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International Journal of Clinical Oncology

Erschienen in:

01.12.2015 | Original Article

Clinical characteristics and outcome of pneumothorax after stereotactic body radiotherapy for lung tumors

verfasst von: Kaori Asai, Katsumasa Nakamura, Yoshiyuki Shioyama, Tomonari Sasaki, Yoshio Matsuo, Saiji Ohga, Tadamasa Yoshitake, Kotaro Terashima, Makoto Shinoto, Keiji Matsumoto, Hidenari Hirata, Hiroshi Honda

Erschienen in: International Journal of Clinical Oncology | Ausgabe 6/2015

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Abstract

Backgound

We retrospectively investigated the clinical characteristics and outcome of pneumothorax after stereotactic body radiotherapy (SBRT) for lung tumors.

Methods

Between April 2003 and July 2012, 473 patients with lung tumors were treated with SBRT. We identified 12 patients (2.5 %) with pneumothorax caused by SBRT, and evaluated the clinical features of pneumothorax.

Results

All of the tumors were primary lung cancers. The severity of radiation pneumonitis was grade 1 in 10 patients and grade 2 in two patients. Nine patients had emphysema. The planning target volume and pleura overlapped in 11 patients, and the tumors were attached to the pleura in 7 patients. Rib fractures were observed in three patients before or at the same time as the diagnosis of pneumothorax. The median time to onset of pneumothorax after SBRT was 18.5 months (4–84 months). The severity of pneumothorax was grade 1 in 11 patients and grade 3 in one patient.

Conclusion

Although pneumothorax was a relatively rare late adverse effect after SBRT, some patients demonstrated pneumothorax after SBRT for peripheral lung tumors. Although most pneumothorax was generally tolerable and self-limiting, careful follow-up is needed.

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Titel: Clinical characteristics and outcome of pneumothorax after stereotactic body radiotherapy for lung tumors
verfasst von: Kaori Asai
Katsumasa Nakamura
Yoshiyuki Shioyama
Tomonari Sasaki
Yoshio Matsuo
Saiji Ohga
Tadamasa Yoshitake
Kotaro Terashima
Makoto Shinoto
Keiji Matsumoto
Hidenari Hirata
Hiroshi Honda
Publikationsdatum: 01.12.2015
Verlag: Springer Japan
Erschienen in: International Journal of Clinical Oncology / Ausgabe 6/2015
Print ISSN: 1341-9625
Elektronische ISSN: 1437-7772
DOI: https://doi.org/10.1007/s10147-015-0833-4

Springer Medizin

Clinical characteristics and outcome of pneumothorax after stereotactic body radiotherapy for lung tumors