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Erschienen in:
01.06.2007 | CME Questions
CME Questions
Erschienen in: Comprehensive Therapy | Ausgabe 2/2007
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1.
TRUE or FALSE. A diagnosis of Alzheimer’s disease can be confirmed by a brain MRI.
a.
True
b.
False
2.
Which of the following is true of Alzheimer’s disease?
a.
Increased CSF tau protein and increased CSF beta amyloid
b.
Increased CSF tau protein and decreased CSF beta amyloid
c.
Decreased CSF tau protein and increased CSF beta amyloid
d.
Decreased CSF tau protein and decreased CSF beta amyloid
3.
TRUE or FALSE. A form of Alzheimer’s disease involves a dominant disorder mediated through the apolipoprotein E allele.
a.
True
b.
False
4.
Which of the following is not among the typical potential side effects of the cholinesterase inhibitors?
a.
Increased gastric acid secretion
b.
Vivid dreams
c.
Insomnia
d.
Nausea
e.
Hypertension
5.
Which of the following is not an acetylcholinergic inhibitor?
a.
Galantamine
b.
Donepezil
c.
Memantine
d.
Rivastigmine
6.
Stevens–Johnson syndrome is a mucocutacous disease characterized by skin involvement in:
a.
<10%
b.
10–30%
c.
>30%
d.
50%
7.
Which of the following can cause conjunctival pigmentation?
a.
Epinephrine
b.
Silver
c.
Minocycline
d.
All of the above
8.
Acute phase ocular sequelae in Stevens–Johnson syndrome is characterized by:
a.
Corneal ulceration
b.
Tarsal ulceration
c.
Symblepharon
d.
Eyelid margin keratinization
9.
TRUE or FALSE. Topical ointment vehicles can deposit as vacuolated spaces within the conjunctival stroma.
a.
True
b.
False
10.
Whether deposited conjunctival pigment is of melanic origin or not is determined by:
a.
Gram stain
b.
PAS stain
c.
Calcofluor
d.
Potassium permanganate bleach
11.
TRUE or FALSE. Depression is less common in heart failure patients than in general population.
a.
True
b.
False
12.
TRUE or FALSE. Heart failure patients with depression are more likely to have increased mortality.
a.
True
b.
False
13.
TRUE or FALSE. The Center for Epidemiological Studies Depression (CES-D) tool is routinely used in clinical practice to screen patients with depression.
a.
True
b.
False
14.
TRUE or FALSE. A single-item question that directly asks about depression caused by heart failure will likely identify the most severe cases of depression in heart failure who are at risk of increased mortality.
a.
True
b.
False
15.
TRUE or FALSE. Barriers to effective diagnosis of depression in heart failure may include inadequate time during clinic visits and a single item question to screen patients may help busy clinicians identify those with increased risk of mortality.
a.
True
b.
False
16.
TRUE or FALSE. Alkaptonuria is inherited as an autosomal dominant condition
a.
True
b.
False
17.
TRUE or FALSE. The disease is due to deficiency of enzyme Homogentisic acid 1, 2 dioxygenase which is needed in the metabolism of amino acid phenylalanine
a.
True
b.
False
18.
TRUE or FALSE. Alkaptonuria does not cause discoloration or loosening of the cartilage
a.
True
b.
False
19.
TRUE or FALSE. The discoloration of the conjunctiva is due pigmentation of the vascular endothelium
a.
True
b.
False
20.
TRUE or FALSE. Dark urine is the earliest manifestation of the disease
a.
True
b.
False
21.
The most effective method in reducing the blinding complication of retinopathy of prematurity (ROP) is:
a.
To start vitamin E treatment very early after delivery.
b.
To meticulously monitor oxygen saturation in the arterial blood.
c.
To do timely screening and perform retinal laser ablation without delay when indicated.
d.
To meticulously monitor carbon dioxide level.
e.
To give antenatal steroids to the mother.
22.
The most common cause of bilateral blindness in children is
a.
Retinblastoma (RB).
b.
ROP
c.
Strabismus
d.
PHPV
e.
Coat’s disease
23.
The following diseases can present as leukocoria EXCEPT:
a.
ROP
b.
RB
c.
PHPV
d.
Coat’s disease
e.
High hyperopia
24.
The most important risk factor for developing aggressive ROP is:
a.
Presence of patent ductus arteriosus
b.
Very low birth weight
c.
Exposure to light at NICU
d.
Sepsis
e.
Multiple blood transfusions
25.
TRUE or FALSE. Vitamin E is thought to decrease the incidence of ROP because of its antioxidant action.
a.
True
b.
False
26.
Which one of the following elaborates chlortetracycline?
a.
Staphylococcus aureus
b.
Streptomyces aureofaciens
c.
Trichophyton rubrum
d.
Malassezia furfur
e.
Staphylococcus epidermidis
27.
Data collected in 2004 by Stanford Hospital and Clinics revealed that 100% of MRSA strains remain susceptible to which one of the following?
a.
Erythromycin
b.
Ciprofloxacin
c.
Ofloxacin
d.
Cephalexin
e.
Doxycycline
28.
Which one of the following manifests noninflammatory cutaneous lesions?
a.
Erythematotelangiectatic rosacea
b.
Papulopustular rosacea
c.
Phymatous rosacea
d.
Ocular rosacea
e.
Granulomatous rosacea
29.
Which one of the following is not a histologic manifestation of rosacea?
a.
Lymphatic ectasia
b.
Elastosis
c.
Presence of pathogenic bacteria
d.
Perivascular and perifollicular leukocytic infiltrates
e.
Vascular ectasia
30.
Which one of the following does not correctly describe Oracea™?
a.
Antimicrobial
b.
Nonantimicrobial
c.
Anti-inflammatory
d.
Submicrobial doxycycline
e.
Effective therapy for rosacea
31.
Which of the following is incorrect?
a.
Patients with obstructive sleep apnea (OSA) have an increased prevalence of coronary artery disease.
b.
Patients with OSA have an increased prevalence of stroke.
c.
Patients with OSA do not have an increase in pulmonary artery pressure.
d.
Patients with OSA have an increased prevalence of sudden cardiac death.
32.
Which of the following is correct?
a.
Patients with OSA have an increased prevalence of hypertension.
b.
Patients with OSA have an increased prevalence of left ventricular hypertrophy.
c.
Patients with OSA have an increased prevalence of congestive heart failure.
d.
All of the above.
33.
Which of the following is incorrect?
a.
Patients with OSA have an increased prevalence of atrial fibrillation.
b.
OSA is not associated with an increase in nocturnal angina pectoris.
c.
Patients with OSA have an increased prevalence of cardiovascular events.
d.
Continuous positive airway pressure is effective in reducing arrhythmias in the majority of patients with OSA.
34.
Which of the following is incorrect?
a.
Patients with OSA do not have an increased prevalence of left ventricular diastolic dysfunction.
b.
Severe OSA is associated with increased mortality.
c.
Hypoxia contributes to systemic hypertension in patients with OSA.
d.
The severity of coronary artery disease is increased in patients with severe OSA.
35.
Which of the following is correct?
a.
Patients with OSA have an increased prevalence of myocardial infarction.
b.
OSA is associated with increased levels of C-reactive protein.
c.
Cardiovascular risk factors should be treated aggressively in patients with OSA.
d.
All of the above.
36.
TRUE or FALSE. Hepatitis C is the major cause of chronic liver disease in the Western World.
a.
True
b.
False
37.
The majority of patients currently infected with Hepatitis C virus in the United States acquired the disease through:
a.
Needle stick inoculation
b.
Sexual transmission
c.
Intravenous drug use
d.
Blood transfusion
e.
Hemodialysis
38.
TRUE or FALSE. Extrahepatic manifestations are seen in about 30% of patients with chronic hepatitis C.
a.
True
b.
False
39.
What percentage of patients infected with Hepatitis C will have chronic disease?
a.
10–20%
b.
30–50%
c.
60–80%
d.
80–100%
40.
All of the following factors accelerate the progression of liver disease in patients with chronic hepatits C virus infection except:
a.
Female sex
b.
HIV disease
c.
Alcohol intake
d.
High viral load
e.
Hepatitis B infection
41.
Brief sex therapy for sex dysfunctions:
a.
Is available clinically and can be learned
b.
Is unknown in the USA
c.
Is considered experimental
d.
Requires surgical procedures
e.
Takes many years to be effective
42.
Sildenafil, tadalafil and vardenafil are:
a.
New diuretics
b.
Selective PDES enzyme inhibitors that allow penile erection with sexplay
c.
Drugs that cause erectile dysfunction
d.
Headache tablets
e.
Have no side-effects
43.
Female aphrodisiacs:
a.
Are easily available today
b.
Are sought out by men only
c.
Are sought by both sexes but rarely work
d.
Are banned in USA
e.
Occur in herbs
44.
Retarded ejaculation may be caused by:
a.
Alcohol excess
b.
Vitamin E
c.
Sildenafil
d.
Anxiety
e.
Cocaine
45.
Premature ejaculation:
a.
Only occurs in men with depression
b.
Is highly responsive to brief sex therapy with/without medication
c.
Only occurs in poorly educated men
d.
Vary rarely causes upset in his partner
e.
Does not send men to their physicians
46.
Erectile dysfunction:
a.
Only occurs in homosexual men
b.
May occur only in tropical areas
c.
Is more frequent in Canada than in the USA
d.
Is a common male sexual symptom
e.
Is always global never situational