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Erschienen in:
01.09.2006 | Erratum
Common variants in MODY genes increase the risk of gestational diabetes mellitus
Erschienen in: Diabetologia | Ausgabe 9/2006
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Unfortunately some of the footnotes in Table 1 of this article were incorrect. The corrected table is reproduced here.
Table 1
Genotype and allele distributions and corresponding odds ratios for GDM
|
SNP (rs number)
|
Genotype or allele
|
GDM n (%)
|
Controls n (%)
|
OR (95% CI) for GDM, additive model/allelic effect
|
OR (95% CI) for GDM, recessive model
|
OR (95% CI) for GDM, dominant model
|
|---|---|---|---|---|---|---|
|
GCK −30G→A
|
GG
|
435 (67.8)
|
889 (72.3)
|
|||
|
(rs1799884)
|
||||||
|
GA
|
181 (28.2)
|
316 (25.7)
|
1.17 (0.94–1.45)
|
|||
|
AA
|
26 (4.0)
|
24 (2.0)a
|
2.21 (1.26–3.90)b
|
2.12 (1.21–3.72)d
|
1.24 (1.01–1.53)e
|
|
|
A
|
233 (18.1)
|
364 (14.8)
|
1.28 (1.06–1.53)c
|
|||
|
HNF1A I27L
|
II
|
242 (39.4)
|
559 (46.1)
|
|||
|
(rs1169288)
|
||||||
|
IL
|
298 (48.5)
|
508 (41.8)
|
1.36 (1.10–1.67)f
|
|||
|
LL
|
74 (12.1)
|
147 (12.1)a
|
1.16 (0.85–1.60)
|
0.99 (0.74–1.34)
|
1.31 (1.08–1.60)e
|
|
|
L
|
446 (36.3)
|
802 (33.0)
|
1.16 (1.001–1.34)c
|
|||
|
HNF4A
|
GG
|
425 (67.8)
|
854 (70.1)
|
|||
|
(rs2144908)
|
||||||
|
GA
|
167 (26.6)
|
316 (25.9)
|
1.06 (0.85–1.32)
|
|||
|
AA
|
35 (5.6)
|
48 (4.0)
|
1.47 (0.93–2.30)
|
1.44 (0.92–2.25)
|
1.12 (0.91–1.37)
|
|
|
A
|
237 (18.9)
|
412 (16.9)
|
1.14 (0.96–1.37)
|
|||
|
HNF4A
|
GG
|
159 (24.7)
|
317 (25.8)
|
|||
|
(rs2425637)
|
||||||
|
GT
|
310 (48.2)
|
617 (50.2)
|
1.00 (0.79–1.27)
|
|||
|
TT
|
174 (27.1)
|
295 (24.0)
|
1.18 (0.90–1.54)
|
1.17 (0.94–1.46)
|
1.06 (0.85–1.32)
|
|
|
T
|
658 (51.2)
|
1207 (49.1)
|
1.09 (0.95–1.24)
|
|||
|
HNF4A
|
GG
|
412 (65.2)
|
791 (65.6)
|
|||
|
(rs1885088)
|
||||||
|
GA
|
199 (31.5)
|
354 (29.4)
|
1.08 (0.87–1.33)
|
|||
|
AA
|
21 (3.3)
|
60 (5.0)
|
0.67 (0.40–1.12)
|
0.66 (0.40–1.09)
|
1.02 (0.83–1.25)
|
|
|
A
|
241 (19.1)
|
474 (19.7)
|
0.96 (0.81–1.14)
|
|||