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Erschienen in:
17.05.2016
Cryoballoon ablation for pulmonary vein isolation in patients with atrial fibrillation: preliminary results using novel short-tip cryoballoon
Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 1/2016
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Purpose
In this study, we aimed to report our preliminary experience regarding the impact of the novel short-tip (ST) cryoballoon (CB) on procedural efficacy and signal quality during pulmonary vein (PV) isolation for both paroxysmal and persistent atrial fibrillation.
Methods
Between March, 2015, and August, 2015, we enrolled a total of 64 patients (47 patients male, 73 %) with a mean age of 60 ± 11 years. In the study population, 31 patients (48 %) underwent PVI using Advance (ADV) CB and 33 (52 %) patients with ST CB. In all patients, a 28-mm balloon was used.
Results
Acute procedural success rates were 100 % for the entire study population. A statistically insignificant increase in the percentage of PV signal recordings was observed with ST CB in all PVs compared to ADV CB [88 vs. 81 % for left superior PV (LSPV), 82 vs. 78 % for left inferior PV (LIPV), 85 vs. 84 % for right superior PV (RSPV), 82 vs. 71 % for right inferior PV (RIPV), p < 0.05]. Additionally, the difference in minimum temperature reached during the procedure per PV was not statistically significant between ST CB and ADV CB except the LIPV (LSPV −44.2 ± 5.9 vs. −45.6 ± 5.3 °C, p = 0.970; LIPV −38.7 ± 4.6 °C vs −44.6 ± 6.8 °C, p < 0.001; RSPV −45.6 ± 7.4 °C vs.−47.2 ± 6.1 °C, p = 0.168; RIPV −41.4 ± 5.1 °C vs.−43.7 ± 6.3 °C, p = 0.360). Time to isolation for each PV was similar between ST and ADV CB (p > 0.05).
Conclusion
Our preliminary findings indicated similar acute procedural success for the novel ST CB compared with second generation ADV CB. The increase in the ratio of PV signal recordings obtained during the PVI using the novel ST CB was not significant.