Erschienen in:
05.09.2020 | COVID-19 | Research Letter
Zur Zeit gratis
Markers of coagulation dysfunction and inflammation in diabetic and non-diabetic COVID-19
verfasst von:
Seshadri Reddy Varikasuvu, Saurabh Varshney, Naveen Dutt
Erschienen in:
Journal of Thrombosis and Thrombolysis
|
Ausgabe 4/2021
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Abstract
Coagulation dysfunction and inflammatory status were compared between diabetic and non-diabetic COVID-19 patients. The standardized mean difference (SMD) and its 95% confidence interval (CI) was computed for the difference of inflammatory and hypercoagulability markers. The levels of serum ferritin (standardized mean difference-SMD: 0.47, CI 0.17–0.77, p = 0.002), C-reactive protein (SMD = 0.53, CI 0.20–0.86, p = 0.002), interleukin-6 (SMD = 0.31, CI 0.09–0.52, p = 0.005), fibrinogen (SMD = 0.31, CI 0.09–0.54, p = 0.007) and D-dimers (SMD = 0.54, CI 0.16–0.91, p = 0.005) were significantly higher in diabetic COVID-19 cases as compared to non-diabetic COVID-19 patients, suggesting more susceptibility of diabetic COVID-19 patients to coagulation dysfunction and inflammatory storm.