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Erschienen in: Irish Journal of Medical Science (1971 -) 2/2019

24.08.2018 | Original Article

CT cervico-cerebral angiography in acute stroke. Can we justify aortic arch imaging?

verfasst von: Gavin Sugrue, Michael K. O’Reilly, Danielle Byrne, Matthew T. Crockett, Sean Murphy, Eoin C. Kavanagh

Erschienen in: Irish Journal of Medical Science (1971 -) | Ausgabe 2/2019

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Abstract

Objectives

Computed tomography cervico-cerebral angiography (CTCCA) plays a pivotal role in the evaluation of acute stroke. Currently no evidence justifies the inclusion of the upper chest in the CTCCA field of view. The aim of this study was to assess the prevalence and clinical significance of vascular findings identified on CTCCA in the head, neck, and upper chest regions in patients presenting with acute stroke symptoms.

Methods

A retrospective review of radiology images and reports of 900 consecutive patients (425 men, 475 women; mean age 63.2 years, age range 19–99 years) with a suspected acute stroke who underwent CTCCA in the emergency department between January 2011 and July 2016. Clinically significant vascular CTCCA findings were recorded for each patient within the head, neck, and upper chest regions, respectively.

Results

Of the 900 patients, clinically significant vascular CTCCA findings were identified in 404/900 (44.8%) patients. 218/900 (24.2%) were located within the head region; 174/900 (19.3%) within the neck; and 12/900 (2.4%) in the upper chest. Of the 12 vascular findings located within the upper chest, 3/900 (0.33%) were related to a clinically significant posterior circulation infarct.

Conclusions

Routine inclusion of the upper chest on CTCCA is currently difficult to justify in the evaluation of a suspected acute anterior circulation stroke, contributing significantly to total radiation dose without demonstrating significant extra-cranial vascular findings. Prospective studies adopting narrower fields of view excluding the upper chest are necessary.
Literatur
1.
Zurück zum Zitat Powers WJ, Derdeyn CP, Biller J et al (2015) American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment. Stroke 46(10):3020–3035CrossRefPubMed Powers WJ, Derdeyn CP, Biller J et al (2015) American Heart Association/American Stroke Association focused update of the 2013 guidelines for the early management of patients with acute ischemic stroke regarding endovascular treatment. Stroke 46(10):3020–3035CrossRefPubMed
2.
Zurück zum Zitat Esteban JM, Cervera V (2004) Perfusion CT and angio CT in the assessment of acute stroke. Neuroradiology 46(9):705–715CrossRefPubMed Esteban JM, Cervera V (2004) Perfusion CT and angio CT in the assessment of acute stroke. Neuroradiology 46(9):705–715CrossRefPubMed
3.
Zurück zum Zitat Jauch EC, Saver JL, Adams HP et al (2013) Guidelines for the early management of patients with acute ischemic stroke. Stroke 44(3):870–947CrossRefPubMed Jauch EC, Saver JL, Adams HP et al (2013) Guidelines for the early management of patients with acute ischemic stroke. Stroke 44(3):870–947CrossRefPubMed
4.
Zurück zum Zitat Jovin TG, Chamorro A, Cobo E et al (2015) Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 372(24):2296–2306CrossRefPubMed Jovin TG, Chamorro A, Cobo E et al (2015) Thrombectomy within 8 hours after symptom onset in ischemic stroke. N Engl J Med 372(24):2296–2306CrossRefPubMed
5.
Zurück zum Zitat Saver JL, Goyal M, Bonafe A et al (2015) Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 372(24):2285–2295CrossRefPubMed Saver JL, Goyal M, Bonafe A et al (2015) Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. N Engl J Med 372(24):2285–2295CrossRefPubMed
6.
Zurück zum Zitat Campbell BC, Mitchell PJ, Kleinig TJ et al (2015) Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 372(11):1009–1018CrossRefPubMed Campbell BC, Mitchell PJ, Kleinig TJ et al (2015) Endovascular therapy for ischemic stroke with perfusion-imaging selection. N Engl J Med 372(11):1009–1018CrossRefPubMed
7.
Zurück zum Zitat Goyal M, Demchuk AM, Menon BK et al (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372(11):1019–1030CrossRefPubMed Goyal M, Demchuk AM, Menon BK et al (2015) Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med 372(11):1019–1030CrossRefPubMed
8.
Zurück zum Zitat Berkhemer OA, Fransen PS, Beumer D et al (2015) A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015(372):11–20CrossRef Berkhemer OA, Fransen PS, Beumer D et al (2015) A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med 2015(372):11–20CrossRef
9.
Zurück zum Zitat Smith-Bindman R, Lipson J, Marcus R et al (2009) Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 169(22):2078–2086CrossRefPubMedPubMedCentral Smith-Bindman R, Lipson J, Marcus R et al (2009) Radiation dose associated with common computed tomography examinations and the associated lifetime attributable risk of cancer. Arch Intern Med 169(22):2078–2086CrossRefPubMedPubMedCentral
10.
Zurück zum Zitat Mettler FA Jr, Wiest PW, Locken JA, Kelsey CA (2000) CT scanning: patterns of use and dose. J Radiol Prot 20(4):353–359CrossRefPubMed Mettler FA Jr, Wiest PW, Locken JA, Kelsey CA (2000) CT scanning: patterns of use and dose. J Radiol Prot 20(4):353–359CrossRefPubMed
11.
Zurück zum Zitat Almandoz JE, Romero JM, Pomerantz SR et al (2010) Computed tomography angiography of the carotid and cerebral circulation. Radiol Clin N Am 48(2):265–281CrossRef Almandoz JE, Romero JM, Pomerantz SR et al (2010) Computed tomography angiography of the carotid and cerebral circulation. Radiol Clin N Am 48(2):265–281CrossRef
12.
Zurück zum Zitat Goyal M, Menon BK, Hill MD et al (2014) Consistently Achieving computed tomography to endovascular recanalization <90 Minutes. Stroke 45(12):e252–e256CrossRefPubMed Goyal M, Menon BK, Hill MD et al (2014) Consistently Achieving computed tomography to endovascular recanalization <90 Minutes. Stroke 45(12):e252–e256CrossRefPubMed
13.
Zurück zum Zitat Menon BK, Campbell BC, Levi C et al (2015) Role of imaging in current acute ischemic stroke workflow for endovascular therapy. Stroke STROKEAHA-115 Menon BK, Campbell BC, Levi C et al (2015) Role of imaging in current acute ischemic stroke workflow for endovascular therapy. Stroke STROKEAHA-115
14.
Zurück zum Zitat Menon BK, d’Esterre CD, Qazi EM et al (2015) Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke. Radiology 275(2):510–520CrossRefPubMed Menon BK, d’Esterre CD, Qazi EM et al (2015) Multiphase CT angiography: a new tool for the imaging triage of patients with acute ischemic stroke. Radiology 275(2):510–520CrossRefPubMed
15.
Zurück zum Zitat Yamauchi-Kawara C, Fujii K, Aoyama T, Yamauchi M, Koyama S (2010) Radiation dose evaluation in multidetector-row CT imaging for acute stroke with an anthropomorphic phantom. Br J Radiol 83(996):1029–1041CrossRefPubMedPubMedCentral Yamauchi-Kawara C, Fujii K, Aoyama T, Yamauchi M, Koyama S (2010) Radiation dose evaluation in multidetector-row CT imaging for acute stroke with an anthropomorphic phantom. Br J Radiol 83(996):1029–1041CrossRefPubMedPubMedCentral
16.
Zurück zum Zitat Deipolyi AR, Hamberg LM, Gonzaléz RG et al (2015) Diagnostic yield of emergency department arch-to-vertex CT angiography in patients with suspected acute stroke. Am J Neuroradiol 36(2):265–268CrossRefPubMedPubMedCentral Deipolyi AR, Hamberg LM, Gonzaléz RG et al (2015) Diagnostic yield of emergency department arch-to-vertex CT angiography in patients with suspected acute stroke. Am J Neuroradiol 36(2):265–268CrossRefPubMedPubMedCentral
18.
Zurück zum Zitat Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, Levine SR, Chaturvedi S, Kasner SE, Benesch CG, Sila CA, Jovin TG, Romano JG, Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators (2005) Warfarin-aspirin symptomatic intracranial disease trial investigators. Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 352:1305–1316. https://doi.org/10.1056/NEJMoa043033 CrossRefPubMed Chimowitz MI, Lynn MJ, Howlett-Smith H, Stern BJ, Hertzberg VS, Frankel MR, Levine SR, Chaturvedi S, Kasner SE, Benesch CG, Sila CA, Jovin TG, Romano JG, Warfarin-Aspirin Symptomatic Intracranial Disease Trial Investigators (2005) Warfarin-aspirin symptomatic intracranial disease trial investigators. Comparison of warfarin and aspirin for symptomatic intracranial arterial stenosis. N Engl J Med 352:1305–1316. https://​doi.​org/​10.​1056/​NEJMoa043033 CrossRefPubMed
19.
20.
21.
22.
23.
Zurück zum Zitat Knauth M, von Kummer R, Jansen O et al (1997) Potential of CT angiography in acute ischemic stroke. Am J Neuroradiol 18(6):1001–1010PubMedPubMedCentral Knauth M, von Kummer R, Jansen O et al (1997) Potential of CT angiography in acute ischemic stroke. Am J Neuroradiol 18(6):1001–1010PubMedPubMedCentral
24.
Zurück zum Zitat Amy YX, Zerna C, Assis Z, Holodinsky JK et al (2016) Multiphase CT angiography increases detection of anterior circulation intracranial occlusion. Neurology 87(6):609–616 Amy YX, Zerna C, Assis Z, Holodinsky JK et al (2016) Multiphase CT angiography increases detection of anterior circulation intracranial occlusion. Neurology 87(6):609–616
25.
Zurück zum Zitat Volny O, Cimflova P, Kadlecova P et al (2017) Single-phase versus multiphase CT angiography in middle cerebral artery clot detection—benefits for less experienced radiologists and neurologists. J Stroke Cerebrovasc Dis 26(1):19–24CrossRefPubMed Volny O, Cimflova P, Kadlecova P et al (2017) Single-phase versus multiphase CT angiography in middle cerebral artery clot detection—benefits for less experienced radiologists and neurologists. J Stroke Cerebrovasc Dis 26(1):19–24CrossRefPubMed
26.
Zurück zum Zitat Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA (2018) Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 378(1):11–21CrossRefPubMed Nogueira RG, Jadhav AP, Haussen DC, Bonafe A, Budzik RF, Bhuva P, Yavagal DR, Ribo M, Cognard C, Hanel RA, Sila CA (2018) Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N Engl J Med 378(1):11–21CrossRefPubMed
27.
Zurück zum Zitat Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A (2018 Feb 22) Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med 378(8):708–718CrossRefPubMedPubMedCentral Albers GW, Marks MP, Kemp S, Christensen S, Tsai JP, Ortega-Gutierrez S, McTaggart RA, Torbey MT, Kim-Tenser M, Leslie-Mazwi T, Sarraj A (2018 Feb 22) Thrombectomy for stroke at 6 to 16 hours with selection by perfusion imaging. N Engl J Med 378(8):708–718CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Shin JH, Suh DC, Choi CG, Lee HK (2000) Vertebral artery dissection: spectrum of imaging findings with emphasis on angiography and correlation with clinical presentation. RadioGraphics 20:1687–1696CrossRefPubMed Shin JH, Suh DC, Choi CG, Lee HK (2000) Vertebral artery dissection: spectrum of imaging findings with emphasis on angiography and correlation with clinical presentation. RadioGraphics 20:1687–1696CrossRefPubMed
29.
Zurück zum Zitat Macdonald S, Lee R, Williams R et al (2009) Towards safer carotid artery stenting. Stroke 40(5):1698–1703CrossRefPubMed Macdonald S, Lee R, Williams R et al (2009) Towards safer carotid artery stenting. Stroke 40(5):1698–1703CrossRefPubMed
30.
Zurück zum Zitat Faggioli G, Ferri M, Rapezzi C et al (2009) Atherosclerotic aortic lesions increase the risk of cerebral embolism during carotid stenting in patients with complex aortic arch anatomy. J Vasc Surg 49(1):80–85CrossRefPubMed Faggioli G, Ferri M, Rapezzi C et al (2009) Atherosclerotic aortic lesions increase the risk of cerebral embolism during carotid stenting in patients with complex aortic arch anatomy. J Vasc Surg 49(1):80–85CrossRefPubMed
31.
Zurück zum Zitat Faggioli G, Ferri M, Gargiulo M et al (2007) Measurement and impact of proximal and distal tortuosity in carotid stenting procedures. J Vasc Surg 46(6):1119–1124CrossRefPubMed Faggioli G, Ferri M, Gargiulo M et al (2007) Measurement and impact of proximal and distal tortuosity in carotid stenting procedures. J Vasc Surg 46(6):1119–1124CrossRefPubMed
32.
Zurück zum Zitat Faggioli GL, Ferri M, Freyrie A et al (2007) Aortic arch anomalies are associated with increased risk of neurological events in carotid stent procedures. Eur J Vasc Endovasc Surg 33(4):436–441CrossRefPubMed Faggioli GL, Ferri M, Freyrie A et al (2007) Aortic arch anomalies are associated with increased risk of neurological events in carotid stent procedures. Eur J Vasc Endovasc Surg 33(4):436–441CrossRefPubMed
33.
Zurück zum Zitat Heldner MR, Hsieh K, Broeg-Morvay A et al (2016) Clinical prediction of large vessel occlusion in anterior circulation stroke: mission impossible? J Neurol 263(8):1633–1640CrossRefPubMed Heldner MR, Hsieh K, Broeg-Morvay A et al (2016) Clinical prediction of large vessel occlusion in anterior circulation stroke: mission impossible? J Neurol 263(8):1633–1640CrossRefPubMed
34.
Zurück zum Zitat Cooray C, Fekete K, Mikulik R et al (2015) Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke 10(6):822–829CrossRefPubMed Cooray C, Fekete K, Mikulik R et al (2015) Threshold for NIH stroke scale in predicting vessel occlusion and functional outcome after stroke thrombolysis. Int J Stroke 10(6):822–829CrossRefPubMed
35.
Zurück zum Zitat Vanacker P, Heldner MR, Amiguet M, Faouzi M, Cras P, Ntaios G, Arnold M, Mattle HP, Gralla J, Fischer U, Michel P (2016) Prediction of large vessel occlusions in acute stroke: National Institute of Health Stroke Scale is hard to beat. Crit Care Med 44(6):e336–e343CrossRefPubMed Vanacker P, Heldner MR, Amiguet M, Faouzi M, Cras P, Ntaios G, Arnold M, Mattle HP, Gralla J, Fischer U, Michel P (2016) Prediction of large vessel occlusions in acute stroke: National Institute of Health Stroke Scale is hard to beat. Crit Care Med 44(6):e336–e343CrossRefPubMed
36.
Zurück zum Zitat de la Ossa NP, Carrera D, Gorchs M et al (2014) Design and validation of a prehospital stroke scale to predict large arterial occlusion. Stroke 45(1):87–91CrossRef de la Ossa NP, Carrera D, Gorchs M et al (2014) Design and validation of a prehospital stroke scale to predict large arterial occlusion. Stroke 45(1):87–91CrossRef
37.
Zurück zum Zitat Boussel L, Cakmak S, Wintermark M, Nighoghossian N, Loffroy R, Coulon P, Derex L, Cho TH, Douek PC (2011) Ischemic stroke: etiologic work-up with multidetector CT of heart and extra-and intracranial arteries. Radiology 258(1):206–212CrossRefPubMed Boussel L, Cakmak S, Wintermark M, Nighoghossian N, Loffroy R, Coulon P, Derex L, Cho TH, Douek PC (2011) Ischemic stroke: etiologic work-up with multidetector CT of heart and extra-and intracranial arteries. Radiology 258(1):206–212CrossRefPubMed
38.
Zurück zum Zitat Hayashi N, Ohtani Y, Ohtani O et al (2005) Surgical anatomy of the cervical carotid artery for carotid endarterectomy. Neurol Med Chir 45(1):25–30CrossRef Hayashi N, Ohtani Y, Ohtani O et al (2005) Surgical anatomy of the cervical carotid artery for carotid endarterectomy. Neurol Med Chir 45(1):25–30CrossRef
39.
Zurück zum Zitat Michalinos A, Chatzimarkos M, Arkadopoulos N et al (2016) Anatomical considerations on surgical anatomy of the carotid bifurcation. Anat Res Int 7:2016 Michalinos A, Chatzimarkos M, Arkadopoulos N et al (2016) Anatomical considerations on surgical anatomy of the carotid bifurcation. Anat Res Int 7:2016
40.
Zurück zum Zitat McNamara JR, Fulton GJ, Manning BJ (2015) Three-dimensional computed tomographic reconstruction of the carotid artery: identifying high bifurcation. Eur J Vasc Endovasc Surg 49(2):147–153CrossRefPubMed McNamara JR, Fulton GJ, Manning BJ (2015) Three-dimensional computed tomographic reconstruction of the carotid artery: identifying high bifurcation. Eur J Vasc Endovasc Surg 49(2):147–153CrossRefPubMed
Metadaten
Titel
CT cervico-cerebral angiography in acute stroke. Can we justify aortic arch imaging?
verfasst von
Gavin Sugrue
Michael K. O’Reilly
Danielle Byrne
Matthew T. Crockett
Sean Murphy
Eoin C. Kavanagh
Publikationsdatum
24.08.2018
Verlag
Springer London
Erschienen in
Irish Journal of Medical Science (1971 -) / Ausgabe 2/2019
Print ISSN: 0021-1265
Elektronische ISSN: 1863-4362
DOI
https://doi.org/10.1007/s11845-018-1888-9

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