Skip to main content
Erschienen in: The International Journal of Cardiovascular Imaging 11/2016

09.08.2016 | Original Paper

Coronary bifurcation stent morphology in dual-source CT: validation with micro-CT

verfasst von: Hye-Joung Eom, Dong Hyun Yang, Young-Hak Kim, Jae-Hyung Roh, Jihoon Kweon, Soo-Jin Kang, Namkug Kim, Joon-Won Kang, Tae-Hwan Lim

Erschienen in: The International Journal of Cardiovascular Imaging | Ausgabe 11/2016

Einloggen, um Zugang zu erhalten

Abstract

The aim of this study is to analyze post-bifurcation coronary stent morphology in vitro using dual-source CT and validate those findings using micro-CT. Nine silicon coronary artery phantoms simulating main branch (MB) and side branch (SB) were prepared using a 3-D printer. After bifurcation stenting using Crush, Culotte, and T-stenting technique, in vitro CT imaging was conducted using both dual-source CT and micro-CT. Morphological change of the bifurcation stent including crushed segment and floating stent strut were evaluated. Dual-source CT was able to demonstrate morphologic changes of bifurcation stents and was comparable to micro-CT. In stents with Crush and T-stenting methods, crushed segment appeared denser and thicker than other stent parts and was located at MB side in all phantoms. Floating strut was observed in half of the phantoms with Crush technique and all phantoms with T-stenting. Parameters measured in both dual-source CT and micro-CT showed good correlation and high agreement (limits of agreement and correlation for length, perimeter and area, 0.3 ± 3.5, 0.5 ± 2.1 mm, and 0.0 ± 1.5 mm², r = 0.76, 0.92, and 0.91). The morphology of post-bifurcation stent on dual-source CT correlates well with that of micro-CT in the coronary artery phantom. Coronary CT angiography may be a feasible method for the evaluation of stent morphology in patients who underwent bifurcation stenting.
Literatur
1.
Zurück zum Zitat Latib A, Colombo A, Sangiorgi GM (2009) Bifurcation stenting: current strategies and new devices. Heart 95:495–504CrossRefPubMed Latib A, Colombo A, Sangiorgi GM (2009) Bifurcation stenting: current strategies and new devices. Heart 95:495–504CrossRefPubMed
2.
Zurück zum Zitat Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O’Shaughnessy C et al (2003) Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 349:1315–1323CrossRefPubMed Moses JW, Leon MB, Popma JJ, Fitzgerald PJ, Holmes DR, O’Shaughnessy C et al (2003) Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. N Engl J Med 349:1315–1323CrossRefPubMed
3.
Zurück zum Zitat Maeng M, Holm NR, Erglis A, Kumsars I, Niemela M, Kervinen K et al (2013) Long-term results after simple versus complex stenting of coronary artery bifurcation lesions: Nordic bifurcation Study 5-year follow-up results. J Am Coll Cardiol 62:30–34CrossRefPubMed Maeng M, Holm NR, Erglis A, Kumsars I, Niemela M, Kervinen K et al (2013) Long-term results after simple versus complex stenting of coronary artery bifurcation lesions: Nordic bifurcation Study 5-year follow-up results. J Am Coll Cardiol 62:30–34CrossRefPubMed
4.
Zurück zum Zitat Steigen TK, Maeng M, Wiseth R, Erglis A, Kumsars I, Narbute I et al (2006) Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study. Circulation 114:1955–1961CrossRefPubMed Steigen TK, Maeng M, Wiseth R, Erglis A, Kumsars I, Narbute I et al (2006) Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study. Circulation 114:1955–1961CrossRefPubMed
5.
Zurück zum Zitat Erglis A, Kumsars I, Niemela M, Kervinen K, Maeng M, Lassen JF et al (2009) Randomized comparison of coronary bifurcation stenting with the crush versus the culotte technique using sirolimus eluting stents: the Nordic stent technique study. Circ Cardiovasc Interv 2:27–34CrossRefPubMed Erglis A, Kumsars I, Niemela M, Kervinen K, Maeng M, Lassen JF et al (2009) Randomized comparison of coronary bifurcation stenting with the crush versus the culotte technique using sirolimus eluting stents: the Nordic stent technique study. Circ Cardiovasc Interv 2:27–34CrossRefPubMed
6.
Zurück zum Zitat Ormiston JA, Currie E, Webster MW, Kay P, Ruygrok PN, Stewart JT et al (2004) Drug-eluting stents for coronary bifurcations: insights into the crush technique. Catheter Cardiovasc Interv 63:332–336CrossRefPubMed Ormiston JA, Currie E, Webster MW, Kay P, Ruygrok PN, Stewart JT et al (2004) Drug-eluting stents for coronary bifurcations: insights into the crush technique. Catheter Cardiovasc Interv 63:332–336CrossRefPubMed
7.
Zurück zum Zitat Costa MA, Sabate M, Angiolillo DJ, Jimenez-Quevedo P, Teirstein P, Carter A et al (2006) Intravascular ultrasound characterization of the “black hole” phenomenon after drug-eluting stent implantation. Am J Cardiol 97:203–206CrossRefPubMed Costa MA, Sabate M, Angiolillo DJ, Jimenez-Quevedo P, Teirstein P, Carter A et al (2006) Intravascular ultrasound characterization of the “black hole” phenomenon after drug-eluting stent implantation. Am J Cardiol 97:203–206CrossRefPubMed
8.
Zurück zum Zitat Nasu K, Tsuchikane E, Katoh O, Vince DG, Virmani R, Surmely JF et al (2006) Accuracy of in vivo coronary plaque morphology assessment: a validation study of in vivo virtual histology compared with in vitro histopathology. J Am Coll Cardiol 47:2405–2412CrossRefPubMed Nasu K, Tsuchikane E, Katoh O, Vince DG, Virmani R, Surmely JF et al (2006) Accuracy of in vivo coronary plaque morphology assessment: a validation study of in vivo virtual histology compared with in vitro histopathology. J Am Coll Cardiol 47:2405–2412CrossRefPubMed
9.
Zurück zum Zitat Nikolaou K, Knez A, Rist C, Wintersperger BJ, Leber A, Johnson T et al (2006) Accuracy of 64-MDCT in the diagnosis of ischemic heart disease. Am J Roentgenol 187:111–117CrossRef Nikolaou K, Knez A, Rist C, Wintersperger BJ, Leber A, Johnson T et al (2006) Accuracy of 64-MDCT in the diagnosis of ischemic heart disease. Am J Roentgenol 187:111–117CrossRef
10.
Zurück zum Zitat Lim HB, Hur G, Kim SY, Kim YH, Kwon SU, Lee WR et al (2008) Coronary stent fracture: detection with 64-section multidetector CT angiography in patients and in vitro. Radiology 249:810–819CrossRefPubMed Lim HB, Hur G, Kim SY, Kim YH, Kwon SU, Lee WR et al (2008) Coronary stent fracture: detection with 64-section multidetector CT angiography in patients and in vitro. Radiology 249:810–819CrossRefPubMed
11.
Zurück zum Zitat Chung MS, Yang DH, Kim YH, Roh JH, Song J, Kang JW et al (2015) Stent fracture and longitudinal compression detected on coronary CT angiography in the first- and new-generation drug-eluting stents. Int J Cardiovasc Imaging. doi:10.1007/s10554-015-0798-4 (E-pub ahead of print) Chung MS, Yang DH, Kim YH, Roh JH, Song J, Kang JW et al (2015) Stent fracture and longitudinal compression detected on coronary CT angiography in the first- and new-generation drug-eluting stents. Int J Cardiovasc Imaging. doi:10.​1007/​s10554-015-0798-4 (E-pub ahead of print)
12.
Zurück zum Zitat Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Chan PH et al (2012) Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations: lessons from micro-computed tomography and computational simulations. JACC Cardiovasc Interv 5:47–56CrossRefPubMed Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Chan PH et al (2012) Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations: lessons from micro-computed tomography and computational simulations. JACC Cardiovasc Interv 5:47–56CrossRefPubMed
13.
Zurück zum Zitat Foin N, Torii R, Alegria E, Sen S, Petraco R, Nijjer S et al (2013) Location of side branch access critically affects results in bifurcation stenting: insights from bench modeling and computational flow simulation. Int J Cardiol 168:3623–3628CrossRefPubMed Foin N, Torii R, Alegria E, Sen S, Petraco R, Nijjer S et al (2013) Location of side branch access critically affects results in bifurcation stenting: insights from bench modeling and computational flow simulation. Int J Cardiol 168:3623–3628CrossRefPubMed
14.
Zurück zum Zitat Murasato Y (2007) Impact of three-dimensional characteristics of the left main coronary artery bifurcation on outcome of crush stenting. Catheter Cardiovasc Interv 69:248–256CrossRefPubMed Murasato Y (2007) Impact of three-dimensional characteristics of the left main coronary artery bifurcation on outcome of crush stenting. Catheter Cardiovasc Interv 69:248–256CrossRefPubMed
15.
Zurück zum Zitat Di Vito L, Yoon JH, Kato K, Yonetsu T, Vergallo R, Costa M et al (2014) Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses. Coron Artery Dis 25:172–185CrossRefPubMed Di Vito L, Yoon JH, Kato K, Yonetsu T, Vergallo R, Costa M et al (2014) Comprehensive overview of definitions for optical coherence tomography-based plaque and stent analyses. Coron Artery Dis 25:172–185CrossRefPubMed
16.
Zurück zum Zitat Pracon R, Opolski MP, Mintz GS, Pregowski J, Kruk M, Popma JJ et al (2014) Serial intravascular ultrasound analysis of stent strut distribution and fracture: an integrated analysis of the taxus IV, V, and VI trials. J Invasive Cardiol 26:501–511PubMed Pracon R, Opolski MP, Mintz GS, Pregowski J, Kruk M, Popma JJ et al (2014) Serial intravascular ultrasound analysis of stent strut distribution and fracture: an integrated analysis of the taxus IV, V, and VI trials. J Invasive Cardiol 26:501–511PubMed
17.
Zurück zum Zitat Kyono H, Guagliumi G, Sirbu V, Rosenthal N, Tahara S, Musumeci G et al (2010) Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations. EuroIntervention 6:69–77CrossRefPubMed Kyono H, Guagliumi G, Sirbu V, Rosenthal N, Tahara S, Musumeci G et al (2010) Optical coherence tomography (OCT) strut-level analysis of drug-eluting stents (DES) in human coronary bifurcations. EuroIntervention 6:69–77CrossRefPubMed
18.
Zurück zum Zitat Taylor AJ, Cerqueira M, Hodgson JM, Mark D, Min J, O’Gara P et al (2010) ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. J Cardiovasc Comput Tomogr 4:407 e401–433CrossRef Taylor AJ, Cerqueira M, Hodgson JM, Mark D, Min J, O’Gara P et al (2010) ACCF/SCCT/ACR/AHA/ASE/ASNC/NASCI/SCAI/SCMR 2010 appropriate use criteria for cardiac computed tomography. J Cardiovasc Comput Tomogr 4:407 e401–433CrossRef
19.
Zurück zum Zitat Jensen JS, Galloe A, Lassen JF, Erglis A, Kumsars I, Steigen TK et al (2008) Safety in simple versus complex stenting of coronary artery bifurcation lesions. The Nordic Bifurcation Study 14-month follow-up results. EuroIntervention 4:229–233CrossRefPubMed Jensen JS, Galloe A, Lassen JF, Erglis A, Kumsars I, Steigen TK et al (2008) Safety in simple versus complex stenting of coronary artery bifurcation lesions. The Nordic Bifurcation Study 14-month follow-up results. EuroIntervention 4:229–233CrossRefPubMed
20.
Zurück zum Zitat Hildick-Smith D, de Belder AJ, Cooter N, Curzen NP, Clayton TC, Oldroyd KG et al (2010) Randomized trial of simple versus complex drug-eluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation 121:1235–1243CrossRefPubMed Hildick-Smith D, de Belder AJ, Cooter N, Curzen NP, Clayton TC, Oldroyd KG et al (2010) Randomized trial of simple versus complex drug-eluting stenting for bifurcation lesions: the British Bifurcation Coronary Study: old, new, and evolving strategies. Circulation 121:1235–1243CrossRefPubMed
21.
Zurück zum Zitat Chiastra C, Morlacchi S, Gallo D, Morbiducci U, Cardenes R, Larrabide I et al (2013) Computational fluid dynamic simulations of image-based stented coronary bifurcation models. J R Soc Interface 10:20130193CrossRefPubMedPubMedCentral Chiastra C, Morlacchi S, Gallo D, Morbiducci U, Cardenes R, Larrabide I et al (2013) Computational fluid dynamic simulations of image-based stented coronary bifurcation models. J R Soc Interface 10:20130193CrossRefPubMedPubMedCentral
22.
Zurück zum Zitat Williams AR, Koo BK, Gundert TJ, Fitzgerald PJ, LaDisa JF Jr (2010) Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J Appl Physiol 109:532–540CrossRefPubMed Williams AR, Koo BK, Gundert TJ, Fitzgerald PJ, LaDisa JF Jr (2010) Local hemodynamic changes caused by main branch stent implantation and subsequent virtual side branch balloon angioplasty in a representative coronary bifurcation. J Appl Physiol 109:532–540CrossRefPubMed
Metadaten
Titel
Coronary bifurcation stent morphology in dual-source CT: validation with micro-CT
verfasst von
Hye-Joung Eom
Dong Hyun Yang
Young-Hak Kim
Jae-Hyung Roh
Jihoon Kweon
Soo-Jin Kang
Namkug Kim
Joon-Won Kang
Tae-Hwan Lim
Publikationsdatum
09.08.2016
Verlag
Springer Netherlands
Erschienen in
The International Journal of Cardiovascular Imaging / Ausgabe 11/2016
Print ISSN: 1569-5794
Elektronische ISSN: 1875-8312
DOI
https://doi.org/10.1007/s10554-016-0953-6

Weitere Artikel der Ausgabe 11/2016

The International Journal of Cardiovascular Imaging 11/2016 Zur Ausgabe

Screening-Mammografie offenbart erhöhtes Herz-Kreislauf-Risiko

26.04.2024 Mammografie Nachrichten

Routinemäßige Mammografien helfen, Brustkrebs frühzeitig zu erkennen. Anhand der Röntgenuntersuchung lassen sich aber auch kardiovaskuläre Risikopatientinnen identifizieren. Als zuverlässiger Anhaltspunkt gilt die Verkalkung der Brustarterien.

Niedriger diastolischer Blutdruck erhöht Risiko für schwere kardiovaskuläre Komplikationen

25.04.2024 Hypotonie Nachrichten

Wenn unter einer medikamentösen Hochdrucktherapie der diastolische Blutdruck in den Keller geht, steigt das Risiko für schwere kardiovaskuläre Ereignisse: Darauf deutet eine Sekundäranalyse der SPRINT-Studie hin.

Therapiestart mit Blutdrucksenkern erhöht Frakturrisiko

25.04.2024 Hypertonie Nachrichten

Beginnen ältere Männer im Pflegeheim eine Antihypertensiva-Therapie, dann ist die Frakturrate in den folgenden 30 Tagen mehr als verdoppelt. Besonders häufig stürzen Demenzkranke und Männer, die erstmals Blutdrucksenker nehmen. Dafür spricht eine Analyse unter US-Veteranen.

Adipositas-Medikament auch gegen Schlafapnoe wirksam

24.04.2024 Adipositas Nachrichten

Der als Antidiabetikum sowie zum Gewichtsmanagement zugelassene Wirkstoff Tirzepatid hat in Studien bei adipösen Patienten auch schlafbezogene Atmungsstörungen deutlich reduziert, informiert der Hersteller in einer Vorab-Meldung zum Studienausgang.

Update Kardiologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.