International Journal of Clinical Oncology

International Journal of Clinical Oncology OnlineFirst articles

20.06.2022 | Original Article

Survival benefit of using pemetrexed for EGFR mutation-positive advanced non-small-cell lung cancer in a randomized phase III study comparing gefitinib to cisplatin plus docetaxel (WJTOG3405)

Epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitors (TKIs) are the standard of care for the first-line treatment of advanced non-small-cell lung cancer (NSCLC) with sensitizing EGFR mutation [ 1 – 5 ]. However, no novel effective …

19.06.2022 | Original Article

Microsatellite instability in patients with hepato-biliary-pancreatic malignancies in clinical practice (KHBO 1903)

Recently, there has been remarkable progress in the development of pharmacotherapeutic cancer treatments such as immune checkpoint inhibitors (ICIs). ICIs include the anti-programmed cell death-1 (PD-1) antibody, anti-programmed cell death …

Open Access 18.06.2022 | Original Article

Prognostic significance of additional histologic features for subclassification of pathological T3 colon cancer

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17.06.2022 | Original Article

Characteristics and clinical outcomes of patients with advanced gastric or gastroesophageal cancer treated in and out of randomized clinical trials of first-line immune checkpoint inhibitors

Randomized clinical trials (RCTs) are best ways to establish new treatments. However, only a limited subset of patients may participate in these trials partially because of many defined inclusion and exclusion criteria [ 1 – 3 ]. While strict …

17.06.2022 | Original Article

Development of a national health policy logic model to accelerate the integration of oncology and palliative care: a nationwide Delphi survey in Japan

Cancer is the world’s leading cause of death, accounting for approximately 10.0 million deaths each year, and one in six deaths [ 1 ]. In addition, cancer is known to cause severe distress (e.g., physical, psychological and social) in patients and …