Clinical evaluation of TOF versus non-TOF on PET artifacts in simultaneous PET/MR: a dual centre experience
- 26.01.2017
- Original Article
Erschienen in:
- Verfasst von
- Edwin E. G. W. ter Voert
- Patrick Veit-Haibach
- Sangtae Ahn
- Florian Wiesinger
- M. Mehdi Khalighi
- Craig S. Levin
- Andrei H. Iagaru
- Greg Zaharchuk
- Martin Huellner
- Gaspar Delso
Abstract
Purpose
Our objective was to determine clinically the value of time-of-flight (TOF) information in reducing PET artifacts and improving PET image quality and accuracy in simultaneous TOF PET/MR scanning.
Methods
A total 65 patients who underwent a comparative scan in a simultaneous TOF PET/MR scanner were included. TOF and non-TOF PET images were reconstructed, clinically examined, compared and scored. PET imaging artifacts were categorized as large or small implant-related artifacts, as dental implant-related artifacts, and as implant-unrelated artifacts. Differences in image quality, especially those related to (implant) artifacts, were assessed using a scale ranging from 0 (no artifact) to 4 (severe artifact).
Results
A total of 87 image artifacts were found and evaluated. Four patients had large and eight patients small implant-related artifacts, 27 patients had dental implants/fillings, and 48 patients had implant-unrelated artifacts. The average score was 1.14 ± 0.82 for non-TOF PET images and 0.53 ± 0.66 for TOF images (p < 0.01) indicating that artifacts were less noticeable when TOF information was included.
Conclusion
Our study indicates that PET image artifacts are significantly mitigated with integration of TOF information in simultaneous PET/MR. The impact is predominantly seen in patients with significant artifacts due to metal implants.
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- Titel
- Clinical evaluation of TOF versus non-TOF on PET artifacts in simultaneous PET/MR: a dual centre experience
- Verfasst von
-
Edwin E. G. W. ter Voert
Patrick Veit-Haibach
Sangtae Ahn
Florian Wiesinger
M. Mehdi Khalighi
Craig S. Levin
Andrei H. Iagaru
Greg Zaharchuk
Martin Huellner
Gaspar Delso
- Publikationsdatum
- 26.01.2017
- Verlag
- Springer Berlin Heidelberg
- Erschienen in
-
European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 7/2017
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089 - DOI
- https://doi.org/10.1007/s00259-017-3619-2
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