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15.09.2020 | COVID-19 | Review Zur Zeit gratis

Coronavirus disease 2019 (COVID-19) during pregnancy in patients with rheumatic diseases

Erschienen in: Rheumatology International | Ausgabe 11/2020

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Abstract

The novel coronavirus outbreak induces many concerns about the management of pregnancy, as well as rheumatic and musculoskeletal diseases. The very rapid spread of the infection throughout all inhabited continents leads to a fast-growing number of infected with SARS-CoV-2 and requires answers and special recommendations to the most vulnerable group of people: pregnant woman and patients on immunomodulatory or immunosuppressive treatment. A systematic literature search was performed in Embase, MEDLINE, and Scopus database for studies describing COVID-19 infection in pregnant women diagnosed with rheumatic and musculoskeletal diseases. From the 1,115 initially identified articles, we selected 29 publications in the English language, from which 18 were eligible according to the inclusion criteria. Limited number of cases and further researches are required to evaluate the risk of transmission of SARS-CoV-2 from mother to her infant as well as clinical features of infection in pregnant women. The conclusions of different authors, despite the small number of cases, suggest that there is no vertical transmission in women diagnosed with COVID-19 pneumonia. Although the World Health Organization recently reported that pregnant patients do not have a higher risk of infection than the rest of the population, Royal College of Obstetricians & Gynecologists and The Royal College of Midwives for COVID-19 infection in pregnancy published Guidelines for pregnant women with suspected SARS-CoV-2 infection.

Considerations about patients with rheumatic diseases on the immunosuppressive treatment required European League Against Rheumatism, American College of Rheumatology, British Society for Rheumatology, and Australian Rheumatology Association to publish recommendations for patients with rheumatic diseases and COVID-19. These algorithms are very important to the medical society, but many concerns, absence of experience, and many questions are still unanswered and need time to be resolved and proceed successfully in this global pandemic situation.

Li Q, Guan X, Wu P et al (2020) Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med 382:1199–1207. https://doi.org/10.1056/NEJMoa2001316CrossRefPubMedPubMedCentral

Huang C, Wang Y, Li X et al (2020) Clinical features of patients infected with 2019 novel coronavirus in Wuhan China. Lancet 395:497–506CrossRefPubMedPubMedCentral

WHO. Coronavirus disease (COVID-19) situation report 82 https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200411-sitrep-82-covid-19.pdf?sfvrsn=74a5d15_2

The COVID-19 Global Rheumatology Alliance. https://rheum-covid.org

The COVID-19 Global Rheumatology Alliance Global Registry. https://mailchi.mp/a6dc80671481/just-launched-the-covid-19-global-rheumatology-registry-4810762

Coronavirus (COVID-19) infection and pregnancy. Version 7 (2020) Guidance for healthcare professionals on coronavirus (COVID-19) infection in pregnancy, published by the RCOG, Royal College of Midwives, Royal College of Paediatrics and Child Health, Public Health England and Health Protection Scotland. https://www.rcog.org.uk/globalassets/documents/guidelines/2020-04-09-coronavirus-covid-19-infection-in-pregnancy.pdf Accessed: 9 Apr 2020

Zhang W, Du R-H, Li B et al (2020) (2020) Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerg Microbes Infect 9:386–389. https://doi.org/10.1080/22221751.2020.1729071CrossRefPubMedPubMedCentral

Yongwen L, Kai Y (2020) Management of pregnant women infected with COVID-19. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30191-2CrossRef

Martinez-Portilla RJ, Gonce A, Hawkins – Villarreal A, Figueras F (2020) A Spanish – translated clinical algorithm for management of suspected SARS-CoV-2 infection in pregnant women. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30285-1CrossRefPubMedPubMedCentral

10.

Favre G, Pomar L, Qi X, Nielsen-Saines K, Musso D, Baud D (2020) Guidelines for pregnant women with suspected SARS-CoV-2 infection. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30157-2CrossRefPubMedPubMedCentral

11.

Chen H, Guo J, Wang C et al (2020) Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. The Lancet 395:809–815. https://doi.org/10.1016/S0140-6736(20)30360-3CrossRef

12.

Di Mascio D, Khalil A, Saccone G et al (2020) Outcome of Coronavirus spectrum infections (SARS, MERS, COVID) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. https://doi.org/10.1016/j.ajogmf.2020.100107CrossRefPubMedPubMedCentral

13.

Misra DP, Agarwal V, Gasparyan AY, Zimba O (2020) Rheumatologists' perspective on coronavirus disease 19 (COVID-19) and potential therapeutic targets. Clin Rheumatol 39:2055–2062. https://doi.org/10.1007/s10067-020-05073-9CrossRefPubMed

14.

Favalli EG, Ingegnoli F, De Lucia O et al (2020) COVID-19 infection and rheumatoid arthritis: Faraway, so close! Autoimmun Rev 19(5):102523. https://doi.org/10.1016/j.autrev.2020.102523CrossRefPubMedPubMedCentral

15.

Onuora S (2020) New data emerging on outcomes for patients with COVID-19 and rheumatic diseases. Nat Rev Rheumatol 16:407. https://doi.org/10.1038/s41584-020-0463-8CrossRefPubMedPubMedCentral

16.

Huang Y et al (2020) Clinical characteristics of 17 patients with COVID-19 and systemic autoimmune diseases: a retrospective study. Ann Rheum Dis. https://doi.org/10.1136/annrheumdis-2020-217425CrossRefPubMed

17.

Yang H, Wang C, Poon LC (2020) Novel coronavirus infection and pregnancy. Ultrasound Obstet Gynecol 55:435–437. https://doi.org/10.1002/uog.22006CrossRefPubMedPubMedCentral

18.

World Health Organization. Q&A on coronaviruses (COVID-19). https://www.who.int/news-room/q-a-detail/q-a-coronaviruses. Accessed: 17 Apr 2020

19.

Centers for Disease Control and Prevention. Coronavirus disease 2019 (COVID-19). Pregnancy and Breastfeeding. https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/pregnancy-breastfeeding.html Accessed: 24 Apr 2020

20.

Gasparyan AY, Ayvazyan L, Blackmore H, Kitas GD (2011) Writing a narrative biomedical review: considerations for authors, peer reviewers, and editors. Rheumatol Int 31(11):1409–1417. https://doi.org/10.1007/s00296-011-1999-3CrossRefPubMed

21.

Wang X, Zhou Z, Zhang J, Zhu F, Tang Y, Shen X (2020) A case of 2019 Novel Coronavirus in a pregnant woman with preterm delivery. Clin Infect Dis. https://doi.org/10.1093/cid/ciaa200CrossRefPubMedPubMedCentral

22.

Li Y, Zhao R, Zheng S et al (2020) Lack of vertical transmission of severe acute respiratory syndrome coronavirus 2 China. Emerg Infect Dis. https://doi.org/10.3201/eid2606.200287CrossRefPubMedPubMedCentral

23.

Saccone G, Carbone F, Zullo F (2020) The novel coronavirus (2019-nCoV) in pregnancy: what we need to know. Eur J Obstetr Gynecol Reprod Biol. https://doi.org/10.1016/j.ejogrb.2020.04.006CrossRef

24.

Liu D, Li L, Wu X et al. (2020). Pregnancy and Perinatal Outcomes of Women with COVID-19 Pneumonia: A Preliminary Analysis. Available at SSRN: https://ssrn.com/abstract=3548758. Accessed: 29 Feb 2020

25.

Sutton D, Fuchs K, D’Alton M, Goffman D (2020) Universal screening for SARS-CoV-2 in Women admitted for delivery. N Engl J Med. https://doi.org/10.1056/NEJMc2009316CrossRefPubMedPubMedCentral

26.

Meselson M (2020) Droplets and aerosols in the transmission of SARS-CoV-2. N Engl J Med. https://doi.org/10.1056/NEJMc2009316CrossRefPubMedPubMedCentral

27.

Nan Yu, Li Wei, Qingling K et al (2020) Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-center, descriptive study. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30176-6CrossRef

28.

Zhu H, Wang L, Fang C, et al (2020) Clinical analysis of neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 9(1):51–60 https://doi.org/10.21037/tp.2020.02.06

29.

Breslin N, Baptiste C, Gyamfi-Bannerman C et al (2020) COVID-19 infection among asymptomatic and symptomatic pregnant women: Two weeks of confirmed presentations to an affiliated pair of New York City hospitals. AJOG MFM 2(2):100118. https://doi.org/10.1016/j.ajogmf.2020.100118CrossRefPubMed

30.

Dong L, Tian J, He S et al (2020) Possible vertical transmission of SARS-CoV-2 from an infected mother to her newborn. JAMA. https://doi.org/10.1001/jama.2020.4621CrossRefPubMedPubMedCentral

31.

Zeng H, Xu C, Fan J et al (2020) Antibodies in infants born to mothers with COVID-19 pneumonia. JAMA 323(18):1848–1849. https://doi.org/10.1001/jama.2020.4861CrossRefPubMedPubMedCentral

32.

Yudin MH, Steele DM, Sgro MD, Read SE, Kopplin P, Gough KA (2005) Severe acute respiratory syndrome in pregnancy. Obstet Gynecol 105:124–127. https://doi.org/10.1097/01.AOG.0000151598.49129.deCrossRefPubMed

33.

Gasparyan AY, Misra DP, Yessirkepov M, Zimba O (2020) Perspectives of immune therapy in coronavirus disease 2019. J Korean Med Sci 35(18):e176. https://doi.org/10.3346/jkms.2020.35.e176CrossRefPubMedPubMedCentral

34.

Wu Z, McCoogan JM (2020) Characteristics of and important lessons from the coronavirus disease 2019 (CPVOD-19) outbreak in China: summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention. JAMA 323(13):1239–1242. https://doi.org/10.1001/jama.2020.2648CrossRefPubMed

35.

Chen L, Li Q, Zheng D et al (2020) Clinical characteristics of pregnant women with COVID-19 in Wuhan. China N Engl J Med 382:e100. https://doi.org/10.1056/NEJMc2009226CrossRefPubMed

36.

Liu Y, Chen H, Tang K et al (2020) Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect. https://doi.org/10.1016/j.jinf.2020.02.028CrossRefPubMedPubMedCentral

37.

Luo Y, Yin K (2020) Management of pregnant women infected with COVID-19. Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30191-2CrossRefPubMedPubMedCentral

38.

ICNARC report on COVID-19 in critical care. In: ICNARC, ed., 2020. https://www.icnarc.org/Our-Audit/Audits/Cmp/Reports. Accessed 17Apr 2020

39.

Liu D, Li L, Wu X et al (2020) Pregnancy and perinatal outcomes of women with coronavirus disease (COVID-19) Pneumonia: a preliminary analysis. Am J Roentgenol. https://doi.org/10.2214/AJR.20.23072CrossRef

40.

Wong SF, Chow KM, Leung TN et al (2004) Pregnancy and perinatal outcomes with the severe acute respiratory syndrome. Am J Obstet Gynecol 191:292–297. https://doi.org/10.1016/j.ajog.2003.11.019CrossRefPubMedPubMedCentral

41.

Alfaraj SH, Al-Tawfiq JA, Memish ZA (2019) Middle east respiratory syndrome coronavirus (MERS-CoV) infection during pregnancy: report of two cases & review of the literature. J Microbiol Immunol Infect. 52:501–503. https://doi.org/10.1016/j.jmii.2018.04.005CrossRefPubMed

42.

Chen S, Huang B, Luo DJ et al (2020) Pregnant woman with new coronavirus infection: clinical characteristics and placental pathological analysis of three cases. Zhonghua Bing Li Xue Za Zhi 49:E005. https://doi.org/10.3760/cma.j.cn112151-20200225-00138CrossRef

43.

Mullins E, Evans D, Viner R et al (2020) Coronavirus in pregnancy and delivery: a rapid review. Ultrasound in Obstet Gynaecol 55:586–592. https://doi.org/10.1002/uog.22014CrossRef

44.

Royal College of Obstetricians and Gynaecologists. Reducing the Risk of Venous Thromboembolism during Pregnancy and the Puerperium. Green-top Guideline No. 37a. Accessed 2015

45.

Practical guidance for the prevention of thrombosis and management of coagulopathy and disseminated intravascular coagulation of patients infected with COVID-19 (2020) https://thrombosisuk.org/covid-19-thrombosis.php Accessed 07 Apr 2020

46.

Reverter JC, Tàssies D, Font J, Monteagudo J, Escolar G, Ingelmo M, Ordinas A (1996) Hypercoagulable state in patients with the antiphospholipid syndrome is related to high induced tissue factor expression on monocytes and too low free protein s. Arterioscler Thromb Vasc Biol 16(11):1319–1326. https://doi.org/10.1161/01.ATV.16.11.1319CrossRefPubMed

47.

Listing J, Gerhold K, Zink A (2012) The risk of infections associated with rheumatoid arthritis, with its comorbidity and treatment. Rheumatology (Oxford) 52:53–61. https://doi.org/10.1093/rheumatology/kes305CrossRef

48.

Tudesq J-J, Cartron G, Rivière S, Morquin D, Iordache L, Mahr A (2018) Clinical and microbiological characteristics of the infections in patients treated with rituximab for autoimmune and/or malignant hematological disorders. Autoimmun Rev 17:115–124. https://doi.org/10.1016/j.autrev.2017.11.015CrossRefPubMed

49.

EULAR guidance for patients during the Covid-19 outbreak. https://www.eular.org/eular_guidance_for_patients_covid19_outbreak.cfm Accessed 19 Mar 2020

50.

ACR guidance for patients during the Covid-19 outbreak. https://www.rheumatology.org/announcements. Accessed 29 Mar 2020

51.

BSR guidance for patients during the Covid-19 outbreak. https://www.rheumatology.org.uk/News-Policy/Details/Covid19 Coronavirus-update-members Accessed 29 Mar 2020

52.

Australian Rheumatology Association guidance for patients during the Covid-19 outbreak. https://arthritisaustralia.com.au/advice-regarding-coronavirus-covid-19-from-the-australian-rheumatology-association/ Accessed 19 Mar 2020

53.

World Health Organization. (2004). AIDE-MEMOIRE. For infection prevention and control in a health care facility. https://apps.who.int/iris/handle/10665/130165 Accessed 2004.

54.

World Health Organization. (2020). Clinical Management of Severe Acute Respiratory Infection When Novel Coronavirus (2019-nCoV) Infection is Suspected: Interim Guidance. Accessed 28 Jan 2020

55.

Bin Chao. (2020) Chinese guidelines of diagnosis and treatment of COVID-19 (7th version). https://www.sforl.org/wp-content/uploads/2020/03/WUHAN-Experience.pdf Accessed 18 Mar 2020

56.

Favalli E, Biggioggero M, Maioli G et al (2020) Baricitinib for COVID-19: a suitable treatment? Lancet Infect Dis. https://doi.org/10.1016/S1473-3099(20)30262-0CrossRefPubMedPubMedCentral

57.

Cantini F, Niccoli L, Matarrese D et al (2020) Baricitinib therapy in COVID-19: A pilot study on the safety and clinical impact. J Infect. https://doi.org/10.1016/j.jinf.2020.04.017CrossRefPubMedPubMedCentral

58.

Stebbing J, Phelan A, Griffin I et al (2020) COVID-19: combining antiviral and anti-inflammatory treatments. Lancet Infect Dis 20:400–402. https://doi.org/10.1016/S1473-3099(20)30132-8CrossRefPubMedPubMedCentral

59.

Tisoncik JR, Korth MJ, Simmons CP, Farrar J, Martin TR, Katze MG (2012) Into the eye of the cytokine storm. Microbiol Mol Biology Rev Mmbr 76:16–32. https://doi.org/10.1128/MMBR.05015-11CrossRef

60.

Shakoory B, Carcillo JA, Chatham WW, Amdur RL, Zhao H, Dinarello CA (2016) Interleukin-1 receptor blockade is associated with reduced mortality in sepsis patients with features of macrophage activation syndrome. Crit Care Med 44:275–281. https://doi.org/10.1097/CCM.0000000000001402CrossRefPubMedPubMedCentral

61.

Papagoras C, Voulgari PV, Drosos AA (2013) Atherosclerosis and cardiovascular disease in the spondyloarthritides, particularly ankylosing spondylitis and psoriatic arthritis. Clin Exp Rheumatol 31(4):612–620PubMed

62.

Papagoras C, Markatseli TE, Saougou I et al (2014) Cardiovascular risk profile in patients with spondyloarthritis. Joint Bone Spine 81(1):57–63. https://doi.org/10.1016/j.jbspin.2013.03.019CrossRefPubMed

63.

National Psoriasis Foundation Medical Board COVID-19 Recommendations for patients with psoriatic disease. https://www.psoriasis.org/advance/coronavirus Accessed 10 Apr 2020

64.

Popescu C, Pintilie AM, Bojinca V, Balanescu A, Ionescu R (2014) Cardiovascular risk in psoriatic arthritis – a cross-sectional study. Maedica (Buchar) 9(1):19–24

65.

Mathian A, Mahevas M, Rohmer J et al (2020) Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine. Ann Rheum Dis. https://doi.org/10.1136/annrheumdis-2020-217566CrossRefPubMed

66.

Zhou F, Yu T, Du R et al (2020) Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study. Lancet 395:1054–62. https://doi.org/10.1016/S0140-6736(20)30566-3CrossRefPubMedPubMedCentral

67.

ICNARC. Report on 2249 patients critically ill with COVID-19. https://www.icnarc.org/DataServices/Attachments/Download/76a7364b-4b76-ea11-9124-00505601089b Accessed 04 Apr 2020

68.

Askanase AD, Khalili L, Buyon JP (2020) Thoughts on COVID-19 and autoimmune diseases. Lupus Sci Med. https://doi.org/10.1136/lupus-2020-000396CrossRefPubMedPubMedCentral

Titel: Coronavirus disease 2019 (COVID-19) during pregnancy in patients with rheumatic diseases
Publikationsdatum: 15.09.2020
Schlagwort: COVID-19
Erschienen in: Rheumatology International / Ausgabe 11/2020
Print ISSN: 0172-8172
Elektronische ISSN: 1437-160X
DOI: https://doi.org/10.1007/s00296-020-04698-y

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