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Clinical and Translational Oncology

Clinical and Translational Oncology OnlineFirst articles

17.05.2019 | Brief Research Article

Feasibility of a deep hyperthermia and radiotherapy programme for advanced tumors: first Spanish experience

Hyperthermia (HT) is used to increase the tumor’s temperature up to 39–43 °C to sensitize cells to the effects of radiation/chemotherapy. Biological effects of HT include changes in perfusion and oxygenation as well as inhibition of DNA repair …

15.05.2019 | Research Article

Effectiveness of fentanyl pectin nasal citrate in controlling episodes of breakthrough cancer pain triggered by routine radiotherapy procedures

Pain is one of the most frequent distressing symptom associated to cancer, particularly in patients with advanced disease when the prevalence is up to 80% [ 1 – 3 ]. In this group of patients, management of pain remains a particular challenge [ 4 …

15.05.2019 | Research Article

Synergistic anti-tumor effect of paclitaxel and miR-34a combined with ultrasound microbubbles on cervical cancer in vivo and in vitro

According to the recent National Comprehensive Cancer Network (NCCN) guidelines, cervical cancer is the second leading cause of female genital tract cancer-related mortality worldwide, causing approximately 266,000 deaths each year [ 1 ]. The …

10.05.2019 | Correspondence

Is it time to change follow-up recommendations in colorectal cancer?

10.05.2019 | Research Article

Coping strategies and depressive symptoms in cancer patients

Cancer is known to negatively affect patients’ psychological status. More than 16% suffer from depression [ 1 , 2 ] and this deteriorates their quality of life. Moreover, depression has been associated with lower survival rates [ 2 – 4 ]. Given the …

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Clinical and Translational Oncology is an international journal devoted to fostering interaction between experimental and clinical oncology. It covers all aspects of research on cancer, from the more basic discoveries dealing with both cell and molecular biology of tumour cells, to the most advanced clinical assays of conventional and new drugs. In addition, the journal has a strong commitment to facilitating the transfer of knowledge from the basic laboratory to the clinical practice, with the publication of educational series devoted to closing the gap between molecular and clinical oncologists. Molecular biology of tumours, identification of biomarkers for cancer diagnosis, prognosis or prediction of treatment response, identification of new targets for cancer therapy, as well as development of new technologies for research and treatment of cancer are the major themes covered by both the educational series and research articles. A broad spectrum of subjects, including the molecular and cellular bases of disease, aetiology, pathophysiology, pathology, epidemiology, clinical features, and the diagnosis, prognosis and treatment of cancer, will be considered for publication.

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