Skip to main content
Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging 4/2022

08.11.2021 | COVID-19 | Image of the Month Zur Zeit gratis

68Ga-DOTATOC digital-PET imaging of inflammatory cell infiltrates in myocarditis following COVID-19 vaccination

verfasst von: Caroline Boursier, Elodie Chevalier, Laura Filippetti, Laetitia Imbert, Veronique Roch, Olivier Huttin, Marine Claudin, Pierre-Yves Marie

Erschienen in: European Journal of Nuclear Medicine and Molecular Imaging | Ausgabe 4/2022

Einloggen, um Zugang zu erhalten

Excerpt

Acute myocarditis was recently reported after mRNA COVID-19 vaccination. Here we present images from two male (18 and 21 years old) patients that were recorded with a digital-PET/CT system (Vereos, Philips) 1 h after the injection of 2 MBq/kg of 68 Ga-DOTATOC, as part of an ongoing clinical study (NCT03347760 on ClinicalTrials.gov). Both patients experienced myocarditis 2 to 3 days after the second dose of an mRNA COVID-19 vaccine (Moderna and Pfizer, respectively) and fulfilled the cardiovascular magnetic resonance 2018 Lake Louise criteria for myocarditis, associated with increased plasma troponin (peak troponin: 771 ng/L and 10 830 ng/L) but normal plasma fibrinogen. Plasma C-reactive protein was increased in the 21-year-old patient (41 mg/L). …
Anhänge
Nur mit Berechtigung zugänglich
Literatur
1.
Zurück zum Zitat Lichtenauer-Kaligis EG, Dalm VA, Oomen SP, Mooij DM, van Hagen PM, Lamberts SW, et al. Differential expression of somatostatin receptor subtypes in human peripheral blood mononuclear cell subsets. Eur J Endocrinol. 2004;150(4):565–77.CrossRef Lichtenauer-Kaligis EG, Dalm VA, Oomen SP, Mooij DM, van Hagen PM, Lamberts SW, et al. Differential expression of somatostatin receptor subtypes in human peripheral blood mononuclear cell subsets. Eur J Endocrinol. 2004;150(4):565–77.CrossRef
2.
Zurück zum Zitat Lapa C, Reiter T, Li X, Werner RA, Samnick S, Jahns R, et al. Imaging of myocardial inflammation with somatostatin receptor based PET/CT - a comparison to cardiac MRI. Int J Cardiol. 2015;194:44–9.CrossRef Lapa C, Reiter T, Li X, Werner RA, Samnick S, Jahns R, et al. Imaging of myocardial inflammation with somatostatin receptor based PET/CT - a comparison to cardiac MRI. Int J Cardiol. 2015;194:44–9.CrossRef
3.
Zurück zum Zitat Pizarro C, Kluenker F, Dabir D, Thomas D, Gaertner FC, Essler M, et al. Cardiovascular magnetic resonance imaging and clinical performance of somatostatin receptor positron emission tomography in cardiac sarcoidosis. ESC Heart Fail. 2018;5:249–61.CrossRef Pizarro C, Kluenker F, Dabir D, Thomas D, Gaertner FC, Essler M, et al. Cardiovascular magnetic resonance imaging and clinical performance of somatostatin receptor positron emission tomography in cardiac sarcoidosis. ESC Heart Fail. 2018;5:249–61.CrossRef
4.
Zurück zum Zitat Amini A, Dehdar F, Jafari E, Gholamrezanezhad A, Assadi M. Somatostatin receptor scintigraphy in a patient with myocarditis. Mol Imaging Radionucl Ther. 2021;30:50–3.CrossRef Amini A, Dehdar F, Jafari E, Gholamrezanezhad A, Assadi M. Somatostatin receptor scintigraphy in a patient with myocarditis. Mol Imaging Radionucl Ther. 2021;30:50–3.CrossRef
Metadaten
Titel
68Ga-DOTATOC digital-PET imaging of inflammatory cell infiltrates in myocarditis following COVID-19 vaccination
verfasst von
Caroline Boursier
Elodie Chevalier
Laura Filippetti
Laetitia Imbert
Veronique Roch
Olivier Huttin
Marine Claudin
Pierre-Yves Marie
Publikationsdatum
08.11.2021
Verlag
Springer Berlin Heidelberg
Schlagwort
COVID-19
Erschienen in
European Journal of Nuclear Medicine and Molecular Imaging / Ausgabe 4/2022
Print ISSN: 1619-7070
Elektronische ISSN: 1619-7089
DOI
https://doi.org/10.1007/s00259-021-05609-4

Weitere Artikel der Ausgabe 4/2022

European Journal of Nuclear Medicine and Molecular Imaging 4/2022 Zur Ausgabe