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Zeitschrift

Clinical & Experimental Metastasis

Official Journal of the Metastasis Research Society

Clinical & Experimental Metastasis OnlineFirst articles

07.01.2019 | Research Paper

Sema4D expression and secretion are increased by HIF-1α and inhibit osteogenesis in bone metastases of lung cancer

Most lung cancer bone metastasis are characterized by osteolytic destruction and osteoblastic activity is significantly decreased, suggesting that hypoxia may play a critical role in the process, but the underlying mechanisms remain unknown.

13.12.2018 | Research Paper Open Access

Frequent discordance in PD-1 and PD-L1 expression between primary breast tumors and their matched distant metastases

Programmed death-1 (PD-1) is an immune checkpoint that is able to inhibit the immune system by binding to its ligand programmed death-ligand 1 (PD-L1). In many cancer types, among which breast cancer, prognostic and/or predictive values have been …

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Über diese Zeitschrift

Clinical & Experimental Metastasis is an international, multidisciplinary journal devoted to the rapid publication of fundamental advances in basic and applied metastasis research.
The coverage encompasses all aspects of metastasis research, whether laboratory-based, experimental or clinical and therapeutic. It includes such areas as molecular biology, pharmacology, tumour biology, and clinical cancer treatment (with all its subdivisions of surgery, chemotherapy and radio-therapy as well as pathology and epidemiology) insofar as these disciplines are concerned with the journal's core subject of metastasis formation, prevention and treatment.
Clinical & Experimental Metastasis is the official journal of the Metastasis Research Society.

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