a (model 1) | Regression coefficient β | Multiple linear regression 95% CI | p-value |
Baseline eGFR (mL/ml/1.73 m22) | - 0.20 | - 0.38 - − 0.02 | 0.03 |
Baseline Haemoglobin (mg/dL) | 0.51 | - 0.86 - 1.89 | 0.46 |
Tumour diameter (cm) | 0.67 | - 0.43 - 1.76 | 0.24 |
Tumour locus central (ref.) vs. peripheral | 0.43 | - 3.80 - 4.67 | 0.84 |
Surgical approach LNSS (ref.) vs. ONSS | - 13.48 | - 17.65 - − 9.32 | < 0.001 |
Sex male (ref.) vs. female | - 3.28 | - 7.80 - 1.25 | 0.16 |
Age (years) | - 0.17 | - 0.36 - 0.01 | 0.06 |
BMI (kg/m2) | - 0.88 | - 1.36 - − 0.41 | < 0.001 |
Hypertension no (ref.) vs. yes | - 0.78 | - 4.75 - 3.18 | 0.70 |
Ischaemia time (min) | - 0.27 | - 0.41 - − 0.13 | < 0.001 |
Operative time (min) | - 0.06 | - 0.09 - − 0.03 | < 0.001 |
Preoperative ureter stenting no (ref.) vs. yes | - 0.46 | - 5.64 - 4.71 | 0.86 |
Intraoperative blood transfusions no (ref.) vs. yes | - 3.29 | - 11.91 - 5.33 | 0.45 |
Postoperative complications no (ref.) vs. yes | - 3.36 | - 8.42 - 1.70 | 0.19 |
Clavien-Dindo score < 3 (ref.) vs. ≥ 3 | - 10.98 | - 18.47 - − 3.48 | 0.004 |
b (model 2) | Regression coefficient β | Multiple linear regression 95% CI | p-value |
Baseline eGFR (mL/ml/1.73 m22) | - 0.29 | - 0.49 - − 0.09 | 0.005 |
Baseline Haemoglobin (mg/dL) | - 0.32 | - 1.95 - 1.31 | 0.70 |
Relative change of eGFR from baseline at time A (%) | 0.18 | 0.03 - 0.33 | 0.02 |
AKI 48 h p.o. no (ref.) vs. yes | - 2.11 | - 9.01 - 4.79 | 0.55 |
Tumour diameter (cm) | - 1.76 | - 2.87 - − 0.66 | 0.002 |
Tumour locus central (ref.) vs. peripheral | - 0.30 | - 5.14 - 4.54 | 0.90 |
Surgical approach LNSS (ref.) vs. ONSS | 1.13 | - 4.17 - − 6.44 | 0.67 |
Sex male (ref.) vs. female | 1.63 | - 3.43 - 6.70 | 0.53 |
Age (years) | - 0.10 | - 0.33 - 0.13 | 0.40 |
BMI (kg/m2) | 0.15 | - 0.39 - 0.70 | 0.58 |
Hypertension no (ref.) vs. yes | - 2.11 | - 6.82 - 2.60 | 0.38 |
Ischaemia time (min) | 0.03 | - 0.14 - 0.21 | 0.72 |
Operative time (min) | 0.01 | - 0.03 - 0.05 | 0.54 |
Preoperative ureter stenting no (ref.) vs. yes | - 4.35 | - 10.46 - 1.77 | 0.16 |
Intraoperative blood transfusions no (ref.) vs. yes | 4.12 | - 6.29 - 14.52 | 0.44 |
Postoperative complications no (ref.) vs. yes | 1.20 | - 4.77 - 7.18 | 0.69 |
Clavien-Dindo score < 3 (ref.) vs. ≥ 3 | 4.43 | - 4.28 - 13.14 | 0.32 |
c (model 3) | OR | Multiple logistic regression 95% CI | p-value |
Baseline eGFR (mL/ml/1.73 m22) | 0.99 | 0.96 - 1.01 | 0.30 |
Baseline Haemoglobin (mg/dl) | 0.85 | 0.70 - 1.03 | 0.10 |
Tumour diameter (cm) | 0.94 | 0.81 - 1.08 | 0.35 |
Tumour locus central (ref.) vs. peripheral | 1.20 | 0.70 - 2.05 | 0.51 |
Surgical approach LNSS (ref.) vs. ONSS | 3.87 | 2.17 - 6.92 | < 0.001 |
Sex male (ref.) vs. female | 2.51 | 1.35 - 4.67 | 0.004 |
Age (years) | 1.01 | 0.99 - 1.04 | 0.26 |
BMI (kg/m2) | 1.13 | 1.06 - 1.21 | < 0.001 |
Hypertension no (ref.) vs. yes | 1.05 | 0.63 - 1.74 | 0.85 |
Ischaemia time (min) | 1.02 | 1.00 - 1.04 | 0.046 |
Operative time (min) | 1.01 | 1.00 - 1.01 | 0.002 |
Preoperative ureter stenting no (ref.) vs. yes | 0.92 | 0.46 - 1.83 | 0.81 |
Intraoperative blood transfusions no (ref.) vs. yes | 0.73 | 0.22 - 2.45 | 0.61 |
Postoperative complications no (ref.) vs. yes | 1.79 | 0.92 - 3.48 | 0.08 |
Clavien-Dindo score < 3 (ref.) vs. ≥ 3 | 2.14 | 0.68 - 6.72 | 0.19 |
d (model 4) | OR | Multiple logistic regression 95% CI | p-value |
Baseline eGFR (mL/ml/1.73 m2) | 0.89 | 0.85 - 0.92 | < 0.001 |
Baseline Haemoglobin (mg/dL) | 0.99 | 0.73 - 1.35 | 0.95 |
Relative change of eGFR from baseline at time A (%) | 0.98 | 0.98 - 1.01 | 0.12 |
AKI 48 h p.o. no (ref.) vs. yes | 1.23 | 0.39 - 3.85 | 0.72 |
Tumour diameter (cm) | 0.93 | 0.71 - 1.21 | 0.58 |
Tumour locus central (ref.) vs. peripheral | 1.35 | 0.56 - 3.15 | 0.49 |
Surgical approach LNSS (ref.) vs. ONSS | 1.69 | 0.67 - 4.24 | 0.26 |
Sex male (ref.) vs. female | 0.63 | 0.24 - 1.67 | 0.35 |
Age (years) | 0.99 | 0.95 - 1.04 | 0.75 |
BMI (kg/m2) | 0.97 | 0.87 - 1.07 | 0.50 |
Hypertension no (ref.) vs. yes | 1.62 | 0.66 - 4.00 | 0.29 |
Ischaemia time (min) | 1.01 | 0.98 - 1.04 | 0.55 |
Operative time (min) | 1.00 | 0.99 - 1.01 | 0.86 |
Preoperative ureter stenting no (ref.) vs. yes | 1.26 | 0.41 - 3.86 | 0.68 |
Intraoperative blood transfusions no (ref.) vs. yes | 0.95 | 0.08 - 11.05 | 0.97 |
Postoperative complications no (ref.) vs. yes | 0.67 | 0.22 - 2.00 | 0.47 |
Clavien-Dindo score < 3 (ref.) vs. ≥ 3 | 1.37 | 0.22 - 8.41 | 0.73 |
Open Access 01.12.2019 | Correction
Correction to: Outcome of kidney function after ischaemic and zero-ischaemic laparoscopic and open nephron-sparing surgery for renal cell cancer
Erschienen in: BMC Nephrology | Ausgabe 1/2019