery. JAMA Surg 151:1083–1084. https://doi.org/10.1001/jamasurg.2016.1681 CrossRefPubMed

65.

Stark N, Kerr S, Stevens J (2017) Prevalence and predictors of persistent post-surgical opioid use: a prospective observational cohort study. Anaesth Intensive Care 45:700–706CrossRefPubMed

66.

Sun EC, Bateman BT, Memtsoudis SG et al (2017) Lack of association between the use of nerve blockade and the risk of postoperative chronic opioid use among patients undergoing total knee arthroplasty: evidence from the Marketscan database. Anesth Analg 125:999–1007. https://doi.org/10.1213/ANE.0000000000001943 CrossRefPubMed

67.

Sun EC, Darnall BD, Baker LC, Mackey S (2016) Incidence of and risk factors for chronic opioid use among opioid-naive patients in the postoperative period. JAMA Intern Med 176:1286–1293. https://doi.org/10.1001/jamainternmed.2016.3298 CrossRefPubMedPubMedCentral

68.

Westermann RW, Anthony CA, Bedard N et al (2017) Opioid consumption after rotator cuff repair. Arthroscopy 33:1467–1472. https://doi.org/10.1016/j.arthro.2017.03.016 CrossRefPubMed

69.

Zarling BJ, Yokhana SS, Herzog DT, Markel DC (2016) Preoperative and postoperative opiate use by the arthroplasty patient. J Arthroplasty 31:2081–2084. https://doi.org/10.1016/j.arth.2016.03.061 CrossRefPubMed

Titel: Chronic Postoperative Opioid Use: A Systematic Review
verfasst von: Ashley Hinther
Omar Abdel-Rahman
Winson Y. Cheung
May Lynn Quan
Joseph C. Dort
Publikationsdatum: 09.05.2019
Verlag: Springer International Publishing
Erschienen in: World Journal of Surgery / Ausgabe 9/2019
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323
DOI: https://doi.org/10.1007/s00268-019-05016-9

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Abstract

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Materials and methods

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Discussion

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