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Critical Care
Erschienen in: Critical Care 6/2005

01.12.2005 | Commentary

Conflicting clinical trial data: a lesson from albumin

verfasst von: Greg Martin

Erschienen in: Critical Care | Ausgabe 6/2005

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Abstract

Albumin is a frequently prescribed drug in hospitalized patients, and its effect on clinical outcomes has been scrutinized in recent years. Data from meta-analyses has suggested harm related to albumin therapy in critically ill patients, and new observational data are consistent with these results. However, appropriately powered randomized, controlled trials have shown albumin to be safe in broad groups of critically ill patients. This article will discuss the reasons for differences between observational and controlled trial data, and the implications for future albumin use and clinical research.
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Metadaten
Titel
Conflicting clinical trial data: a lesson from albumin
verfasst von
Greg Martin
Publikationsdatum
01.12.2005
Verlag
BioMed Central
Erschienen in
Critical Care / Ausgabe 6/2005
Elektronische ISSN: 1364-8535
DOI
https://doi.org/10.1186/cc3931

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