Erschienen in:
01.08.2012 | Case Report
Concurrent anatomic hemispherectomy and thalamic arteriovenous malformation resection
verfasst von:
Heather J. McCrea, Jared Knopman, Murray Engel, Howard A. Riina, Mark M. Souweidane, Theodore H. Schwartz, Jeffrey P. Greenfield
Erschienen in:
Child's Nervous System
|
Ausgabe 8/2012
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Excerpt
Arteriovenous malformations (AVMs) may present with hemorrhage, neurologic deficits, or seizure. Recent studies have found that of patients with AVMs, approximately 33 % have seizures, and of those patients with seizures, approximately 75 % have generalized tonic–clonic (GTC) seizures [
4,
5]. In a recent study, seizure occurrence was associated with male gender, age <65 years, AVM size greater than 3 cm, and temporal lobe locations [
5]. Complete obliteration of AVMs was associated with freedom from disabling seizure [
5]. AVMs can be treated through microsurgical resection, embolization, radiosurgery, or a combination of these modalities. Deep location, size, and location in eloquent cortex are three factors which may limit surgical resection as they increase surgical morbidity significantly [
11]. The high morbidity of surgical treatment for thalamic AVMs renders them often treated by stereotactic radiosurgery (SRS). A recent study found angiographic obliteration in 55 % of patients undergoing stereotactic radiosurgery with a 13 % rate of permanent radiation-related neurologic deficit; outcome with radiosurgery was linked to age of patient, AVM volume, and AVM location [
12]. …
